Official Title: Possible Pharmacological Effect of Quercetin in the Management of Hyperuricemia
Status: COMPLETED
Status Verified Date: 2024-10
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: No
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: Quercetin a natural flavonoid found in various fruits and vegetables has gained attention for its potential role in managing hyperuricemia Emerging evidence suggests that quercetin may reduce plasma uric acid levels by inhibiting xanthine oxidase an enzyme responsible for uric acid production Additionally its anti-inflammatory and antioxidant properties could help mitigate the oxidative stress and inflammation associated with hyperuricemia As a result quercetin supplementation offers a promising avenue for therapeutic intervention in conditions like gout and other uric acid-related disorders
Detailed Description: In the present retrospective cross-sectional observational study the investigators assessed the potential pharmacological effect of supplemental quercetin on the plasma uric acid levels of health adults These participants visited nutritional clinics in Italy during the Coronavirus disease COVID-19 pandemic for general health check-up in real-life to enhance their immune system with supplements aimed at providing additional protection against COVID-19 infection The supplements either quercetin or probiotic Streptococcus salivarius K12 BLIS K12 were advised randomly to the participants for 90 days tailored to individual needs and in the absence of any pre-defined criteria