Ignite Creation Date:
2024-05-05 @ 11:22 AM
Last Modification Date:
2024-10-26 @ 9:04 AM
Study NCT ID:
NCT00004364
Status:
UNKNOWN
Last Update Posted:
2006-02-22
First Post:
1999-10-18
Brief Title:
Study of Novel Types of Familial Diabetes Insipidus
Sponsor:
National Center for Research Resources NCRR
Organization:
Office of Rare Diseases ORD
Study Overview
Official Title:
None
Status:
UNKNOWN
Status Verified Date:
2006-02
Last Known Status:
ACTIVE_NOT_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
OBJECTIVES
I Define the phenotype and genotype of previously unrecognized types of familial diabetes insipidus FDI in kindreds with atypical or novel forms of FDI
I Define the phenotype and genotype of previously unrecognized types of familial diabetes insipidus FDI in kindreds with atypical or novel forms of FDI
Detailed Description:
PROTOCOL OUTLINE Participants undergo a series of tests to determine the presence absence cause natural history clinical status and mode of inheritance of their type of diabetes insipidus DI The studies include measurements of basal fluid intake and urine output plasma vasopressin during standard fluid deprivation or waterloadsaline infusion tests and changes in water balance during a therapeutic trial of DDAVP If clinically indicated echocardiograms and assays of plasma catecholes and renin are also completed
Linkage analysis is performed for all participants kindreds with the Marfan-like syndrome are also studied for the fibrillin-1 genotype
Participants determined to have DI are treated with desmopressin for 2 days
Linkage analysis is performed for all participants kindreds with the Marfan-like syndrome are also studied for the fibrillin-1 genotype
Participants determined to have DI are treated with desmopressin for 2 days
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| NU-570 | None | None | None |