Ignite Creation Date:
2024-05-05 @ 11:22 AM
Last Modification Date:
2024-10-26 @ 9:02 AM
Study NCT ID:
NCT00001275
Status:
COMPLETED
Last Update Posted:
2017-10-06
First Post:
1999-11-03
Brief Title:
Ovarian Follicle Function in Patients With Primary Ovarian Failure
Sponsor:
Eunice Kennedy Shriver National Institute of Child Health and Human Development NICHD
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
Ovarian Follicle Function in Patients With Primary Ovarian Insufficiency
Status:
COMPLETED
Status Verified Date:
2017-02-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
No proven therapy to restore ovarian function and fertility is available to patients with karyotypically normal spontaneous premature ovarian failure We know that one-half of these patients have primordial follicles remaining in the ovary and these follicles can function intermittently This is a diagnostic omnibus protocol that permits baseline clinical evaluation of patients with prematurem ovarian failure The findings will determine patients suitability for specifically focused therapeutic research protocols
Detailed Description:
No proven therapy to restore ovarian function and fertility is available to patients with karyotypically normal spontaneous primary ovarian insufficiency We know that more than one-half of these patients have primordial follicles remaining in the ovary and these follicles can function intermittently This protocol permitted baseline clinical evaluation of patients with primary ovarian insufficiency and ongoing observation of the natural history of the disorder The protocol is now in the follow up and analysis phase and is not now recruiting new patients Now a major aim of the protocol is to investigate large scale medical sequencing as a method by which to uncover mechanisms of primary ovarian insufficiency and to assist in the management of women with this condition This will involve a community-based participatory research approach
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 91-CH-0127 | None | None | None |