Ignite Creation Date:
2024-05-05 @ 11:22 AM
Last Modification Date:
2024-10-26 @ 9:03 AM
Study NCT ID:
NCT00002479
Status:
COMPLETED
Last Update Posted:
2012-05-30
First Post:
1999-11-01
Brief Title:
Tretinoin in Treating Patients With Mycosis Fungoides or Sezary Syndrome
Sponsor:
Northwestern University
Organization:
Northwestern University
Study Overview
Official Title:
Phase II Trial of Tretinoin TRA in Patients With Mycosis FungoidesSezary Syndrome
Status:
COMPLETED
Status Verified Date:
2012-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
RATIONALE Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die
PURPOSE Phase II trial to study the effectiveness of tretinoin in treating patients who have any stage mycosis fungoides or Sezary syndrome
PURPOSE Phase II trial to study the effectiveness of tretinoin in treating patients who have any stage mycosis fungoides or Sezary syndrome
Detailed Description:
OBJECTIVES I Determine the efficacy of tretinoin TRA in patients with mycosis fungoidesSezary syndrome II Evaluate the spectrum of toxicity of TRA in this patient population
OUTLINE Nonrandomized study Single-agent Chemotherapy Tretinoin All-trans-Retinoic Acid TRA NSC-122758
PROJECTED ACCRUAL If 1 or more of the first 15 evaluable patients experience an objective response then 20 additional patients will be entered It is anticipated that the accrual rate will be 1-2 patients per month
OUTLINE Nonrandomized study Single-agent Chemotherapy Tretinoin All-trans-Retinoic Acid TRA NSC-122758
PROJECTED ACCRUAL If 1 or more of the first 15 evaluable patients experience an objective response then 20 additional patients will be entered It is anticipated that the accrual rate will be 1-2 patients per month
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| NCI-T91-0136O | None | None | None |
| NU-T91-0136 | None | None | None |