Ignite Creation Date:
2024-05-05 @ 11:22 AM
Last Modification Date:
2024-10-26 @ 9:02 AM
Study NCT ID:
NCT00001886
Status:
COMPLETED
Last Update Posted:
2008-03-04
First Post:
1999-11-03
Brief Title:
Real Time 3-Dimensional Stress Echocardiography
Sponsor:
National Heart Lung and Blood Institute NHLBI
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
Real Time 3-Dimensional Stress Echocardiography
Status:
COMPLETED
Status Verified Date:
2000-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
An echocardiogram is an ultrasound technique used to gather information about the heart Standard echocardiograms create images of the heart in two dimensions thereby named 2D two-dimensional echocardiography A new technique has been developed allowing images to be taken of the heart in three dimensions real time 3D echocardiography
The 3D echocardiogram uses high frequency sound waves to see and record the movement and function of the heart muscle The echocardiogram is taken by placing an instrument called a transducer against the chest wall over the heart
In this study patients will undergo a dobutamine stress echocardiogram Dobutamine is drug that causes the heart to beat stronger and faster similar to how it acts when exercising Dobutamine allows researchers to tell if the heart is suffering from a lack of oxygen during exercise or other forms of stress or if it is permanently damaged
The purpose of this study is to determine whether stress 3D echocardiography is feasible and accurate in the detection of heart disease coronary artery disease Results of the 3D echocardiogram will be compared to results from standard 2D echocardiograms
The 3D echocardiogram uses high frequency sound waves to see and record the movement and function of the heart muscle The echocardiogram is taken by placing an instrument called a transducer against the chest wall over the heart
In this study patients will undergo a dobutamine stress echocardiogram Dobutamine is drug that causes the heart to beat stronger and faster similar to how it acts when exercising Dobutamine allows researchers to tell if the heart is suffering from a lack of oxygen during exercise or other forms of stress or if it is permanently damaged
The purpose of this study is to determine whether stress 3D echocardiography is feasible and accurate in the detection of heart disease coronary artery disease Results of the 3D echocardiogram will be compared to results from standard 2D echocardiograms
Detailed Description:
Stress echocardiography has become a valuable technique for the non-invasive detection of coronary artery disease Its accuracy has been shown to be superior to that of the exercise electrocardiogram and comparable to that of myocardial perfusion imaging The adequacy of stress echocardiography with conventional two-dimensional imaging however is highly dependent on operator expertise Further interpretation of test results is subjective and qualitative and is based on analysis of wall motion after arbitrary segmentation of the left ventricle Real time 3-dimensional RT3D echocardiography is a new technique that permits the unrestricted assessment of left ventricular wall motion and function in a single cardiac beat without ECG or respiratory gating We hypothesize that RT3D echocardiography will have similar or greater accuracy for the detection of wall motion abnormalities compared to the conventional two-dimensional examination We therefore propose to acquire RT3D echocardiographic images in patients with known or suspected coronary artery disease who undergo stress echocardiography We will correlate these results with findings from coronary angiography and compare the ability of RT3D echocardiography to detect coronary artery disease with that of the conventional two-dimensional exam
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 99-H-0074 | None | None | None |