Ignite Creation Date:
2025-12-24 @ 1:06 PM
Ignite Modification Date:
2026-01-25 @ 4:42 PM
Study NCT ID:
NCT02029261
Status:
WITHDRAWN
Last Update Posted:
2019-03-07
First Post:
2013-12-17
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Observational Study of Insulin Resistance and Muscle Wasting After Burn Injury
Sponsor:
Massachusetts General Hospital
Organization:
Study Overview
Official Title:
Project 4: Molecular Mechanisms in Burn-induced Insulin Resistance in Humans
Status:
WITHDRAWN
Status Verified Date:
2019-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Insufficient recruitment
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to examine important and significant problems, that of insulin resistance and muscle wasting after burn injury.
Detailed Description:
Burn injury induces insulin resistance and our investigators have previous shown the importance of insulin receptor substrate 1 (IRS-1)-mediated pathways. This project will establish the inhibitory effects of burn injury on IRS-1 mediated signaling in human skeletal muscle of burn patients.
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
Secondary ID Infos
| Secondary ID | Type | Domain | Link | View |
|---|---|---|---|---|
| 2P50GM021700-32A1 | NIH | None | https://reporter.nih.gov/quic… | View |