Ignite Creation Date:
2024-05-05 @ 11:22 AM
Last Modification Date:
2024-10-26 @ 9:01 AM
Study NCT ID:
NCT00000405
Status:
COMPLETED
Last Update Posted:
2016-06-09
First Post:
1999-11-03
Brief Title:
Effects of Jumping on Growing Bones
Sponsor:
Oregon State University
Organization:
Oregon State University
Study Overview
Official Title:
The Effects of Jumping on Growing Bones
Status:
COMPLETED
Status Verified Date:
2016-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
In this study we will investigate the effects of a high-impact exercise program involving jumping on bone mass the amount of bone of the hip and backbone in the growing skeleton We will also look at the effects of gradually stopping the jumping program on bone mass in the growing skeleton A high-impact exercise program may build more bone during childhood while the skeleton is still growing This may help prevent broken bones due to loss of bone mass later in life
We will recruit 200 children aged 5-10 to participate in the study For 6 months we will train the children in either a jumping or stretching program We will then gradually reduce the amount of exercise over 6 months We will measure bone mass in the hip and backbone at the start of the study after jumping and 6 months after the jumping program is stopped We will compare the results in the jumping and stretching groups
We will recruit 200 children aged 5-10 to participate in the study For 6 months we will train the children in either a jumping or stretching program We will then gradually reduce the amount of exercise over 6 months We will measure bone mass in the hip and backbone at the start of the study after jumping and 6 months after the jumping program is stopped We will compare the results in the jumping and stretching groups
Detailed Description:
Osteoporotic fractures are increasing at an alarming rate in this country and result in over 13 billion dollars in health costs annually Peak bone mass that is an individuals maximum bone mass at the completion of skeletal acquisition is an important determinant of fracture risk Thus maximizing peak bone mass may provide an effective strategy for preventing osteopenia and osteoporosis
Various investigators have postulated that increasing bone mass by 3-5 percent would reduce fracture risk by 20-30 percent Our data in collegiate female gymnasts demonstrate hip and spine bone mineral density values of up to 40 percent above values in normal age-matched controls and elite runners despite menstrual irregularities Further we have observed the dynamic response of bone to high-impact forces in gymnasts over the training season as bone increases of 2-5 percent
This is a randomized controlled exercise intervention designed to evaluate the effect of high-impact loading as a means to increase bone mass during development It will determine bone mass accrual and bone geometry at the lumbar spine and proximal femur in prepubescent girls and boys Further this study will evaluate the bone response from withdrawal of the stimulus over 6 months
We will recruit 200 pre-pubescent children during two separate years and randomly assign them to a jumping or a stretching group The jumping group will perform double leg jumps and the stretching group will act as a control Outcome variables include bone mineral density BMD at the spine and hip estimated bone volumetric density at the spine and cross-sectional geometry of the femoral neck and diaphysis
Implementing a specific bone-loading program during childhood will potentially allow the bone to increase both its mass and mineralization at an earlier age and therefore provide a larger foundation of mineralization for further growth throughout adolescence until skeletal maturity is reached We expect our findings to provide a basis for the design of strategies to build bone during growth and thereby reduce osteoporotic fractures
Various investigators have postulated that increasing bone mass by 3-5 percent would reduce fracture risk by 20-30 percent Our data in collegiate female gymnasts demonstrate hip and spine bone mineral density values of up to 40 percent above values in normal age-matched controls and elite runners despite menstrual irregularities Further we have observed the dynamic response of bone to high-impact forces in gymnasts over the training season as bone increases of 2-5 percent
This is a randomized controlled exercise intervention designed to evaluate the effect of high-impact loading as a means to increase bone mass during development It will determine bone mass accrual and bone geometry at the lumbar spine and proximal femur in prepubescent girls and boys Further this study will evaluate the bone response from withdrawal of the stimulus over 6 months
We will recruit 200 pre-pubescent children during two separate years and randomly assign them to a jumping or a stretching group The jumping group will perform double leg jumps and the stretching group will act as a control Outcome variables include bone mineral density BMD at the spine and hip estimated bone volumetric density at the spine and cross-sectional geometry of the femoral neck and diaphysis
Implementing a specific bone-loading program during childhood will potentially allow the bone to increase both its mass and mineralization at an earlier age and therefore provide a larger foundation of mineralization for further growth throughout adolescence until skeletal maturity is reached We expect our findings to provide a basis for the design of strategies to build bone during growth and thereby reduce osteoporotic fractures
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| NIAMS-009 | US NIH GrantContract | None | httpsreporternihgovquickSearchR01AR045655 |
| R01AR045655 | NIH | None | None |