Ignite Creation Date:
2024-05-05 @ 11:22 AM
Last Modification Date:
2024-10-26 @ 9:05 AM
Study NCT ID:
NCT00005914
Status:
COMPLETED
Last Update Posted:
2019-04-19
First Post:
2000-06-15
Brief Title:
Genetics of Recurrent Early-Onset Depression
Sponsor:
Stanford University
Organization:
Stanford University
Study Overview
Official Title:
Genetics of Recurrent Early-Onset Depression
Status:
COMPLETED
Status Verified Date:
2019-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
GenRED
Brief Summary:
This nationwide study will create a DNA collection to permit qualified scientists to search for depression-related genes
More than 750 families with at least two siblings who have experienced major depression are needed for the study Participants will be interviewed about psychiatric and family history and will be asked to provide a small blood specimen The identification of predisposing genes can lead to greater understanding of the brain mechanisms involved in severe depression which can in turn lead to the discovery of new treatments
A Certificate of Confidentiality from the federal government ensures that all information will be strictly confidential Blood specimens are identified only by code number not by name
Reimbursement is provided
More than 750 families with at least two siblings who have experienced major depression are needed for the study Participants will be interviewed about psychiatric and family history and will be asked to provide a small blood specimen The identification of predisposing genes can lead to greater understanding of the brain mechanisms involved in severe depression which can in turn lead to the discovery of new treatments
A Certificate of Confidentiality from the federal government ensures that all information will be strictly confidential Blood specimens are identified only by code number not by name
Reimbursement is provided
Detailed Description:
Studies of patterns of major depression in families suggest that 50 to 70 of the predisposition to major depression is caused by genes People with recurrent depression and earlier ages of onset have more relatives with depression There are probably at least several interacting genes rather than a single gene as in some disorders The identification of predisposing genes is likely to lead to greater understanding of the brain mechanisms involved in severe depression This could lead to the discovery of new treatments
This study will create a DNA collection to permit qualified scientists to search for depression-related genes More than 750 families with at least two siblings who have experienced major depression are needed for the study
Participants in this study will be interviewed about psychiatric and family history and will be asked for a small blood specimen Interviews can be conducted in person or by telephone For telephone interviews blood sample collection will be arranged at a location and time convenient for the participant Participants will also be asked for help in inviting other family members to participate No family member will be contacted without the permission and assistance of another participating family member
For information on a related study please follow this link
httpclinicaltrialsgovshowNCT00260182
This study will create a DNA collection to permit qualified scientists to search for depression-related genes More than 750 families with at least two siblings who have experienced major depression are needed for the study
Participants in this study will be interviewed about psychiatric and family history and will be asked for a small blood specimen Interviews can be conducted in person or by telephone For telephone interviews blood sample collection will be arranged at a location and time convenient for the participant Participants will also be asked for help in inviting other family members to participate No family member will be contacted without the permission and assistance of another participating family member
For information on a related study please follow this link
httpclinicaltrialsgovshowNCT00260182
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| DNBBS 7G-GRR | US NIH GrantContract | None | httpsreporternihgovquickSearchR01MH060866 |
| R01MH061686-01 | NIH | None | None |
| R01MH060912 | NIH | None | None |
| R01MH059552 | NIH | None | None |
| R01MH059541 | NIH | None | None |
| R01MH059542 | NIH | None | None |
| R01MH061686 | NIH | None | None |
| R01MH060866 | NIH | None | None |