Ignite Creation Date:
2025-12-24 @ 9:36 PM
Ignite Modification Date:
2026-01-04 @ 1:37 PM
Study NCT ID:
NCT07084532
Status:
COMPLETED
Last Update Posted:
2025-07-24
First Post:
2025-06-13
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Effects of Chewing Gum for Dry Mouth in Diabetes
Sponsor:
Çankırı Karatekin University
Organization:
Study Overview
Official Title:
The Effect of Chewing Gum on Dry Mouth in Individuals With Diabetes Mellitus
Status:
COMPLETED
Status Verified Date:
2025-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Dry mouth can seriously affect the quality of life of individuals because it affects chewing and swallowing functions. One of the diseases in which dry mouth occurs as a side effect of many diseases and/or treatments is diabetes mellitus. The aim of this study was to determine the effect of chewing gum on dry mouth in individuals with diabetes mellitus.
Detailed Description:
Diabetic autonomic neuropathy and microvascular changes in the oral mucosa are thought to cause decreased salivary secretion in individuals. Furthermore, poor blood glucose regulation and the accompanying polyuria can cause dehydration, leading to dry mouth and decreased salivary secretion. Decreased salivary secretion and subsequent changes in the oral mucosa have been reported in diabetic individuals with poor glycemic control.
Chewing gum is one of the activities that increases salivary secretion. It affects salivary pH and flow rate through both taste and mechanical stimulation, relieving dry mouth symptoms in individuals. While the unstimulated salivary flow rate in humans is 0.3 ml/min, this rate can reach 7 ml/min in someone chewing gum. Due to these known properties, chewing gum can be beneficial for dry mouth in individuals.
Literature reviews have shown that chewing gum reduces the feeling of dry mouth, increases salivary secretion, and quenches thirst. It is also believed that increased salivary secretion dilutes the bacterial load in the mouth, thus reducing the risk of periodontal disease. It is anticipated that chewing gum may be a factor that can improve the quality of life for patients with chronic diseases that require fluid restriction and a special diet. A review of the literature found no studies demonstrating the effect of gum chewing on dry mouth in individuals with diabetes.
Chewing gum is one of the activities that increases salivary secretion. It affects salivary pH and flow rate through both taste and mechanical stimulation, relieving dry mouth symptoms in individuals. While the unstimulated salivary flow rate in humans is 0.3 ml/min, this rate can reach 7 ml/min in someone chewing gum. Due to these known properties, chewing gum can be beneficial for dry mouth in individuals.
Literature reviews have shown that chewing gum reduces the feeling of dry mouth, increases salivary secretion, and quenches thirst. It is also believed that increased salivary secretion dilutes the bacterial load in the mouth, thus reducing the risk of periodontal disease. It is anticipated that chewing gum may be a factor that can improve the quality of life for patients with chronic diseases that require fluid restriction and a special diet. A review of the literature found no studies demonstrating the effect of gum chewing on dry mouth in individuals with diabetes.
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: