Ignite Creation Date:
2024-05-05 @ 11:23 AM
Last Modification Date:
2024-10-26 @ 9:06 AM
Study NCT ID:
NCT00018213
Status:
COMPLETED
Last Update Posted:
2009-01-21
First Post:
2001-07-03
Brief Title:
Naltrexone and Patch for Smokers
Sponsor:
US Department of Veterans Affairs
Organization:
VA Office of Research and Development
Study Overview
Official Title:
Naltrexone and Nicotine Replacement Effects on Cue Reactivity of Smokers
Status:
COMPLETED
Status Verified Date:
2007-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of this study is to investigate the effects of naltrexone alone and combined with nicotine patch on responses of smokers to smoking cues after 10 hours of tobacco deprivation Smokers who are not seeking treatment will be assigned to one of six conditions They will receive either 50 mg of naltrexone or a placebo pill and also will wear a nicotine patch that has 0 21 or 42 mg of nicotine during the tobacco deprivation period Both the day before the medication and deprivation and at the end of 10 hours of deprivation all will be exposed to lit cigarette cues in the laboratory Effects of the medications will be assessed on withdrawal measures urge to smoke psychophysiological measures and the topography of smoking three test cigarettes Studies such as these can help to identify potential interventions for tobacco cessation or withdrawal and thereby could result in less suffering and mortality
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None