Ignite Creation Date:
2024-05-05 @ 9:05 PM
Last Modification Date:
2024-10-26 @ 9:59 AM
Study NCT ID:
NCT00815685
Status:
COMPLETED
Last Update Posted:
2017-03-23
First Post:
2008-12-29
Brief Title:
A Pilot Study of Eicosapentaenoic Acid EPA in Patients With Cancer Cachexia
Sponsor:
H Lee Moffitt Cancer Center and Research Institute
Organization:
H Lee Moffitt Cancer Center and Research Institute
Study Overview
Official Title:
A Pilot Study of Eicosapentaenoic Acid EPA in Patients With Cancer Cachexia
Status:
COMPLETED
Status Verified Date:
2013-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The data collected through this pilot study will allow us to increase our understanding of cancer cachexia and the effect of Eicosapentaenoic Acid EPA on cancer cachexia Our long-term goal is to improve nutritional treatment and reduce illness in the cancer patient population
Detailed Description:
People who have cancer can get what is called cancer cachexia CC The symptoms of CC include getting full quickly when eating early satiety loss of appetite weakness resulting in weight loss and loss of lean body mass Even a weight loss of 5 in cancer patients reflects poor health hospitalization and a higher rate of illness Research shows that the elderly are at higher risk for deficiency of vitamins and trace minerals Other pre-existing chronic diseases and drug therapies in this population may increase the needs of certain nutrients Recent studies have also shown that advanced malnutrition is much more difficult to treat in the elderly than in younger adults and the consequences of failure to treat it delays recovery and can decrease function and quality of life At this time the ways to treat CC include giving medications to increase appetite and giving nutritional supplements that are high in calories and protein
Recent studies have shown that certain types of fats that are present in fish walnuts and other foods that we eat called Eicosapentaenoic acid EPA may help with weight gain especially gain in muscle and improve quality of life in patients with pancreatic cancer However EPA has never been studied in prevention of cancer cachexia in cancer patients showing early signs of weight loss Based on these early small studies it is clear that we need to study if and how EPA can prevent loss of muscle and weight in cancer patients and prevent this from becoming worse
Recent studies have shown that certain types of fats that are present in fish walnuts and other foods that we eat called Eicosapentaenoic acid EPA may help with weight gain especially gain in muscle and improve quality of life in patients with pancreatic cancer However EPA has never been studied in prevention of cancer cachexia in cancer patients showing early signs of weight loss Based on these early small studies it is clear that we need to study if and how EPA can prevent loss of muscle and weight in cancer patients and prevent this from becoming worse
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None