Ignite Creation Date:
2024-05-05 @ 9:14 PM
Last Modification Date:
2024-10-26 @ 10:01 AM
Study NCT ID:
NCT00849914
Status:
COMPLETED
Last Update Posted:
2012-10-16
First Post:
2009-02-20
Brief Title:
Expression Levels of microRNA Processing Enzymes Dicer and Drosha in Epithelial Skin Cancer
Sponsor:
Ruhr University of Bochum
Organization:
Ruhr University of Bochum
Study Overview
Official Title:
Expression Levels of microRNA Processing Enzymes Dicer and Drosha in Epithelial Skin Cancer
Status:
COMPLETED
Status Verified Date:
2012-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
MicroRNAs miRNAs are very small endogenous RNA molecules about 22-25 nucleotides in length capable of post-transcriptional gene regulation miRNAs bind to their target messenger RNAs mRNAs leading to cleavage or suppression of target mRNA translation based on the degree of complementarity miRNAs have recently been shown to play pivotal roles in diverse developmental and cellular processes and linked to a variety of skin diseases and cancers In the present study the expression profiles for the two most important miRNA processing enzymes Dicer and Drosha of actinic keratoses basal cell carcinoma and squamous cell carcinoma are compared to healthy skin tissue
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None