Ignite Creation Date:
2024-05-05 @ 9:18 PM
Last Modification Date:
2024-10-26 @ 10:02 AM
Study NCT ID:
NCT00854958
Status:
COMPLETED
Last Update Posted:
2009-03-03
First Post:
2009-03-02
Brief Title:
The Diagnosis of Oral Allergy Syndrome Through the Use of a Structured Questionnaire
Sponsor:
Royal Brompton Harefield NHS Foundation Trust
Organization:
Royal Brompton Harefield NHS Foundation Trust
Study Overview
Official Title:
The Diagnosis of Oral Allergy Syndrome Through the Use of a Structured Questionnaire
Status:
COMPLETED
Status Verified Date:
2009-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Oral allergy syndrome is a type of food allergy which mainly affects people with springtime hay fever It is caused by a cross-reaction between antibodies to pollens usually birch tree pollen and allergens in many different plant foods It is characterised by symptoms of itching andor swelling in the mouth andor throat when eating certain fruits vegetables and nuts Many of the allergens causing OAS are destroyed by heat making allergy testing using traditional allergen extracts unreliable Prick testing or challenging with fresh foods is more reliable but time consuming inconvenient and largely unavailable Pilot study results suggest the characteristic symptoms and foods involved in OAS allow accurate diagnosis using clinical history alone which forms the basis for the hypothesis of this proposal that OAS can be diagnosed accurately by use of a validated questionnaire alone The diagnostic questionnaire PFSDQ revised from the results of the pilot study will be tested against two reference test methods the gold standard of oral food challenge and the platinum standard of diagnosis made by a medical expert based on history skin prick testing and oral food challenge This is not an epidemiological study but with no published studies on OAS in a UK population this study will also provide some information on the prevalence of OAS in those with springtime hayfever in the UK
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None