Ignite Creation Date:
2025-12-24 @ 11:11 PM
Ignite Modification Date:
2026-01-01 @ 8:18 AM
Study NCT ID:
NCT01987869
Status:
UNKNOWN
Last Update Posted:
2013-11-19
First Post:
2013-11-13
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Hiperemezis and Serotonin Elevated Serum Serotonin Levels in Hyperemesis
Sponsor:
Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Organization:
Study Overview
Official Title:
Relationship Between Elevated Serum Serotonin Levels in Symptomatic Patients With Hyperemezis
Status:
UNKNOWN
Status Verified Date:
2013-11
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Serotonin excretion was investigated in the nausea and vomiting associated with hiperemezis gravid arum.
Detailed Description:
The occurrence of severe nausea and vomiting of early pregnancy (hiperemezis gravid arum) is estimated between 0.3% to 1% of all pregnancies. Although hiperemezis gravid arum has been recognized for a long time, its pathophysiologic mechanisms are still poorly understood. Many theories have been advocated, but to date none of these have been convincing.
It has been demonstrated that the nausea and vomiting associated with increased in serotonin liberation. This has provided a rationale for the treatment of these symptoms with specific serotonin antagonists.
The aim of this trial was to investigate the possible relationship between hiperemezis gravid arum and serotonin liberation.
It has been demonstrated that the nausea and vomiting associated with increased in serotonin liberation. This has provided a rationale for the treatment of these symptoms with specific serotonin antagonists.
The aim of this trial was to investigate the possible relationship between hiperemezis gravid arum and serotonin liberation.
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: