Ignite Creation Date:
2024-05-05 @ 10:00 AM
Last Modification Date:
2024-10-26 @ 9:05 AM
Study NCT ID:
NCT00005371
Status:
COMPLETED
Last Update Posted:
2016-05-13
First Post:
2000-05-25
Brief Title:
Epidemiology of Acute Phase Protein and CHD
Sponsor:
National Heart Lung and Blood Institute NHLBI
Organization:
National Heart Lung and Blood Institute NHLBI
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2005-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To use the Multiple Risk Factor Intervention Trial MRFIT stored serum bank to do nested case-control studies of various serum risk factors in coronary heart disease incidence and mortality
Detailed Description:
BACKGROUND
The use of stored serum from the MRFIT cohort contributed additional information on how various lipid fractions and other serum constituents interact to produce atherosclerotic disease The cost of performing such studies on a new cohort would be many times greater
DESIGN NARRATIVE
The case-control study evaluated 1 the relationship between acute phase reactants albumin alpha 1 glycoprotein c-reactive protein and sialic acid 2 oxidized low density lipoprotein cholesterol LDLC measured by thiobarbituric acid reactive substances TBARS and risk of myocardial infarction or coronary heart disease death 3 Lpa 4 antioxidized vitamin E and carotene The study was done in one year because of the need to analyze the specimens shortly after they were thawed The statistical analysis was done in collaboration with University of Minnesota Coordinating Center
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
The use of stored serum from the MRFIT cohort contributed additional information on how various lipid fractions and other serum constituents interact to produce atherosclerotic disease The cost of performing such studies on a new cohort would be many times greater
DESIGN NARRATIVE
The case-control study evaluated 1 the relationship between acute phase reactants albumin alpha 1 glycoprotein c-reactive protein and sialic acid 2 oxidized low density lipoprotein cholesterol LDLC measured by thiobarbituric acid reactive substances TBARS and risk of myocardial infarction or coronary heart disease death 3 Lpa 4 antioxidized vitamin E and carotene The study was done in one year because of the need to analyze the specimens shortly after they were thawed The statistical analysis was done in collaboration with University of Minnesota Coordinating Center
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R01HL049872 | NIH | None | httpsreporternihgovquickSearchR01HL049872 |