Ignite Creation Date:
2025-12-17 @ 4:13 PM
Ignite Modification Date:
2025-12-23 @ 11:48 PM
Study NCT ID:
NCT00742456
Status:
COMPLETED
Last Update Posted:
2011-02-23
First Post:
2008-08-26
Is Possible Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Microvascular Dilatation After Endogenous Induced Hyperinsulinemia
Sponsor:
Maastricht University Medical Center
Organization:
Study Overview
Official Title:
Insulin-induced Microvascular Dilatation During a Physiological Stimulus - Studies in Hypertension and Obesity.
Status:
COMPLETED
Status Verified Date:
2011-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
In this study we will examine if the insulin-induced microvascular effects will occur after a physiological stimulus (i.e. a oral glucose tolerance test). With that the physiological importance of the insulin-induced microvascular dilatation can be elucidated. In this study we hypothesize that oral glucose intake and consequently the endogenous induced hyperinsulinemia will lead to insulin-induced microvascular dilatation in healthy normotensive subjects. Furthermore, we suggest that the insulin-mediated microvascular dilatation, resulting from this physiological induced hyperinsulinemia, will be less in hypertensive and obese subjects compared to healthy controls.
Detailed Description:
None
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: