Ignite Creation Date:
2025-12-24 @ 11:33 PM
Ignite Modification Date:
2026-01-04 @ 3:57 PM
Study NCT ID:
NCT05044156
Status:
COMPLETED
Last Update Posted:
2022-03-08
First Post:
2021-09-04
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Investigation of the Relationship Between Salivary Histatine-5 Level and Vaginal Candidiasis in Women
Sponsor:
Usak State Hospital
Organization:
Study Overview
Official Title:
Investigation of the Relationship Between Salivary Histatine-5 Level and Vaginal Candidiasis in Women
Status:
COMPLETED
Status Verified Date:
2022-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The low Histatine-5 (HST-5) level of the saliva can lead to vaginal candidiasis. Because HST-5 level in the saliva can effect vaginal Ph, flora and local defence mechanisms.
Histatine-5 is secreted in the parotis and submandibular glands. İt riches histidine amino ascid and have antifungal activity. Salivary proteins and their plasma levels were found as similar in the literature.
Histatine-5 is secreted in the parotis and submandibular glands. İt riches histidine amino ascid and have antifungal activity. Salivary proteins and their plasma levels were found as similar in the literature.
Detailed Description:
Women with regularly menstrual cycle will enroll in the study than will separate two groups:
Study group: women with vaginal candidiasis ( diagnosed by clinic and lab.)
Control group: women ( not have any vaginal infections candida and others)
Saliva samples will be taken from two groups than HST-5 level will be analyzed. Finally HST-5 levels of the two groups will be compared .
Women with diabetes, immun deficiency, pregnancy, virgin, menopausal period , premature ovarian failure will be excluded.
Study group: women with vaginal candidiasis ( diagnosed by clinic and lab.)
Control group: women ( not have any vaginal infections candida and others)
Saliva samples will be taken from two groups than HST-5 level will be analyzed. Finally HST-5 levels of the two groups will be compared .
Women with diabetes, immun deficiency, pregnancy, virgin, menopausal period , premature ovarian failure will be excluded.
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: