Ignite Creation Date:
2025-12-24 @ 11:42 PM
Ignite Modification Date:
2025-12-25 @ 9:33 PM
Study NCT ID:
NCT00099151
Status:
COMPLETED
Last Update Posted:
2009-12-11
First Post:
2004-12-08
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
CALERIE (PBRC, Baton Rouge) - Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy
Sponsor:
National Institute on Aging (NIA)
Organization:
Study Overview
Official Title:
Metabolic Adaptations to Six Month Caloric Restriction
Status:
COMPLETED
Status Verified Date:
2004-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study is one of three CALERIE trials that test the hypothesis that a reduced calorie, nutritionally sound diet improves biomarkers of aging and prevents some age-related chronic diseases such as cancer, diabetes, and cardiovascular disease. The three sites that are participating in the CALERIE trial represent a diversity of subject populations and interventional strategies.
Detailed Description:
This study tests whether chronic caloric restriction improves risk factors of longevity in humans as it is known to do in animals, by measuring a variety of factors dealing with metabolism and oxidative stress, through physical evaluations and laboratory tests.
Participants will receive dietary counseling and free medical evaluations. In addition, each volunteer will be asked to do one of the following:
1. Follow a reduced calorie diet
2. Follow a reduced calorie diet using a liquid diet
3. Increase physical activity while on a reduced calorie diet
4. Follow a standard diet.
Three separate five-day inpatient stays are required.
Participants will receive dietary counseling and free medical evaluations. In addition, each volunteer will be asked to do one of the following:
1. Follow a reduced calorie diet
2. Follow a reduced calorie diet using a liquid diet
3. Increase physical activity while on a reduced calorie diet
4. Follow a standard diet.
Three separate five-day inpatient stays are required.
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary ID Infos
| Secondary ID | Type | Domain | Link | View |
|---|---|---|---|---|
| 5U01AG020478-02 | NIH | None | https://reporter.nih.gov/quic… | View |