Ignite Creation Date:
2024-05-05 @ 11:26 AM
Last Modification Date:
2024-10-26 @ 9:08 AM
Study NCT ID:
NCT00048815
Status:
COMPLETED
Last Update Posted:
2018-05-11
First Post:
2002-11-08
Brief Title:
Drug Therapy to Treat Minor Depression
Sponsor:
Massachusetts General Hospital
Organization:
Massachusetts General Hospital
Study Overview
Official Title:
Pharmacotherapy for Minor Depression
Status:
COMPLETED
Status Verified Date:
2018-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This 6-month study will compare the effectiveness of citalopram Celexa hypericum St Johns Wort and placebo for the treatment of minor depression
Detailed Description:
Minor depression is highly prevalent causes substantial morbidity and disability presents a serious risk factor for the development of major depressive disorder yet is under recognized and under treated Researchers have determined that patients with minor depression frequently seek treatment from general practitioners and are often treated with prescription antidepressants There is a need to evaluate the effectiveness of St Johns Wort in the management of minor depression If the proposed study demonstrates the efficacy of St Johns Wort andor citalopram it will suggest treatment paradigms that can be tested and applied in primary care settings
Subjects participated in a 12-week double-blind randomized study comparing St Johns Wort citalopram and placebo Subjects were recruited through clinical referrals and community advertising Data were obtained at the baseline visit just prior to randomization and at postrandomization visits conducted at 2-week intervals for the next 12 weeks for a modified intent-to-treat sample consisting of all 73 subjects with at least 1 post-randomization visit evaluable sample
Subjects participated in a 12-week double-blind randomized study comparing St Johns Wort citalopram and placebo Subjects were recruited through clinical referrals and community advertising Data were obtained at the baseline visit just prior to randomization and at postrandomization visits conducted at 2-week intervals for the next 12 weeks for a modified intent-to-treat sample consisting of all 73 subjects with at least 1 post-randomization visit evaluable sample
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| DSIR AT-SO | US NIH GrantContract | None | httpsreporternihgovquickSearchR01MH061394 |
| R01MH061758 | NIH | None | None |
| R01MH061757 | NIH | None | None |
| R01MH061394 | NIH | None | None |