Ignite Creation Date:
2025-12-26 @ 10:43 PM
Ignite Modification Date:
2025-12-26 @ 10:43 PM
Study NCT ID:
NCT00613912
Status:
COMPLETED
Last Update Posted:
2011-11-21
First Post:
2008-01-31
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Advanced MRI in Major Depression
Sponsor:
University of Aarhus
Organization:
Study Overview
Official Title:
Advanced MRI at 3T for the Evaluation of Ambulant Patients With Major Depression
Status:
COMPLETED
Status Verified Date:
2011-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Depression is the most common psychiatric disorder.
* 3-5% of a given population has major depression.
* Less than 50% of the depressed in Denmark are diagnosed with major depression.
* 25-50% of the depressed have a relative with major depression-underlying brain pathology?
The purpose of this study is to use MRI to evaluate cerebral morphology and function in ambulant patients with major depression
* 3-5% of a given population has major depression.
* Less than 50% of the depressed in Denmark are diagnosed with major depression.
* 25-50% of the depressed have a relative with major depression-underlying brain pathology?
The purpose of this study is to use MRI to evaluate cerebral morphology and function in ambulant patients with major depression
Detailed Description:
Previous studies within major depression, have often included hospitalized patients with severe symptoms and imaging have been performed with PET and SPECT, which uses ionizing radiation. This study focus on ambulant patients(with or without medication/ECT treatment), to find patients in an earlier stage. Cerebral perfusion with the MR sequence Arterial Spin Labelling, concentrations of different metabolites with MR spectroscopy and brain volumetry with BRAVO 3D T1 ax will be performed.
MR protocol: T2 sag, T2 FLAIR ax, ASL ax, MRS and 3D T1 ax. Scan time 45 min.
MR protocol: T2 sag, T2 FLAIR ax, ASL ax, MRS and 3D T1 ax. Scan time 45 min.
Study Oversight
Has Oversight DMC:
True
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: