Ignite Creation Date:
2024-05-05 @ 10:10 PM
Last Modification Date:
2024-10-26 @ 10:14 AM
Study NCT ID:
NCT01041313
Status:
UNKNOWN
Last Update Posted:
2010-06-29
First Post:
2009-12-29
Brief Title:
Memantine for Post-Operative Pain Control
Sponsor:
University of Washington
Organization:
University of Washington
Study Overview
Official Title:
Memantine for Post-Operative Pain Control
Status:
UNKNOWN
Status Verified Date:
2010-06
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Pain is a common element of surgery Opiates morphine oxycodone hydrocodone methadone fentanyl are very helpful in decreasing pain after surgery Unfortunately with repeated use opiates lose their effectiveness such that patients need to utilize more opiates to achieve adequate pain relief - a phenomenon called tolerance Sometimes tolerance to a pain relievers effects can develop in just a few hours It is thought that activation of the N-methyl d-aspartate NMDA receptor a switch found on the surface of nerves is partially responsible for opiate tolerance Memantine is a medication that limits the activity of NMDA receptors in the brain and spinal cord It has been used for years to help patients with Alzheimers Disease In this study we will study the effects of memantine when combined with opiate medications to see whether it can increase the effectiveness of opiates for pain after surgery and reduce the side effects caused by opiates eg sedation nausea itching
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| NAM-MD-63 | None | None | None |