Ignite Creation Date:
2024-05-05 @ 11:28 AM
Last Modification Date:
2024-10-26 @ 9:07 AM
Study NCT ID:
NCT00044798
Status:
COMPLETED
Last Update Posted:
2013-09-27
First Post:
2002-09-04
Brief Title:
Magnetic Stimulation Therapy for Treating Vascular Depression
Sponsor:
University of Iowa
Organization:
University of Iowa
Study Overview
Official Title:
Vascular Depression and Magnetic Stimulation Therapy
Status:
COMPLETED
Status Verified Date:
2013-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
rtms
Brief Summary:
This 12-week study will evaluate the effectiveness of repetitive transcranial magnetic stimulation rTMS of the brain followed by citalopram Celexa for treatment of depression associated with small vascular lesions in the brain vascular depression
Detailed Description:
Vascular depression is a condition that typically affects the elderly and is associated with small vascular lesions It is more resistant to treatment and has a poorer outcome than nonvascular depression By altering excitability in the cortical area of the brain rTMS may be an effective treatment neuropsychiatric conditions particularly depression
Participants in this study will be randomly assigned to 15 treatments of either rTMS or sham rTMS for 3 weeks Following treatment participants will receive citalopram for 9 weeks Response rates to treatment relapse rates the size number and location of the vascular lesions and the amount of regional brain atrophy will be measured Improvements in activities of daily living quality of life and cognitive function will also be also measured
Participants in this study will be randomly assigned to 15 treatments of either rTMS or sham rTMS for 3 weeks Following treatment participants will receive citalopram for 9 weeks Response rates to treatment relapse rates the size number and location of the vascular lesions and the amount of regional brain atrophy will be measured Improvements in activities of daily living quality of life and cognitive function will also be also measured
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| DATR A4-GPX | US NIH GrantContract | None | httpsreporternihgovquickSearchR01MH063405 |
| R01MH063405 | NIH | None | None |