Viewing Study NCT00050869



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Last Modification Date: 2024-10-26 @ 9:08 AM
Study NCT ID: NCT00050869
Status: COMPLETED
Last Update Posted: 2017-07-02
First Post: 2002-12-27

Brief Title: Learning a Motor Task Through Observation
Sponsor: National Institute of Neurological Disorders and Stroke NINDS
Organization: National Institutes of Health Clinical Center CC

Study Overview

Official Title: Encoding a Motor Memory by Action Observation
Status: COMPLETED
Status Verified Date: 2007-11-15
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: Motor training results in use dependent plasticity UDP thought to underlie recovery of motor function after brain injury The purpose of this protocol is to determine a if movement observation results in encoding of a motor memory in the primary motor cortex and b if observation of motor training can enhance the effects of physical training in healthy volunteers If so this may become an important tool in rehabilitative treatment for patients who are unable or partially able to train We will test our hypotheses by means of focal single pulse transcranial magnetic stimulation TMS in a group of healthy volunteers Our outcome measure will be the change in TMS-evoked movement direction as a function of training strategy So far we found that this is the case in healthy volunteers see data in analysis of the study The purpose of this amendment is to determine if action observation can elicit the same effects in adult chronic ischemic stroke patients who have had originally significant motor weakness but recovered to the point of being able to perform the motor tasks possibly resulting in a useful rehabilitative strategy
Detailed Description: Motor training results in use dependent plasticity UDP thought to underlie recovery of motor function after brain injury The purpose of this protocol is to determine a if movement observation results in encoding of a motor memory in the primary motor cortex and b if observation of motor training can enhance the effects of physical training in healthy volunteers If so this may become an important tool in rehabilitative treatment for patients who are unable or partially able to train We will test our hypotheses by means of focal single pulse transcranial magnetic stimulation TMS in a group of healthy volunteers Our outcome measure will be the change in TMS-evoked movement direction as a function of training strategy So far we found that this is the case in healthy volunteers see data in analysis of the study The purpose of this protocol is to determine if action observation can elicit the same effects in adult chronic ischemic stroke patients who have had originally significant motor weakness but recovered to the point of being able to perform the motor tasks possibly resulting in a useful rehabilitative strategy

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: None
Is a FDA Regulated Device?: None
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None
Secondary IDs
Secondary ID Type Domain Link
03-N-0074 None None None