Ignite Creation Date:
2025-12-25 @ 12:23 AM
Ignite Modification Date:
2026-03-03 @ 3:54 AM
Study NCT ID:
NCT07237958
Status:
COMPLETED
Last Update Posted:
2025-11-20
First Post:
2025-07-04
Is Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Effects on the Olfactory Epithelium and the Olfactory Nerve From Exposure to Diesel Exhaust
Sponsor:
Umeå University
Organization:
Study Overview
Official Title:
Effects on the Olfactory Epithelium in the Nose and the Olfactory Nerve (Nervus Olfactorius) From Exposure to Diesel Exhaust
Status:
COMPLETED
Status Verified Date:
2025-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
DINOSE
Brief Summary:
The goal of this study is to study the effect exposure to air pollution and its effect on development of dementia.
Does the diesel exhaust change the function of the olfactory system?
Have the exposures measurable effects on the sense of smell and cognitive ability?
Forty people are exposed to diesel exhaust exhaust and filtered air. The exposures are blinded and in a randomized order. Both groups undergo biopsies of the olfactory epithelium in the nose under local anesthesia after the exposures and after performing cognitive test.
Does the diesel exhaust change the function of the olfactory system?
Have the exposures measurable effects on the sense of smell and cognitive ability?
Forty people are exposed to diesel exhaust exhaust and filtered air. The exposures are blinded and in a randomized order. Both groups undergo biopsies of the olfactory epithelium in the nose under local anesthesia after the exposures and after performing cognitive test.
Detailed Description:
None
Study Oversight
Has Oversight DMC:
True
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
Secondary ID Infos
| Secondary ID | Type | Domain | Link | View |
|---|---|---|---|---|
| x | OTHER_GRANT | The Swedish Research Council | View |