Ignite Creation Date:
2024-05-05 @ 11:29 AM
Last Modification Date:
2024-10-26 @ 9:08 AM
Study NCT ID:
NCT00051324
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
2023-12-19
First Post:
2003-01-08
Brief Title:
Neurobiological Predictors of Huntingtons Disease PREDICT-HD
Sponsor:
University of Iowa
Organization:
University of Iowa
Study Overview
Official Title:
Neurobiological Predictors of Huntingtons Disease Trial
Status:
ACTIVE_NOT_RECRUITING
Status Verified Date:
2023-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
PREDICT-HD
Brief Summary:
The purpose of this trial is to study early brain and behavioral changes in people who have the gene expansion for Huntingtons disease but are currently healthy and have no symptoms
Detailed Description:
Huntingtons Disease HD is an inherited disease that causes changes in a persons ability to control movements thinking and feelings The intent of this study is to learn more about the beginning changes in thinking skills emotional regulation and brain structure and function as a person begins the transition from health to HD
Preliminary studies indicate that people with HD may have marked decline before an actual diagnosis This study will help reveal the earliest indicators of the disease and what factors influence the age at which a person carrying the gene develops the disease It is necessary to get information on the early stages of HD in order to develop drugs that can slow or postpone the onset of HD The investigators hope this study will provide essential information for future trials of experimental drugs for HD
During this study participants will undergo several detailed tests including MRI scans of the brain cognitive assessments physical exams bio specimen blood urine cerebral spinal fluid collection and neurological and psychiatric testing
Preliminary studies indicate that people with HD may have marked decline before an actual diagnosis This study will help reveal the earliest indicators of the disease and what factors influence the age at which a person carrying the gene develops the disease It is necessary to get information on the early stages of HD in order to develop drugs that can slow or postpone the onset of HD The investigators hope this study will provide essential information for future trials of experimental drugs for HD
During this study participants will undergo several detailed tests including MRI scans of the brain cognitive assessments physical exams bio specimen blood urine cerebral spinal fluid collection and neurological and psychiatric testing
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R01NS040068 | NIH | None | httpsreporternihgovquickSearchR01NS040068 |