Ignite Creation Date:
2024-05-05 @ 11:30 AM
Last Modification Date:
2024-10-26 @ 9:08 AM
Study NCT ID:
NCT00063544
Status:
WITHDRAWN
Last Update Posted:
2016-05-26
First Post:
2003-06-30
Brief Title:
Physical Activity and Childhood Obesity
Sponsor:
Anna Brooke
Organization:
University of Bristol
Study Overview
Official Title:
Physical Activity and Childhood Obesity
Status:
WITHDRAWN
Status Verified Date:
2016-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
CI left institution
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To measure associations between physical activity and obesity in a large population-based cohort of children
Detailed Description:
BACKGROUND
Childhood obesity is rapidly increasing in many countries and environmental factors are the main cause The onset of puberty may be a critical period Diet and physical activity are likely to be prime causative factors although the relative role of each may vary between children of differing age gender and ethnicity There are also likely to be many psychosocial and social-demographic factors that can confound these relationships and these confounders may vary between sub-groups There continues to be uncertainty regarding the role of these factors and their differential effects in subgroups of the population It is crucial to develop a better understanding of how dietary and physical activity patterns affect energy balance and how these characteristics interact with other factors
Measures of physical activity will be added to ongoing assessments of boys and girls n10000 participating in the Avon Longitudinal Study of Parents and Children ALSPAC This comprehensive study has been following children and their parents for about 9-10 years The study has an extensive database including maternal and paternal social background lifestyle and habits including diet and physical activity medical history and medications during pregnancy and thereafter ALSPAC has also collected and retained biological samples including maternal blood urine cord blood umbilical cord placenta hair and nail clippings deciduous teeth childs blood and DNA Data on the mothers also include details of her own parents lifestyle her childhood lifestyle occupation history and diet and access to mothers biological samples Over 71 of the cohort 10000 of 14541 participants have been retained
DESIGN NARRATIVE
Levels and patterns of physical activity will be measured on all children at ages 11 and 13 to assess relationships with measures of obesity Physical activity will be measured objectively for 5 days The data together with other data collected during pregnancy infancy and childhood will be used to investigate relationships between modes intensities quantities and patterns of physical activity and the development of obesity at this critical stage of life The strengths of this prospective study are its size high retention rates and the extensive set of whole-of-life measures already taken on the children With over 10000 children expected to attend annually for health checks throughout adolescence the study will be adequately powered to quantify associations between physical activity and obesity The study of physical activity in children has to date been seriously restricted because of high levels of measurement error inherent in all self-report measures of physical activity In this study physical activity will be measured using a single-plane accelerometer CSA model 7164 - a small lightweight electronic motion sensor attached to the childs belt for a period of 5 days This instrument gives the capacity to to characterize childrens physical activity and inactivity more accurately than ever before Comprehensive measurements of diet and body composition principally Dual-emission X-ray Absorptiometry - DXA will also be taken at ages 11 and 13 under separate funding
Childhood obesity is rapidly increasing in many countries and environmental factors are the main cause The onset of puberty may be a critical period Diet and physical activity are likely to be prime causative factors although the relative role of each may vary between children of differing age gender and ethnicity There are also likely to be many psychosocial and social-demographic factors that can confound these relationships and these confounders may vary between sub-groups There continues to be uncertainty regarding the role of these factors and their differential effects in subgroups of the population It is crucial to develop a better understanding of how dietary and physical activity patterns affect energy balance and how these characteristics interact with other factors
Measures of physical activity will be added to ongoing assessments of boys and girls n10000 participating in the Avon Longitudinal Study of Parents and Children ALSPAC This comprehensive study has been following children and their parents for about 9-10 years The study has an extensive database including maternal and paternal social background lifestyle and habits including diet and physical activity medical history and medications during pregnancy and thereafter ALSPAC has also collected and retained biological samples including maternal blood urine cord blood umbilical cord placenta hair and nail clippings deciduous teeth childs blood and DNA Data on the mothers also include details of her own parents lifestyle her childhood lifestyle occupation history and diet and access to mothers biological samples Over 71 of the cohort 10000 of 14541 participants have been retained
DESIGN NARRATIVE
Levels and patterns of physical activity will be measured on all children at ages 11 and 13 to assess relationships with measures of obesity Physical activity will be measured objectively for 5 days The data together with other data collected during pregnancy infancy and childhood will be used to investigate relationships between modes intensities quantities and patterns of physical activity and the development of obesity at this critical stage of life The strengths of this prospective study are its size high retention rates and the extensive set of whole-of-life measures already taken on the children With over 10000 children expected to attend annually for health checks throughout adolescence the study will be adequately powered to quantify associations between physical activity and obesity The study of physical activity in children has to date been seriously restricted because of high levels of measurement error inherent in all self-report measures of physical activity In this study physical activity will be measured using a single-plane accelerometer CSA model 7164 - a small lightweight electronic motion sensor attached to the childs belt for a period of 5 days This instrument gives the capacity to to characterize childrens physical activity and inactivity more accurately than ever before Comprehensive measurements of diet and body composition principally Dual-emission X-ray Absorptiometry - DXA will also be taken at ages 11 and 13 under separate funding
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R01HL071248 | NIH | None | httpsreporternihgovquickSearchR01HL071248 |