Ignite Creation Date:
2024-05-05 @ 10:00 AM
Last Modification Date:
2024-10-26 @ 9:03 AM
Study NCT ID:
NCT00002924
Status:
COMPLETED
Last Update Posted:
2016-07-14
First Post:
1999-11-01
Brief Title:
Gene Mutations in Patients With Advanced Prostate Cancer That Is Not Responsive to Hormone Therapy
Sponsor:
Alliance for Clinical Trials in Oncology
Organization:
Alliance for Clinical Trials in Oncology
Study Overview
Official Title:
Androgen Receptor Mutations in Hormone Refractory Prostate Cancer
Status:
COMPLETED
Status Verified Date:
2016-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
RATIONALE Gene mutations may make prostate cancer cells unable to attach to androgens This may permit the growth of prostate cancer Gene testing may improve the identification of patients with advanced prostate cancer
PURPOSE Clinical trial to study the androgen receptor gene in patients with prostate cancer that is not responsive to hormone therapy
PURPOSE Clinical trial to study the androgen receptor gene in patients with prostate cancer that is not responsive to hormone therapy
Detailed Description:
OBJECTIVES
1 the feasibility of collecting bone marrow biopsies from prostate cancer patients in a cooperative group setting
2 the incidence of marrow invasion by prostate tumor in random bone marrow biopsy
3 the influence of previous prostate radiation on obtaining prostate tumor
4 the frequency and type of AR mutations and
5 association of AR mutations with response to antiandrogen withdrawal
1 the feasibility of collecting bone marrow biopsies from prostate cancer patients in a cooperative group setting
2 the incidence of marrow invasion by prostate tumor in random bone marrow biopsy
3 the influence of previous prostate radiation on obtaining prostate tumor
4 the frequency and type of AR mutations and
5 association of AR mutations with response to antiandrogen withdrawal
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| CDR0000065329 | REGISTRY | NCI Physician Data Query | httpsreporternihgovquickSearchU10CA031946 |
| U10CA031946 | NIH | None | None |