Ignite Creation Date:
2024-05-05 @ 11:06 PM
Last Modification Date:
2024-10-26 @ 10:28 AM
Study NCT ID:
NCT01252901
Status:
COMPLETED
Last Update Posted:
2015-05-28
First Post:
2010-12-01
Brief Title:
Registry for Patients With Wilms Tumor Suppressor Gene 1 WT1 Mutation Associated Diseases
Sponsor:
Universitätsklinikum Hamburg-Eppendorf
Organization:
Universitätsklinikum Hamburg-Eppendorf
Study Overview
Official Title:
Registry for Patients With WT1 Mutation Associated Diseases
Status:
COMPLETED
Status Verified Date:
2015-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The Wilms tumor suppressor gene 1 WT1 encodes for a transcription factor which plays an important role during urogenital development Patients carrying a WT1 germline mutation show symptoms like proteinuria Wilms tumors genital malformations and kidney failure Milder variants are possible and classification is not always possible In this registry we are collecting detailed clinical data of affected individuals to establish genotype-phenotype correlations with the greater goal to optimize patient care
Detailed Description:
The Wilms tumor suppressor gene 1 WT1 encodes for a transcription factor which plays an important role during urogenital development Patients carrying a WT1 germline mutation show symptoms like proteinuria Wilms tumors genital malformations and kidney failure which usually occur in early childhood Milder variants are possible and classification as one of the three rare syndromes associated with WT1 mutations Denys-Drash syndrome Frasier syndrome or WAGR syndrome is not always possible In this registry we are collecting detailed clinical data of affected individuals to establish genotype-phenotype correlations with the greater goal to optimize patient care
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None