Ignite Creation Date:
2024-05-05 @ 11:32 AM
Last Modification Date:
2024-10-26 @ 9:09 AM
Study NCT ID:
NCT00071162
Status:
UNKNOWN
Last Update Posted:
2009-04-01
First Post:
2003-10-14
Brief Title:
Genetics of Fibromyalgia
Sponsor:
National Institute of Arthritis and Musculoskeletal and Skin Diseases NIAMS
Organization:
National Institute of Arthritis and Musculoskeletal and Skin Diseases NIAMS
Study Overview
Official Title:
Fibromyalgia Family Study Registry
Status:
UNKNOWN
Status Verified Date:
2009-03
Last Known Status:
ACTIVE_NOT_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The Fibromyalgia Family Study identifies and collects blood samples from families with two or more members affected with Fibromyalgia Syndrome FMS The primary goal of the study is to identify genes that predispose people to FMS andor symptoms related to FMS identifying these genes may lead to a better understanding of the disease and more effective treatments
Detailed Description:
FMS predominantly affects women and is characterized by chronic widespread musculoskeletal pain fatigue sleep disturbance and multiple tender points on physical examination The pathophysiological mechanisms underlying FMS are not clearly understood but neuroendocrine factors seem to be of major importance Studies of familial association suggest that genetic factors play a role in FMS This study will establish patterns of genetic linkage in families with FMS
Participating family members will undergo a brief physical exam including tender point exam donate a blood sample and complete a detailed questionnaire that includes experience with pain fatigue depression bowel symptoms headache anxiety and physical limitations Measurements of serum serotonin and related compounds will also be obtained To detect genetic factors a genome-wide linkage scan using 405 microsatellite markers will be performed
Participating family members will undergo a brief physical exam including tender point exam donate a blood sample and complete a detailed questionnaire that includes experience with pain fatigue depression bowel symptoms headache anxiety and physical limitations Measurements of serum serotonin and related compounds will also be obtained To detect genetic factors a genome-wide linkage scan using 405 microsatellite markers will be performed
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None