Ignite Creation Date:
2024-05-05 @ 11:32 AM
Last Modification Date:
2024-10-26 @ 9:09 AM
Study NCT ID:
NCT00071175
Status:
COMPLETED
Last Update Posted:
2017-09-18
First Post:
2003-10-14
Brief Title:
Lupus Genetics Studies
Sponsor:
Oklahoma Medical Research Foundation
Organization:
Oklahoma Medical Research Foundation
Study Overview
Official Title:
Lupus Genetic Studies Lupus Family Registry Repository
Status:
COMPLETED
Status Verified Date:
2017-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
LFRR
Brief Summary:
The Lupus Genetics Studies and Lupus Family Registry Repository are working to find the genes that reveal the causes of systemic lupus erythematosus SLE or lupus The study is enrolling families of all ethnic backgrounds from the United States Canada Puerto Rico and the Virgin Islands that have one or more living members diagnosed with SLE
Detailed Description:
SLE is an often crippling and potentially fatal autoimmune disease that is nine times more prevalent in women than in men and four times more likely to affect African American females than Caucasian females It is suspected that a genetic predisposition along with environmental factors contribute to the clinical manifestation of SLE The Lupus Genetics Studies consist of several familial SLE studies including the Lupus Family Registry Repository LFRR formerly known as the Lupus Multiplex Registry Repository or LMRR The Lupus Studies enroll families of all ethnicities with one or more members diagnosed with systemic lupus to determine what genes contribute to the development of the disease
Additionally the Lupus Family Registry Repository is the largest repository of its kind in North America In addition to the research done on site the Repository serves as a national resource for scientists interested in conducting research on SLE and families either simplex or multiplex for lupus Data serum samples and DNA samples are available to researchers By collecting families in which two or more living individuals have been diagnosed with SLE the study is utilizing the genetic link between the affected family members to discover disease-associated genes
Records will be requested from the patients treating physicians to document various lupus symptoms and related problems One-time blood samples will be collected from the patients as well as from certain family members and an unrelated volunteer There is no cost to participate and the study pays for sample draws and shipping
Additionally the Lupus Family Registry Repository is the largest repository of its kind in North America In addition to the research done on site the Repository serves as a national resource for scientists interested in conducting research on SLE and families either simplex or multiplex for lupus Data serum samples and DNA samples are available to researchers By collecting families in which two or more living individuals have been diagnosed with SLE the study is utilizing the genetic link between the affected family members to discover disease-associated genes
Records will be requested from the patients treating physicians to document various lupus symptoms and related problems One-time blood samples will be collected from the patients as well as from certain family members and an unrelated volunteer There is no cost to participate and the study pays for sample draws and shipping
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| AR62277 | US NIH GrantContract | None | httpsreporternihgovquickSearch5P01AR049084-09 |
| 5P01AR049084-09 | NIH | None | None |
| AI24717 | None | None | None |
| AR42460 | None | None | None |
| AR049084 | None | None | None |
| AR52253 | None | None | None |