Ignite Creation Date:
2025-12-25 @ 4:17 AM
Ignite Modification Date:
2026-01-24 @ 7:52 AM
Study NCT ID:
NCT00289120
Status:
COMPLETED
Last Update Posted:
2016-06-08
First Post:
2006-02-07
Is NOT Gene Therapy:
True
Has Adverse Events:
True
Brief Title:
Effect of Cola on Urinary Stone Risk Factors
Sponsor:
Organization:
Raw JSON
{'hasResults': True, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D007669', 'term': 'Kidney Calculi'}, {'id': 'D052878', 'term': 'Urolithiasis'}], 'ancestors': [{'id': 'D053040', 'term': 'Nephrolithiasis'}, {'id': 'D007674', 'term': 'Kidney Diseases'}, {'id': 'D014570', 'term': 'Urologic Diseases'}, {'id': 'D052776', 'term': 'Female Urogenital Diseases'}, {'id': 'D005261', 'term': 'Female Urogenital Diseases and Pregnancy Complications'}, {'id': 'D000091642', 'term': 'Urogenital Diseases'}, {'id': 'D014545', 'term': 'Urinary Calculi'}, {'id': 'D052801', 'term': 'Male Urogenital Diseases'}, {'id': 'D002137', 'term': 'Calculi'}, {'id': 'D020763', 'term': 'Pathological Conditions, Anatomical'}, {'id': 'D013568', 'term': 'Pathological Conditions, Signs and Symptoms'}]}}, 'resultsSection': {'moreInfoModule': {'pointOfContact': {'email': 'kogan@emory.edu', 'phone': '404-778-4898', 'title': 'Kenneth Ogan', 'organization': 'Emory University'}, 'certainAgreement': {'piSponsorEmployee': False, 'restrictiveAgreement': False}}, 'adverseEventsModule': {'eventGroups': [{'id': 'EG000', 'title': 'Cola Beverage Phase', 'description': 'Subjects were given 500cc of Cola twice daily to be ingested with breakfast and dinner for six days while on a metabolic diet.\n\nThere will be a three weeks interval (wash out period) before crossover to the other treatment arm.\n\nNo adverse event reported.', 'otherNumAtRisk': 13, 'otherNumAffected': 0, 'seriousNumAtRisk': 13, 'seriousNumAffected': 0}, {'id': 'EG001', 'title': 'Deionized Water Drinking Phase', 'description': 'Subjects were given 500cc of regular deionized water twice daily to be ingested with breakfast and dinner for six days while on a metabolic diet.\n\nNo adverse event reported.', 'otherNumAtRisk': 13, 'otherNumAffected': 0, 'seriousNumAtRisk': 13, 'seriousNumAffected': 0}], 'frequencyThreshold': '0'}, 'outcomeMeasuresModule': {'outcomeMeasures': [{'type': 'PRIMARY', 'title': 'The Plasma and Urine Parameters', 'denoms': [{'units': 'Participants', 'counts': [{'value': '13', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Cola', 'description': 'they ingested 500 mL of cola (regular Publix brand©) twice daily, with breakfast and dinner.'}, {'id': 'OG001', 'title': 'Water', 'description': 'participants ingested 500 mL of deionized water twice daily, with breakfast and dinner.'}], 'classes': [{'title': 'Plasma Proteins', 'categories': [{'measurements': [{'value': '6800', 'spread': '500', 'groupId': 'OG000'}, {'value': '6800', 'spread': '500', 'groupId': 'OG001'}]}]}, {'title': 'Plasma Albumin', 'categories': [{'measurements': [{'value': '3700', 'spread': '300', 'groupId': 'OG000'}, {'value': '3700', 'spread': '300', 'groupId': 'OG001'}]}]}, {'title': 'Plasma Calcium', 'categories': [{'measurements': [{'value': '9.1', 'spread': '0.3', 'groupId': 'OG000'}, {'value': '9.0', 'spread': '0.2', 'groupId': 'OG001'}]}]}, {'title': 'Mean Plasma Glucose', 'categories': [{'measurements': [{'value': '92.8', 'spread': '9', 'groupId': 'OG000'}, {'value': '95.2', 'spread': '15.7', 'groupId': 'OG001'}]}]}, {'title': 'blood urea nitrogen', 'categories': [{'measurements': [{'value': '10.1', 'spread': '4.5', 'groupId': 'OG000'}, {'value': '11.1', 'spread': '5.0', 'groupId': 'OG001'}]}]}, {'title': 'Plasma Creatinine', 'categories': [{'measurements': [{'value': '0.9', 'spread': '0.2', 'groupId': 'OG000'}, {'value': '2.1', 'spread': '2.9', 'groupId': 'OG001'}]}]}, {'title': 'Urinary Calcium', 'categories': [{'measurements': [{'value': '124.3', 'spread': '74.5', 'groupId': 'OG000'}, {'value': '146.4', 'spread': '86.9', 'groupId': 'OG001'}]}]}, {'title': 'Urinary Magnesium', 'categories': [{'measurements': [{'value': '94.6', 'spread': '43.7', 'groupId': 'OG000'}, {'value': '106.8', 'spread': '49.9', 'groupId': 'OG001'}]}]}, {'title': 'Urinary Phosphets', 'categories': [{'measurements': [{'value': '720.7', 'spread': '224.1', 'groupId': 'OG000'}, {'value': '739.6', 'spread': '320.5', 'groupId': 'OG001'}]}]}, {'title': 'Urinary Creatinine', 'categories': [{'measurements': [{'value': '1620.1', 'spread': '699.0', 'groupId': 'OG000'}, {'value': '1950.1', 'spread': '1057.1', 'groupId': 'OG001'}]}]}, {'title': 'Urinary Citrate', 'categories': [{'measurements': [{'value': '475.9', 'spread': '240.6', 'groupId': 'OG000'}, {'value': '727.7', 'spread': '666.2', 'groupId': 'OG001'}]}]}, {'title': 'Urinary Oxalates', 'categories': [{'measurements': [{'value': '39.7', 'spread': '25.6', 'groupId': 'OG000'}, {'value': '34.7', 'spread': '21.0', 'groupId': 'OG001'}]}]}, {'title': 'Uric acids', 'categories': [{'measurements': [{'value': '555.3', 'spread': '183.1', 'groupId': 'OG000'}, {'value': '646.4', 'spread': '272.0', 'groupId': 'OG001'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'at the end of each 6-day intervention in Cola and Water Phase', 'description': 'The Plasma and Urine Parameters that were assessed at the end of cola and water (arms) phase:\n\nPlasma Parameters:\n\nCA (mg per dL) GLU (mg per dL) BUN (mg per dL) Cr (mg per dL) Prot (mg per dL) ALB (mg per dL)\n\nUrine Parameters:\n\nuCa (mg per dL) uMg (mg per dL) uP (mg per dL) uCr (mg per dL) uCit (mg per dL) uOx (mg per dL) uUA (mg per dL)\n\nThe parameters were consolidated into the one value as a mean of all the values in the phase or group (Table 3) and later for longitudinal analysis as a mean of all the values in the phase for each participant (Table 4).\n\nmeasure of dispersion was standard deviation.', 'unitOfMeasure': 'mg per dL', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED'}, {'type': 'PRIMARY', 'title': 'The Plasma and Urine Parameters', 'denoms': [{'units': 'Participants', 'counts': [{'value': '13', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Water', 'description': 'participants ingested 500 mL of deionized water twice daily, with breakfast and dinner.'}, {'id': 'OG001', 'title': 'Cola', 'description': 'they ingested 500 mL of cola (regular Publix brand©) twice daily, with breakfast and dinner.'}], 'classes': [{'title': 'Plasma sodium', 'categories': [{'measurements': [{'value': '138.3', 'spread': '2.5', 'groupId': 'OG000'}, {'value': '139.1', 'spread': '2.3', 'groupId': 'OG001'}]}]}, {'title': 'Plasma Potassium', 'categories': [{'measurements': [{'value': '3.8', 'spread': '0.2', 'groupId': 'OG000'}, {'value': '3.9', 'spread': '0.4', 'groupId': 'OG001'}]}]}, {'title': 'Plasma Chlorides', 'categories': [{'measurements': [{'value': '104.8', 'spread': '2.3', 'groupId': 'OG000'}, {'value': '105.2', 'spread': '3.0', 'groupId': 'OG001'}]}]}, {'title': 'Plasma CO2', 'categories': [{'measurements': [{'value': '26.1', 'spread': '2.0', 'groupId': 'OG000'}, {'value': '26.4', 'spread': '2.4', 'groupId': 'OG001'}]}]}, {'title': 'Plasma AG', 'categories': [{'measurements': [{'value': '7.3', 'spread': '1.2', 'groupId': 'OG000'}, {'value': '7.3', 'spread': '1.6', 'groupId': 'OG001'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'at the end of 6-day intervention of Cola and water phase', 'description': 'The Plasma and Urine Parameters that were assessed at the end of cola and water (arms) phase:\n\nPlasma Parameters:\n\nNa (mEq per L) K (mEq per L) CL (mEq per L) CO2(mEq per L) AG (mEq per L)\n\nThe parameters were consolidated into the one value as a mean of all the values in the phase or group (Table 3) and later for longitudinal analysis as a mean of all the values in the phase for each participant (Table 4).\n\nmeasure of dispersion was standard deviation.', 'unitOfMeasure': 'mEq/L', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED'}, {'type': 'PRIMARY', 'title': 'The Plasma Osmolarity', 'denoms': [{'units': 'Participants', 'counts': [{'value': '13', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Water', 'description': 'participants ingested 500 mL of deionized water twice daily, with breakfast and dinner.'}, {'id': 'OG001', 'title': 'Cola', 'description': 'they ingested 500 mL of cola (regular Publix brand©) twice daily, with breakfast and dinner.'}], 'classes': [{'categories': [{'measurements': [{'value': '276.5', 'spread': '4.8', 'groupId': 'OG000'}, {'value': '277.5', 'spread': '5.0', 'groupId': 'OG001'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'at the end of 6-day intervention of cola and water phase', 'description': 'The Plasma osmolarity that were assessed at the end of cola and water (arms) phase:\n\nPlasma Parameters:\n\nOSM (mOsm/L)\n\nThe parameters were consolidated into the one value as a mean of all the values in the phase or group (Table 3) and later for longitudinal analysis as a mean of all the values in the phase for each participant (Table 4).\n\nmeasure of dispersion was standard deviation.', 'unitOfMeasure': 'mOsm/L', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED'}, {'type': 'SECONDARY', 'title': 'Total Urine Volume', 'denoms': [{'units': 'Participants', 'counts': [{'value': '13', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Water', 'description': 'participants ingested 500 mL of deionized water twice daily, with breakfast and dinner.'}, {'id': 'OG001', 'title': 'Cola', 'description': 'they ingested 500 mL of cola (regular Publix brand©) twice daily, with breakfast and dinner.'}], 'classes': [{'categories': [{'measurements': [{'value': '2521.3', 'spread': '1152.6', 'groupId': 'OG000'}, {'value': '2266.2', 'spread': '811.0', 'groupId': 'OG001'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'at the end of each 6-day intervention in Cola and Water Phase', 'description': 'The Plasma and Urine Parameters that were assessed at the end of cola and water (arms) phase:\n\nUrine Parameters:\n\nTotal Urine Volume (mL/day)\n\nThe parameters were consolidated into the one value as a mean of all the values in the phase or group (Table 3) and later for longitudinal analysis as a mean of all the values in the phase for each participant (Table 4).\n\nmeasure of dispersion was standard deviation.', 'unitOfMeasure': 'mL/day', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED'}, {'type': 'SECONDARY', 'title': 'Urinary pH', 'denoms': [{'units': 'Participants', 'counts': [{'value': '13', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Cola', 'description': 'they ingested 500 mL of cola (regular Publix brand©) twice daily, with breakfast and dinner.'}, {'id': 'OG001', 'title': 'Water', 'description': 'participants ingested 500 mL of deionized water twice daily, with breakfast and dinner.'}], 'classes': [{'categories': [{'measurements': [{'value': '6.0', 'spread': '0.6', 'groupId': 'OG000'}, {'value': '6.0', 'spread': '0.5', 'groupId': 'OG001'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'at the end of each 6-day intervention in Cola and Water Phase', 'description': 'The Urine pH that were assessed at the end of cola and water (arms) phase The parameters were consolidated into the one value as a mean of all the values in the phase or group (Table 3) and later for longitudinal analysis as a mean of all the values in the phase for each participant (Table 4).\n\nmeasure of dispersion was standard deviation.', 'unitOfMeasure': 'pH', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED'}, {'type': 'PRIMARY', 'title': 'The Plasma and Urine Parameters', 'denoms': [{'units': 'Participants', 'counts': [{'value': '13', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Water', 'description': 'participants ingested 500 mL of deionized water twice daily, with breakfast and dinner.'}, {'id': 'OG001', 'title': 'Cola', 'description': 'they ingested 500 mL of cola (regular Publix brand©) twice daily, with breakfast and dinner.'}], 'classes': [{'title': 'Urinary sodium', 'categories': [{'measurements': [{'value': '139.9', 'spread': '40.0', 'groupId': 'OG000'}, {'value': '103.9', 'spread': '43.5', 'groupId': 'OG001'}]}]}, {'title': 'Urinary Potassium', 'categories': [{'measurements': [{'value': '49.3', 'spread': '31.4', 'groupId': 'OG000'}, {'value': '41.4', 'spread': '17.1', 'groupId': 'OG001'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'at the end of 6-day intervention of Cola and water phase', 'description': 'The Urine Parameters that were assessed at the end of cola and water (arms) phase:\n\nUrine Parameters:\n\nuNa (mEq per d) uK (mEq per d)\n\nThe parameters were consolidated into the one value as a mean of all the values in the phase or group (Table 3) and later for longitudinal analysis as a mean of all the values in the phase for each participant (Table 4).\n\nmeasure of dispersion was standard deviation.', 'unitOfMeasure': 'mEq per d', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED'}]}, 'participantFlowModule': {'groups': [{'id': 'FG000', 'title': 'Cola First, Then Water', 'description': 'Phase 1: Subjects will be given 500cc of Cola beverage twice daily to be ingested with breakfast and dinner for six days while on a metabolic diet.\n\nThere will be a three weeks wash-out period before patients entere phase 2 of thre study.\n\nPhase 2: Subjects will be given 500cc of deionized water twice daily to be ingested with breakfast and dinner for six days while on a metabolic diet.'}], 'periods': [{'title': 'Overall Study', 'milestones': [{'type': 'STARTED', 'achievements': [{'groupId': 'FG000', 'numSubjects': '13'}]}, {'type': 'COMPLETED', 'achievements': [{'groupId': 'FG000', 'numSubjects': '13'}]}, {'type': 'NOT COMPLETED', 'achievements': [{'groupId': 'FG000', 'numSubjects': '0'}]}]}], 'recruitmentDetails': 'Recruited patients of Emory University Department of Urology', 'preAssignmentDetails': 'Normal subjects and calcium oxalate stone-formers were included.'}, 'baselineCharacteristicsModule': {'denoms': [{'units': 'Participants', 'counts': [{'value': '13', 'groupId': 'BG000'}]}], 'groups': [{'id': 'BG000', 'title': 'Cola First, Then Water', 'description': 'Phase 1: Subjects will be given 500cc of Cola beverage twice daily to be ingested with breakfast and dinner for six days while on a metabolic diet.\n\nThere will be a 3-week wash out period before subjects enter phase 2 of the study.\n\nPhase 2: Subjects will be given 500 cc of deionized water beverage twice daily to be ingested with breakfast and dinner for six days while on a metabolic diet.'}], 'measures': [{'title': 'Age, Categorical', 'classes': [{'categories': [{'title': '<=18 years', 'measurements': [{'value': '0', 'groupId': 'BG000'}]}, {'title': 'Between 18 and 65 years', 'measurements': [{'value': '13', 'groupId': 'BG000'}]}, {'title': '>=65 years', 'measurements': [{'value': '0', 'groupId': 'BG000'}]}]}], 'paramType': 'COUNT_OF_PARTICIPANTS', 'unitOfMeasure': 'Participants'}, {'title': 'Sex: Female, Male', 'classes': [{'categories': [{'title': 'Female', 'measurements': [{'value': '4', 'groupId': 'BG000'}]}, {'title': 'Male', 'measurements': [{'value': '9', 'groupId': 'BG000'}]}]}], 'paramType': 'COUNT_OF_PARTICIPANTS', 'unitOfMeasure': 'Participants'}, {'title': 'Study participants', 'classes': [{'title': 'Normal subjects', 'categories': [{'measurements': [{'value': '10', 'groupId': 'BG000'}]}]}, {'title': 'Calcium oxalate stone- formers', 'categories': [{'measurements': [{'value': '3', 'groupId': 'BG000'}]}]}], 'paramType': 'NUMBER', 'unitOfMeasure': 'participants'}], 'populationDescription': 'Thirteen subjects, including 10 normal subjects and 3 calcium oxalate stone-formers were enrolled in this prospective cross-over study.'}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'NON_RANDOMIZED', 'maskingInfo': {'masking': 'NONE'}, 'primaryPurpose': 'HEALTH_SERVICES_RESEARCH', 'interventionModel': 'CROSSOVER'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 13}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2003-11'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2016-05', 'completionDateStruct': {'date': '2011-10', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2016-05-05', 'studyFirstSubmitDate': '2006-02-07', 'resultsFirstSubmitDate': '2013-08-14', 'studyFirstSubmitQcDate': '2006-02-07', 'lastUpdatePostDateStruct': {'date': '2016-06-08', 'type': 'ESTIMATED'}, 'resultsFirstSubmitQcDate': '2014-06-05', 'studyFirstPostDateStruct': {'date': '2006-02-09', 'type': 'ESTIMATED'}, 'resultsFirstPostDateStruct': {'date': '2014-07-08', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2011-10', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'The Plasma and Urine Parameters', 'timeFrame': 'at the end of each 6-day intervention in Cola and Water Phase', 'description': 'The Plasma and Urine Parameters that were assessed at the end of cola and water (arms) phase:\n\nPlasma Parameters:\n\nCA (mg per dL) GLU (mg per dL) BUN (mg per dL) Cr (mg per dL) Prot (mg per dL) ALB (mg per dL)\n\nUrine Parameters:\n\nuCa (mg per dL) uMg (mg per dL) uP (mg per dL) uCr (mg per dL) uCit (mg per dL) uOx (mg per dL) uUA (mg per dL)\n\nThe parameters were consolidated into the one value as a mean of all the values in the phase or group (Table 3) and later for longitudinal analysis as a mean of all the values in the phase for each participant (Table 4).\n\nmeasure of dispersion was standard deviation.'}, {'measure': 'The Plasma and Urine Parameters', 'timeFrame': 'at the end of 6-day intervention of Cola and water phase', 'description': 'The Plasma and Urine Parameters that were assessed at the end of cola and water (arms) phase:\n\nPlasma Parameters:\n\nNa (mEq per L) K (mEq per L) CL (mEq per L) CO2(mEq per L) AG (mEq per L)\n\nThe parameters were consolidated into the one value as a mean of all the values in the phase or group (Table 3) and later for longitudinal analysis as a mean of all the values in the phase for each participant (Table 4).\n\nmeasure of dispersion was standard deviation.'}, {'measure': 'The Plasma Osmolarity', 'timeFrame': 'at the end of 6-day intervention of cola and water phase', 'description': 'The Plasma osmolarity that were assessed at the end of cola and water (arms) phase:\n\nPlasma Parameters:\n\nOSM (mOsm/L)\n\nThe parameters were consolidated into the one value as a mean of all the values in the phase or group (Table 3) and later for longitudinal analysis as a mean of all the values in the phase for each participant (Table 4).\n\nmeasure of dispersion was standard deviation.'}, {'measure': 'The Plasma and Urine Parameters', 'timeFrame': 'at the end of 6-day intervention of Cola and water phase', 'description': 'The Urine Parameters that were assessed at the end of cola and water (arms) phase:\n\nUrine Parameters:\n\nuNa (mEq per d) uK (mEq per d)\n\nThe parameters were consolidated into the one value as a mean of all the values in the phase or group (Table 3) and later for longitudinal analysis as a mean of all the values in the phase for each participant (Table 4).\n\nmeasure of dispersion was standard deviation.'}], 'secondaryOutcomes': [{'measure': 'Total Urine Volume', 'timeFrame': 'at the end of each 6-day intervention in Cola and Water Phase', 'description': 'The Plasma and Urine Parameters that were assessed at the end of cola and water (arms) phase:\n\nUrine Parameters:\n\nTotal Urine Volume (mL/day)\n\nThe parameters were consolidated into the one value as a mean of all the values in the phase or group (Table 3) and later for longitudinal analysis as a mean of all the values in the phase for each participant (Table 4).\n\nmeasure of dispersion was standard deviation.'}, {'measure': 'Urinary pH', 'timeFrame': 'at the end of each 6-day intervention in Cola and Water Phase', 'description': 'The Urine pH that were assessed at the end of cola and water (arms) phase The parameters were consolidated into the one value as a mean of all the values in the phase or group (Table 3) and later for longitudinal analysis as a mean of all the values in the phase for each participant (Table 4).\n\nmeasure of dispersion was standard deviation.'}]}, 'oversightModule': {'oversightHasDmc': False}, 'conditionsModule': {'keywords': ['urolithiasis, cola'], 'conditions': ['Kidney Stone']}, 'referencesModule': {'references': [{'pmid': '23017784', 'type': 'RESULT', 'citation': 'Herrel L, Pattaras J, Solomon T, Ogan K. Urinary stone risk and cola consumption. Urology. 2012 Nov;80(5):990-4. doi: 10.1016/j.urology.2012.07.003. Epub 2012 Sep 25.'}]}, 'descriptionModule': {'briefSummary': 'Examine the effects of cola on risks of kidney stones', 'detailedDescription': 'Prospective crossover study examining the risks of cola on stone risk factors.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* urolithiasis, healthy volunteer\n\nExclusion Criteria:\n\n\\-'}, 'identificationModule': {'nctId': 'NCT00289120', 'briefTitle': 'Effect of Cola on Urinary Stone Risk Factors', 'organization': {'class': 'OTHER', 'fullName': 'Emory University'}, 'officialTitle': 'Effect of Cola on Urinary Stone Risk Factors', 'orgStudyIdInfo': {'id': '0133-2003'}, 'secondaryIdInfos': [{'id': 'GCRC#2403'}]}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'Cola beverage', 'description': 'Subjects will be given 500cc of Cola twice daily.', 'interventionNames': ['Drug: Cola beverage']}, {'type': 'PLACEBO_COMPARATOR', 'label': 'Deionized water', 'description': 'Subjects will be given 500cc of deionized water.', 'interventionNames': ['Drug: Deionized water']}], 'interventions': [{'name': 'Cola beverage', 'type': 'DRUG', 'description': 'Subjects will be given 500cc of Cola beverage twice daily to be ingested with breakfast and dinner for six days while on a metabolic diet.There will be a three weeks interval before crossover to the other treatment arm.', 'armGroupLabels': ['Cola beverage']}, {'name': 'Deionized water', 'type': 'DRUG', 'description': 'Subjects will be given 500cc of deionized water to be ingested twice daily with breakfast and dinner for three weeks while on a metabolic diet. There will be a three weeks interval before crossover to the other treatment arm', 'armGroupLabels': ['Deionized water']}]}, 'contactsLocationsModule': {'locations': [{'zip': '30322', 'city': 'Atlanta', 'state': 'Georgia', 'country': 'United States', 'facility': 'Emory University', 'geoPoint': {'lat': 33.749, 'lon': -84.38798}}], 'overallOfficials': [{'name': 'Kenneth Ogan, MD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Emory University'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Emory University', 'class': 'OTHER'}, 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Associate Professor', 'investigatorFullName': 'Kenneth Ogan, MD', 'investigatorAffiliation': 'Emory University'}}}}