Ignite Creation Date:
2025-12-24 @ 2:58 PM
Ignite Modification Date:
2026-01-22 @ 1:02 AM
Study NCT ID:
NCT06808659
Status:
COMPLETED
Last Update Posted:
2025-02-05
First Post:
2024-11-29
Is Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Effects of Neural Mobilization and Stretching in Piriformis Syndrome
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D055958', 'term': 'Piriformis Muscle Syndrome'}, {'id': 'D000377', 'term': 'Agnosia'}], 'ancestors': [{'id': 'D020426', 'term': 'Sciatic Neuropathy'}, {'id': 'D020422', 'term': 'Mononeuropathies'}, {'id': 'D010523', 'term': 'Peripheral Nervous System Diseases'}, {'id': 'D009468', 'term': 'Neuromuscular Diseases'}, {'id': 'D009422', 'term': 'Nervous System Diseases'}, {'id': 'D009408', 'term': 'Nerve Compression Syndromes'}, {'id': 'D009437', 'term': 'Neuralgia'}, {'id': 'D010146', 'term': 'Pain'}, {'id': 'D009461', 'term': 'Neurologic Manifestations'}, {'id': 'D012816', 'term': 'Signs and Symptoms'}, {'id': 'D013568', 'term': 'Pathological Conditions, Signs and Symptoms'}, {'id': 'D017699', 'term': 'Pelvic Pain'}, {'id': 'D010468', 'term': 'Perceptual Disorders'}, {'id': 'D019954', 'term': 'Neurobehavioral Manifestations'}]}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'NONE'}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'PARALLEL', 'interventionModelDescription': 'In a study involving 40 patients diagnosed with sciatica, researchers aimed to investigate whether neural mobilization of the sciatic nerve or stretching of the piriformis muscle was more effective in treating piriformis syndrome. The patients were divided into two groups, each containing 20 individuals. Group A underwent neural mobilization therapy, while Group B performed piriformis muscle stretches, with both groups receiving treatment three times a week for two weeks. Assessments, including Visual Analog Scale (VAS) for pain, hip range of motion (ROM) in flexion, abduction, and external rotation, as well as the FAIR test, were conducted before and after the interventions.'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 40}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2018-05-02', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2025-01', 'completionDateStruct': {'date': '2018-12-28', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2025-01-29', 'studyFirstSubmitDate': '2024-11-29', 'studyFirstSubmitQcDate': '2025-01-29', 'lastUpdatePostDateStruct': {'date': '2025-02-05', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2025-02-05', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2018-11-10', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Pain Reduction', 'timeFrame': '2 weeks', 'description': 'Two different interventions were applied in groups after which pain was recorded before and after through visual analogue scale. Highest score means high level of pain and lower score refers to low pain. Maximum score 9 was reported pre study and minmum score 2 was reported after study by both groups on average.'}, {'measure': 'Increase Range of Motion', 'timeFrame': '2 weeks', 'description': 'Through neural mobilization and piriformis stretching renage of motion was assessed through inclino meter before and after study'}]}, 'oversightModule': {'oversightHasDmc': False, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'keywords': ['Physiotherapy', 'Piriformis Stretching', 'Visual Analog Scale (VAS)', 'Pain Management', 'FAIR Test', 'Range of Motion'], 'conditions': ['Piriformis Syndrome']}, 'referencesModule': {'references': [{'pmid': '37240853', 'type': 'BACKGROUND', 'citation': 'Othman IK, Raj NB, Siew Kuan C, Sidek S, Wong LS, Djearamane S, Loganathan A, Selvaraj S. Association of Piriformis Thickness, Hip Muscle Strength, and Low Back Pain Patients with and without Piriformis Syndrome in Malaysia. Life (Basel). 2023 May 18;13(5):1208. doi: 10.3390/life13051208.'}, {'pmid': '34099604', 'type': 'BACKGROUND', 'citation': 'Hu YE, Ho GWK, Tortland PD. Deep Gluteal Syndrome: A Pain in the Buttock. Curr Sports Med Rep. 2021 Jun 1;20(6):279-285. doi: 10.1249/JSR.0000000000000848.'}, {'pmid': '34049428', 'type': 'BACKGROUND', 'citation': 'Danazumi MS, Yakasai AM, Ibrahim AA, Shehu UT, Ibrahim SU. Effect of integrated neuromuscular inhibition technique compared with positional release technique in the management of piriformis syndrome. J Osteopath Med. 2021 May 31;121(8):693-703. doi: 10.1515/jom-2020-0327.'}, {'pmid': '29727344', 'type': 'BACKGROUND', 'citation': 'Burke CJ, Walter WR, Adler RS. Targeted Ultrasound-Guided Perineural Hydrodissection of the Sciatic Nerve for the Treatment of Piriformis Syndrome. Ultrasound Q. 2019 Jun;35(2):125-129. doi: 10.1097/RUQ.0000000000000360.'}, {'pmid': '32894238', 'type': 'BACKGROUND', 'citation': 'Shahzad M, Rafique N, Shakil-Ur-Rehman S, Ali Hussain S. Effects of ELDOA and post-facilitation stretching technique on pain and functional performance in patients with piriformis syndrome: A randomized controlled trial. J Back Musculoskelet Rehabil. 2020;33(6):983-988. doi: 10.3233/BMR-181290.'}, {'pmid': '36712711', 'type': 'BACKGROUND', 'citation': 'Ahmad Siraj S, Dadgal R. Physiotherapy for Piriformis Syndrome Using Sciatic Nerve Mobilization and Piriformis Release. Cureus. 2022 Dec 26;14(12):e32952. doi: 10.7759/cureus.32952. eCollection 2022 Dec.'}, {'pmid': '38410291', 'type': 'RESULT', 'citation': 'Ankar P, Ratnani GR, Ramteke SU, Jaiswal PR. Effect of Neuromuscular Training and Neurodynamic Solutions for Asymptomatic Prolapsed Intervertebral Disc and Coexisting Piriformis Syndrome in a 19-Year-Old: A Comprehensive Case Report. Cureus. 2024 Jan 27;16(1):e53050. doi: 10.7759/cureus.53050. eCollection 2024 Jan.'}], 'seeAlsoLinks': [{'url': 'https://pubmed.ncbi.nlm.nih.gov/?term=effect%20of%20piriformis%20syndrome%20on%20pain%20&filter=dates.2018%2F4%2F10-2023%2F12%2F30&page=3', 'label': 'Related Info'}]}, 'descriptionModule': {'briefSummary': 'This study compares the effects of piriformis stretching and neural mobilization of the sciatic nerve in individuals with piriformis syndrome, a condition that is frequently characterized by hip and buttock pain and discomfort brought on by the piriformis muscle compressing the sciatic nerve.', 'detailedDescription': 'In a study involving 40 patients diagnosed with sciatica, researchers aimed to investigate whether neural mobilization of the sciatic nerve or stretching of the piriformis muscle was more effective in treating piriformis syndrome. The patients were divided into two groups, each containing 20 individuals. Group A underwent neural mobilization therapy, while Group B performed piriformis muscle stretches, with both groups receiving treatment three times a week for two weeks. Assessments, including Visual Analog Scale (VAS) for pain, hip range of motion (ROM) in flexion, abduction, and external rotation, as well as the FAIR test, were conducted before and after the interventions.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'maximumAge': '65 Years', 'minimumAge': '22 Years', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Positive lasegue sign\n* Positive piriformis sign\n* Tenderness at sciatic notch (over piriformis muscle).\n\nExclusion Criteria:\n\n* • Prior surgery of lumbar spine (laminectomy)\n\n * Unrecognized pelvic fracture\n * Known case of renal stones\n * Disc herniation in lumbar spine\n * Myositis ossificans of piriformis muscle.'}, 'identificationModule': {'nctId': 'NCT06808659', 'briefTitle': 'Effects of Neural Mobilization and Stretching in Piriformis Syndrome', 'organization': {'class': 'OTHER', 'fullName': 'Bahria University'}, 'officialTitle': 'Comparative Effects of Neural Mobilization of Sciatic Nerve Versus Stretching Among Patients With Piriformis Syndrome', 'orgStudyIdInfo': {'id': 'IERC/IIRS-IU-KC/18/005'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'Group A / Sciatic Nerve Mobilization', 'description': 'Sciatic Nerve Mobilization was given to group A participants.', 'interventionNames': ['Other: Neural Mobilization']}, {'type': 'EXPERIMENTAL', 'label': 'Group B / Piriformis Muscle Stretching', 'description': 'Piriformis Muscles was stretched in group B participants.', 'interventionNames': ['Other: Stretching']}], 'interventions': [{'name': 'Neural Mobilization', 'type': 'OTHER', 'otherNames': ['Sciatic Nerve Mobilization'], 'description': 'A total of 20 patients were selected in Group A received neural mobilization of sciatic nerves treatment for 3 days a week for 2 weeks', 'armGroupLabels': ['Group A / Sciatic Nerve Mobilization']}, {'name': 'Stretching', 'type': 'OTHER', 'otherNames': ['Piriformis Stretching'], 'description': 'A total of 20 patients were selected in Group B received stretching of piriformis muscle treatment for 3 days a week for 2 weeks', 'armGroupLabels': ['Group B / Piriformis Muscle Stretching']}]}, 'contactsLocationsModule': {'locations': [{'zip': '74700', 'city': 'Karachi', 'state': 'Sindh', 'country': 'Pakistan', 'facility': 'Isra Institute of Rehabilitation Sciences', 'geoPoint': {'lat': 24.8608, 'lon': 67.0104}}], 'overallOfficials': [{'name': 'Rabia Khan, Masters of Science', 'role': 'PRINCIPAL_INVESTIGATOR'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'NO', 'description': 'Confidentiality'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Bahria University', 'class': 'OTHER'}, 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Assistant Professor', 'investigatorFullName': 'Rabia Khan', 'investigatorAffiliation': 'Bahria University'}}}}