Ignite Creation Date:
2025-12-24 @ 5:09 PM
Ignite Modification Date:
2025-12-24 @ 5:09 PM
Study NCT ID:
NCT03981250
Status:
SUSPENDED
Last Update Posted:
2020-09-30
First Post:
2019-06-06
Is Possible Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Effect of One Minute of Resistance Exercise Per Day on Muscular Strength (The ONE Study)
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D009043', 'term': 'Motor Activity'}], 'ancestors': [{'id': 'D001519', 'term': 'Behavior'}]}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'NONE', 'maskingDescription': 'There is no masking due to intervention characteristics (exercise training programme).'}, 'primaryPurpose': 'PREVENTION', 'interventionModel': 'PARALLEL', 'interventionModelDescription': 'Randomized controlled trial.'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 56}}, 'statusModule': {'whyStopped': 'Covid-19', 'overallStatus': 'SUSPENDED', 'startDateStruct': {'date': '2019-06-20', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2020-09', 'completionDateStruct': {'date': '2021-12-31', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2020-09-28', 'studyFirstSubmitDate': '2019-06-06', 'studyFirstSubmitQcDate': '2019-06-07', 'lastUpdatePostDateStruct': {'date': '2020-09-30', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2019-06-10', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2021-10-28', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Muscle strength', 'timeFrame': 'Change between baseline and 4 weeks', 'description': 'Change in 1-RM (one repetition maximum) (kg) for bench press, leg press and lat pull down (kg).'}, {'measure': 'Muscle strength', 'timeFrame': 'Change between baseline and 8 weeks', 'description': 'Change in 1-RM (one repetition maximum) (kg) for bench press, leg press and lat pull down (kg).'}, {'measure': 'Muscle strength', 'timeFrame': 'Change between baseline and 12 weeks', 'description': 'Change in 1-RM (one repetition maximum) (kg) for bench press, leg press and lat pull down (kg).'}], 'secondaryOutcomes': [{'measure': 'Muscle endurance', 'timeFrame': 'Change between baseline and 4 weeks', 'description': 'Change in maximal number of repetitions with a load of 50% of baseline 1-RM for bench press, leg press and lateral pull down.'}, {'measure': 'Muscle endurance', 'timeFrame': 'Change between baseline and 8 weeks', 'description': 'Change in maximal number of repetitions with a load of 50% of baseline 1-RM for bench press, leg press and lateral pull down.'}, {'measure': 'Muscle endurance', 'timeFrame': 'Change between baseline and 12 weeks', 'description': 'Change in maximal number of repetitions with a load of 50% of baseline 1-RM for bench press, leg press and lateral pull down.'}, {'measure': 'Weight', 'timeFrame': 'Change between baseline and 4 weeks', 'description': 'Change in weight (kg).'}, {'measure': 'Weight', 'timeFrame': 'Change between baseline and 8 weeks', 'description': 'Change in weight (kg).'}, {'measure': 'Weight', 'timeFrame': 'Change between baseline and 12 weeks', 'description': 'Change in weight (kg).'}, {'measure': 'Waist', 'timeFrame': 'Change between baseline and 4 weeks', 'description': 'Change in waist circumference (cm).'}, {'measure': 'Waist', 'timeFrame': 'Change between baseline and 8 weeks', 'description': 'Change in waist circumference (cm).'}, {'measure': 'Waist', 'timeFrame': 'Change between baseline and 12 weeks', 'description': 'Change in waist circumference (cm).'}, {'measure': 'Body composition', 'timeFrame': 'Change between baseline and 4 weeks', 'description': 'Change in fat mass and free fat mass measured by Bioelectrical Impedance Analysis (BIA).'}, {'measure': 'Body composition', 'timeFrame': 'Change between baseline and 8 weeks', 'description': 'Change in fat mass and free fat mass measured by Bioelectrical Impedance Analysis (BIA).'}, {'measure': 'Body composition', 'timeFrame': 'Change between baseline and 12 weeks', 'description': 'Change in fat mass and free fat mass measured by Bioelectrical Impedance Analysis (BIA).'}, {'measure': 'Muscle thickness', 'timeFrame': 'Change between baseline and 12 weeks', 'description': 'Change in muscle thickness of vastus lateralis (mm) measured with ultrasound.'}, {'measure': 'Grip strength', 'timeFrame': 'Change between baseline and 4 weeks', 'description': 'Change in grip strength (kg) measured using a hand grip dynamometer'}, {'measure': 'Grip strength', 'timeFrame': 'Change between baseline and 8 weeks', 'description': 'Change in grip strength (kg) measured using a hand grip dynamometer'}, {'measure': 'Grip strength', 'timeFrame': 'Change between baseline and 12 weeks', 'description': 'Change in grip strength (kg) measured using a hand grip dynamometer'}]}, 'oversightModule': {'oversightHasDmc': False, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'keywords': ['Resistance training', 'Strength Training', 'Muscle Strength', 'voluntary failure'], 'conditions': ['Exercise']}, 'descriptionModule': {'briefSummary': 'This study will evaluate the effect of one minute of resistance exercise per day on muscular strength in adults. Half of the participants will undergo a 12-week home-based resistance exercise programme, while the other half will continue their usual lifestyle behaviour.', 'detailedDescription': 'A resistance training programme can lead to a variety of health benefits including increases in muscle size and strength. Other potential health benefits of resistance training include reduction of body fat, increased metabolic rate, improve insulin sensitivity, blood glucose tolerance and blood lipid profiles. Meta-analyses indicate that while performing resistance exercise two or more times per week of resistance exercise per muscle group appears to be optimal to maximise strength gains, a single set of resistance exercise per muscle group per week, if performed to failure is sufficient to induce substantial strength changes.\n\nThe current physical activity guidelines recommend undertaking muscle strengthening activities involving major muscle groups two days a week or more, as well as undertaking at least 150 minutes per week of moderate intensity physical activity (or 75 minutes per week of vigorous intensity physical activity). However, only small portion of the population achieves the muscle strengthening aspect of the guidelines. As lack of time is often cited as a reason not to engage in physical activity, this study is seeking to investigate a low time-commitment approach to resistance exercise which could increase muscular strength. To address this, the present study will to split a typical single session of resistance exercise involving several exercises across different muscle groups into separate 1-minute micro-sessions where a different muscle group is exercised on each day of the week. The aim is to determine the effects of a one-minute-per-day home-based resistance exercise training on muscular strength.\n\nThe study is a randomized control trial in which the control group will continue their lifestyle behaviour and will be asked not to increase their physical activity levels and the exercise group will perform a 12-week home-based resistance exercise programme, involving doing one minute of resistance exercise per day on six days of the week, with a different exercise performed on each day. All participants will be measured at baseline, 4 weeks, 8 weeks and 12 weeks.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'maximumAge': '65 Years', 'minimumAge': '18 Years', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Aged 18-65 years\n\nExclusion Criteria:\n\n* Diabetes\n* Uncontrolled hypertension (blood pressure \\> 150/90 on medication).\n* History of cardiovascular disease\n* Undertaking more than 150 minutes of moderate intensity or 75 minutes of vigorous physical activity or undertaking any resistance exercise.\n* Other significant illness that would prevent the participant to undertake physical activity.'}, 'identificationModule': {'nctId': 'NCT03981250', 'briefTitle': 'Effect of One Minute of Resistance Exercise Per Day on Muscular Strength (The ONE Study)', 'organization': {'class': 'OTHER', 'fullName': 'University of Glasgow'}, 'officialTitle': 'The ONE Study: Effect of One Minute of Resistance Exercise Per Day on Muscular Strength', 'orgStudyIdInfo': {'id': '200180137'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'NO_INTERVENTION', 'label': 'Control Group', 'description': 'The control group will be asked to keep their lifestyle behaviour and not increase their physical activity levels during the study period.'}, {'type': 'EXPERIMENTAL', 'label': 'Exercise Group', 'description': 'The exercise group will engage in a home-based resistance exercise intervention for 12 weeks. They will perform 6 exercises, one each day for one minute, for 6 days a week.', 'interventionNames': ['Behavioral: 12-week home-based resistance exercise programme']}], 'interventions': [{'name': '12-week home-based resistance exercise programme', 'type': 'BEHAVIORAL', 'description': 'Participants will perform 6 exercises (press-ups, squats, squat jumps, plank, upright row and seated row) for one minute, aiming for the maximum number of repetitions. Participants will perform one exercise per day, for 6 days a week, for 12 weeks.', 'armGroupLabels': ['Exercise Group']}]}, 'contactsLocationsModule': {'locations': [{'zip': 'G12 8TA', 'city': 'Glasgow', 'country': 'United Kingdom', 'facility': 'University of Glasgow', 'geoPoint': {'lat': 55.86515, 'lon': -4.25763}}], 'overallOfficials': [{'name': 'Jason Gill, PhD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'University of Glasgow'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'NO'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'University of Glasgow', 'class': 'OTHER'}, 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Professor', 'investigatorFullName': 'Professor Jason Gill', 'investigatorAffiliation': 'University of Glasgow'}}}}