Ignite Creation Date:
2025-12-24 @ 5:54 PM
Ignite Modification Date:
2025-12-31 @ 1:41 AM
Study NCT ID:
NCT07298668
Status:
NOT_YET_RECRUITING
Last Update Posted:
2025-12-23
First Post:
2025-11-26
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Cardiovascular Risk Factors in Middle Eastern Patients With Stroke
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D020521', 'term': 'Stroke'}], 'ancestors': [{'id': 'D002561', 'term': 'Cerebrovascular Disorders'}, {'id': 'D001927', 'term': 'Brain Diseases'}, {'id': 'D002493', 'term': 'Central Nervous System Diseases'}, {'id': 'D009422', 'term': 'Nervous System Diseases'}, {'id': 'D014652', 'term': 'Vascular Diseases'}, {'id': 'D002318', 'term': 'Cardiovascular Diseases'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'RETROSPECTIVE', 'observationalModel': 'CASE_ONLY'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 2000}, 'patientRegistry': False}, 'statusModule': {'overallStatus': 'NOT_YET_RECRUITING', 'startDateStruct': {'date': '2025-12-31', 'type': 'ESTIMATED'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2025-12', 'completionDateStruct': {'date': '2027-01-31', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2025-12-22', 'studyFirstSubmitDate': '2025-11-26', 'studyFirstSubmitQcDate': '2025-12-22', 'lastUpdatePostDateStruct': {'date': '2025-12-23', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2025-12-23', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2026-12-31', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Prevalence of hypertension in stroke patients (survey interview)', 'timeFrame': 'Baseline', 'description': 'BP more 140/90 or known diagnosis of high blood pressure or patient already on blood pressure medication'}, {'measure': 'Prevalence of type 2 diabetes in stroke patients (survey interview)', 'timeFrame': 'BASELINE', 'description': 'HbA1c more than 6.5%, or known diagnosis of type 2 diabetes or patient already on anti diabetes medications'}, {'measure': 'Prevalence of elevated serum level of low density lipoprotein cholesterol in stroke patients (survey interview)', 'timeFrame': 'BASELINE', 'description': 'Elevated serum level of low density lipoprotein cholesterol \\> 55 mg/dl or patient already on lipid lowering medication'}, {'measure': 'Prevalence of current cigarette smoking in stroke patients (survey interview)', 'timeFrame': 'BASELINE', 'description': 'Known current cigarette smoking of any number of cigarettes per day'}, {'measure': 'Use of lipid lowering therapy (survey interview)', 'timeFrame': 'BASELINE', 'description': 'Current use of statin, ezitimibe, PCS9 inhibitor of small interfering RNA agent to lower the LDL-C'}]}, 'oversightModule': {'oversightHasDmc': True, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'keywords': ['Stroke', 'Risk factors'], 'conditions': ['Stroke', 'Low-Density-Lipoprotein-cholesterol Level', 'Risk Factors']}, 'descriptionModule': {'briefSummary': 'Stroke is a well-known a leading cause of death and disability in the Middle East. There remain many knowledge gaps in evaluating the prevalence of risk factors among patients with stroke in the Middle East. Unravelling the impact of these risk factors and controlling them can positively lower the incidence of stroke. Disparities in stroke risk factors, may well be related to ethnicity of the Middle Eastern populations , will be compared with those among stroke patients in the western literature.', 'detailedDescription': 'Stroke is a well-known a leading cause of death and disability in the Middle East. There remain many knowledge gaps in evaluating the prevalence of risk factors among patients with stroke in the Middle East. Unravelling the impact of these risk factors and controlling them can positively lower the incidence of stroke. Disparities in stroke risk factors, may well be related to ethnicity of the Middle Eastern populations , will be compared with those among stroke patients in the western literature.\n\nThese clinically relevant issues have not been studied extensively in the Middle East where most of the studies in atherosclerotic cardiovascular disease have focused on acute coronary syndrome more than stroke. Exploring new information on risk factors of stroke in this region that helps fill some of the knowledge gaps.\n\nStroke has been attributed, in the majority of cases, to the traditional four standard modifiable risk factors of hypertension, type 2 diabetes, dyslipidemia, and cigarette smoking. However, ethnicity and geography account for the interregional differences of the prevalence of risk factors in patients with stroke.\n\nThe Jo-SMMART ill evaluate risk factors in 2000 stroke patients in Jordan as a representative of the Middle Eastern population, the prevalence of those with none of the 4 risk factors and the differences in clinical profiles and demographic features on those with risk factors and those with no risk factors. Lipid profile and use of lipid lowering agents will also be evaluated, and furthermore the die0fferneces between young vs old, and men vs women stroke patients ill be addressed.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'samplingMethod': 'NON_PROBABILITY_SAMPLE', 'studyPopulation': 'Will enroll adults admitted to the hospital with a working diagnosis of stroke and then the diagnosis is confirmed by a neurologist. Patients ii be interviewed for data collection of 4 risk factors as above in addition to the serum level of LDLC and the use of lipid lowering agents.', 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Diagnosis of stroke upon admission to the hospital\n* Adult aged 18 years or older\n* Available lipid profile on hospital admission\n\nExclusion Criteria:\n\n* Stroke diagnosis unconfirmed\n* age younger than 18 years\n* No available lipid profile on admission'}, 'identificationModule': {'nctId': 'NCT07298668', 'acronym': 'JoSMMART', 'briefTitle': 'Cardiovascular Risk Factors in Middle Eastern Patients With Stroke', 'organization': {'class': 'OTHER', 'fullName': 'Jordan Collaborating Cardiology Group'}, 'officialTitle': 'Standard Modifiable Risk Factors in Middle Eastern Patients With Stroke (Jo-SMMART Study)', 'orgStudyIdInfo': {'id': 'JOCVA1.NOV2025/2'}}, 'contactsLocationsModule': {'locations': [{'zip': '11184', 'city': 'Amman', 'country': 'Jordan', 'contacts': [{'name': 'Laith Habahbeh, MD', 'role': 'CONTACT', 'email': 'hammoudeh_ayman@yahoo.com', 'phone': '065001000'}, {'name': 'Ayman Hammoudeh, MD, FACC, FSCAI', 'role': 'CONTACT', 'email': 'hammoudeh_ayman@yahoo.com', 'phone': '065001000'}], 'facility': 'Istishari Hospital', 'geoPoint': {'lat': 31.95522, 'lon': 35.94503}}], 'centralContacts': [{'name': 'Laith Habahbeh, MD', 'role': 'CONTACT', 'email': 'a.hammoudeh@istisharihospital.com', 'phone': '065001000'}, {'name': 'Ayman Hammoudeh, MD, FACC', 'role': 'CONTACT', 'email': 'hammoudeh_ayman@yahoo.com', 'phone': '065001000'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'YES', 'description': 'All individual participant data will be available in the form of excel sheet with no disclosure of patients names. Can be requested from the study director'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Jordan Collaborating Cardiology Group', 'class': 'OTHER'}, 'responsibleParty': {'type': 'SPONSOR'}}}}