Ignite Creation Date:
2025-12-24 @ 12:53 PM
Ignite Modification Date:
2026-01-24 @ 1:40 AM
Study NCT ID:
NCT06711861
Status:
RECRUITING
Last Update Posted:
2024-12-02
First Post:
2024-08-21
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Multicenter Retrospective Study on Streptobacillus Moniliformis Infections in France
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D011906', 'term': 'Rat-Bite Fever'}, {'id': 'D015047', 'term': 'Zoonoses'}], 'ancestors': [{'id': 'D016905', 'term': 'Gram-Negative Bacterial Infections'}, {'id': 'D001424', 'term': 'Bacterial Infections'}, {'id': 'D001423', 'term': 'Bacterial Infections and Mycoses'}, {'id': 'D007239', 'term': 'Infections'}, {'id': 'D000820', 'term': 'Animal Diseases'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'RETROSPECTIVE', 'observationalModel': 'CASE_ONLY'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 20}, 'patientRegistry': False}, 'statusModule': {'overallStatus': 'RECRUITING', 'startDateStruct': {'date': '2024-02-16', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2024-08', 'completionDateStruct': {'date': '2025-02-16', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2024-11-28', 'studyFirstSubmitDate': '2024-08-21', 'studyFirstSubmitQcDate': '2024-11-28', 'lastUpdatePostDateStruct': {'date': '2024-12-02', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2024-12-02', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2025-02-16', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Retrospective study of the effectiveness of antibiotic therapy initiated for the treatment of Streptobacillus moniliformis infection.', 'timeFrame': 'Negative blood culture 15 days after the start of antibiotic therapy.', 'description': 'Clinical cure 15 days after the start of antibiotic therapy. This cure is based on a negative blood culture (absence of germs) performed 15 days after the start of treatment.'}]}, 'oversightModule': {'oversightHasDmc': False, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'keywords': ['Streptobacillus moniliformis', 'Zoonosis', 'Rat bites', 'Zoonotic diseases'], 'conditions': ['Streptobacillus Moniliformis Infections']}, 'descriptionModule': {'briefSummary': 'French data on Streptobacillus moniliformis infections (zoonosis transmitted by rat bites) are rare and there are no case series in the literature to date. This is a pathology presenting atypical clinical manifestations for a bacterial infection and which therefore remains underdiagnosed. Streptobacillus moniliformis infections can be fatal without appropriate antibiotic treatment. This study could improve diagnosis, develop early treatment strategies and contribute to the overall understanding of zoonotic diseases'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['CHILD', 'ADULT', 'OLDER_ADULT'], 'minimumAge': '1 Year', 'samplingMethod': 'NON_PROBABILITY_SAMPLE', 'studyPopulation': 'Patient having Streptobacillus moniliformis infection between 01/01/2007 and 31/12/2023', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Minor patient aged 1 to 17 years\n* Adult patient ≥18 years\n* Proven Streptobacillus moniliformis infection between 01/01/2007 and 31/12/2023\n* Subject not objecting, after being informed, to the reuse of their data for the purposes of this research\n* Holders of parental authority not objecting, after being informed, to the reuse of their data for the purposes of this research their child for the purposes of this research\n\nExclusion Criteria:\n\n* Subject and/or holder of parental authority having expressed opposition to participating in the study'}, 'identificationModule': {'nctId': 'NCT06711861', 'acronym': 'Streptobacil', 'briefTitle': 'Multicenter Retrospective Study on Streptobacillus Moniliformis Infections in France', 'organization': {'class': 'OTHER', 'fullName': 'University Hospital, Strasbourg, France'}, 'officialTitle': 'Multicenter Retrospective Study on Streptobacillus Moniliformis Infections in France', 'orgStudyIdInfo': {'id': '9237'}}, 'contactsLocationsModule': {'locations': [{'zip': '67091', 'city': 'Strasbourg', 'status': 'RECRUITING', 'country': 'France', 'contacts': [{'name': 'François DANION, MD', 'role': 'CONTACT', 'email': 'francois.danion@chru-strasbourg.fr', 'phone': '33 3 69 55 15 88'}, {'name': 'François DANION, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}, {'name': 'Amandine ROBERT, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}, {'name': 'Frédéric SCHRAMM, MD', 'role': 'SUB_INVESTIGATOR'}, {'name': 'GUILLOUZOUIC GUILLOUZOUIC, PharmD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Service des Maladies Infectieuses et Tropicales - CHU de Strasbourg - France', 'geoPoint': {'lat': 48.58392, 'lon': 7.74553}}], 'centralContacts': [{'name': 'François DANION, MD', 'role': 'CONTACT', 'email': 'francois.danion@chru-strasbourg.fr', 'phone': '33 3 69 55 15 88'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'University Hospital, Strasbourg, France', 'class': 'OTHER'}, 'responsibleParty': {'type': 'SPONSOR'}}}}