Ignite Creation Date:
2025-12-24 @ 1:06 PM
Ignite Modification Date:
2026-01-18 @ 8:44 PM
Study NCT ID:
NCT02219061
Status:
UNKNOWN
Last Update Posted:
2014-09-18
First Post:
2014-08-13
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Early Waning of Maternal Measles and Meningitis C Antibodies
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D008457', 'term': 'Measles'}], 'ancestors': [{'id': 'D018185', 'term': 'Morbillivirus Infections'}, {'id': 'D018184', 'term': 'Paramyxoviridae Infections'}, {'id': 'D018701', 'term': 'Mononegavirales Infections'}, {'id': 'D012327', 'term': 'RNA Virus Infections'}, {'id': 'D014777', 'term': 'Virus Diseases'}, {'id': 'D007239', 'term': 'Infections'}]}}, 'protocolSection': {'designModule': {'bioSpec': {'retention': 'SAMPLES_WITHOUT_DNA', 'description': "Children's Serum will be collected for measles and meningitis C antibodies test by ELISA method."}, 'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'PROSPECTIVE'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 100}, 'patientRegistry': False}, 'statusModule': {'overallStatus': 'UNKNOWN', 'lastKnownStatus': 'RECRUITING', 'startDateStruct': {'date': '2014-05'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2014-08', 'completionDateStruct': {'date': '2014-12', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2014-09-16', 'studyFirstSubmitDate': '2014-08-13', 'studyFirstSubmitQcDate': '2014-08-14', 'lastUpdatePostDateStruct': {'date': '2014-09-18', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2014-08-18', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2014-10', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Geometric Mean Titer', 'timeFrame': 'Up to six months'}]}, 'oversightModule': {'oversightHasDmc': True}, 'conditionsModule': {'keywords': ['Measles', 'Meningitis C', 'waning', 'Geometric Mean Titer', 'China'], 'conditions': ['Measles']}, 'descriptionModule': {'briefSummary': 'Maternal antibodies (measles and meningitis C) may wane in the first six months after birth.\n\n* Geometric mean titers(GMTs) of measles and meningitis C.\n* Follow-up on 0 month, 3rd month,5th month and 7th month after birth.', 'detailedDescription': 'Measles and meningitis C are hot topics in China in recent years. Although China had set the goal of measles elimination, many measles cases were found to be those aged \\< 8 months and meningitis C is becoming public health issue since meningitis group A has been controlled at a very low level and little is known on C group. So the investigators designed the observation study on the two antibodies.\n\nMaternal antibodies are supposed to wane after birth. Serums of the placenta(0 month), children of 3 months, 5 months and 7 months old will be collected and the geometric mean titers (GMTs) of measles and meningitis C will be confirmed by using the ELISA test.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['CHILD'], 'maximumAge': '7 Months', 'samplingMethod': 'NON_PROBABILITY_SAMPLE', 'studyPopulation': 'Infants.', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Healthy infants.\n\nExclusion Criteria:\n\n* Infants with poor score.'}, 'identificationModule': {'nctId': 'NCT02219061', 'acronym': 'EWMM', 'briefTitle': 'Early Waning of Maternal Measles and Meningitis C Antibodies', 'organization': {'class': 'OTHER_GOV', 'fullName': 'Guangzhou Center for Disease Control and Prevention'}, 'officialTitle': 'Observation Study on Early Waning of Maternal Measles and Meningitis C Antibodies', 'orgStudyIdInfo': {'id': 'GZCDC001'}}, 'armsInterventionsModule': {'armGroups': [{'label': 'GMT'}]}, 'contactsLocationsModule': {'locations': [{'zip': '510440', 'city': 'Guangzhou', 'state': 'Guangdong', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Chuanxi', 'role': 'CONTACT', 'phone': '+86 20 36055887'}, {'name': 'Ming', 'role': 'CONTACT', 'email': '48280698@qq.com'}, {'name': 'Long Lu, MPH', 'role': 'SUB_INVESTIGATOR'}], 'facility': 'Guangzhou Center for Disease Control and Prevention', 'geoPoint': {'lat': 23.11667, 'lon': 113.25}}], 'centralContacts': [{'name': 'Chuanxi Fu, PhD', 'role': 'CONTACT', 'email': 'fuchuanxi@gmail.com', 'phone': '+86 20 36055887'}], 'overallOfficials': [{'name': 'Ming Wang', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Guangzhou CDC'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Guangzhou Center for Disease Control and Prevention', 'class': 'OTHER_GOV'}, 'responsibleParty': {'type': 'SPONSOR'}}}}