Ignite Creation Date:
2025-12-24 @ 10:08 PM
Ignite Modification Date:
2025-12-26 @ 5:49 PM
Study NCT ID:
NCT06431035
Status:
COMPLETED
Last Update Posted:
2024-07-24
First Post:
2024-04-08
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Caffeine & Bodybuilding Dehydration Ability
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'interventionBrowseModule': {'meshes': [{'id': 'D002110', 'term': 'Caffeine'}], 'ancestors': [{'id': 'D014970', 'term': 'Xanthines'}, {'id': 'D000470', 'term': 'Alkaloids'}, {'id': 'D006571', 'term': 'Heterocyclic Compounds'}, {'id': 'D011688', 'term': 'Purinones'}, {'id': 'D011687', 'term': 'Purines'}, {'id': 'D006574', 'term': 'Heterocyclic Compounds, 2-Ring'}, {'id': 'D000072471', 'term': 'Heterocyclic Compounds, Fused-Ring'}]}}, 'documentSection': {'largeDocumentModule': {'largeDocs': [{'date': '2024-05-23', 'size': 488910, 'label': 'Study Protocol', 'hasIcf': False, 'hasSap': False, 'filename': 'Prot_000.pdf', 'typeAbbrev': 'Prot', 'uploadDate': '2024-05-24T06:10', 'hasProtocol': True}]}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'SINGLE', 'whoMasked': ['INVESTIGATOR'], 'maskingDescription': 'Using placebo chewing gum'}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'CROSSOVER', 'interventionModelDescription': 'The participants were divided into caffeine gum trial (CAF) and placebo trial (PL) with a randomized, double-blind study design.'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 14}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2024-04-08', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2024-07', 'completionDateStruct': {'date': '2024-06-30', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2024-07-23', 'studyFirstSubmitDate': '2024-04-08', 'studyFirstSubmitQcDate': '2024-05-24', 'lastUpdatePostDateStruct': {'date': '2024-07-24', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2024-05-28', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2024-06-30', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'dehydration speed', 'timeFrame': '15 minutes after intervention', 'description': 'The participants start dehydration until dehydrated to 2% of their original body weight.'}], 'secondaryOutcomes': [{'measure': 'energy expenditure', 'timeFrame': '15 minutes after intervention', 'description': 'The energy expenditure during dehydration'}]}, 'oversightModule': {'oversightHasDmc': False, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'conditions': ['Caffeine', 'Placebo']}, 'referencesModule': {'references': [{'pmid': '40287780', 'type': 'DERIVED', 'citation': 'Liu HS, Okada T, Mitsuya H, Hsieh MH, Hou CW, Chang CC, Chiu CH. Effects of caffeinated chewing gum-induced sympathetic activation and diuretic effect on the rapid rate of weight loss in bodybuilders: a double-blind crossover study. BMC Sports Sci Med Rehabil. 2025 Apr 26;17(1):98. doi: 10.1186/s13102-025-01144-z.'}]}, 'descriptionModule': {'briefSummary': '15-20 trained bodybuilding athletes were divided into caffeine gum trial (CAF) and placebo trial (PL) with a randomized, double-blind study design. The participants chewing either caffeine Gum (CAF trial, containing 5 mg/kg of caffeine) or placebo gum (PL) for 10 minutes. After rested for 15 minutes, Participants used the bicycle to adjust the pedal resistance and speed according to their own feelings until they were dehydrated to 2% of their original body weight.', 'detailedDescription': 'The purpose of this study was to investigate the effect of caffeinated chewing gum on dehydration ability in bodybuilding athletes. Methods: 15-20 trained bodybuilding athletes were divided into caffeine gum trial (CAF) and placebo trial (PL) with a randomized, double-blind study design. The participants chewing either caffeine Gum (CAF trial, containing 5 mg/kg of caffeine) or placebo gum (PL) for 10 minutes. After rested for 15 minutes, Participants used the bicycle to adjust the pedal resistance and speed according to their own feelings until they were dehydrated to 2% of their original body weight. Record time from exercise to completion of dehydration, heart rate, HRV, energy expenditure, fat oxidation rate and carbohydrate oxidation rate.'}, 'eligibilityModule': {'sex': 'MALE', 'stdAges': ['ADULT'], 'maximumAge': '40 Years', 'minimumAge': '20 Years', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* having won the top 8 places in a national competition,\n* having no cardiovascular or joint diseases\n* being an adult male\n\nExclusion Criteria:\n\n* no top 8 finishes at national level\n* cardiovascular or joint disease, or any other condition that could be impaired by exercise\n* female and underage participants\n* previous caffeine allergy'}, 'identificationModule': {'nctId': 'NCT06431035', 'briefTitle': 'Caffeine & Bodybuilding Dehydration Ability', 'organization': {'class': 'OTHER', 'fullName': 'National Taiwan Sport University'}, 'officialTitle': 'Effect of Caffeinated Chewing Gum on Dehydration Ability in Bodybuilding Athletes: a Crossover Trial', 'orgStudyIdInfo': {'id': '113-3'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'caffeine gum', 'description': 'Chewing caffeine Gum (CAF trial, containing 5 mg/kg of caffeine) for 10 minutes before test.', 'interventionNames': ['Dietary Supplement: caffeine']}, {'type': 'PLACEBO_COMPARATOR', 'label': 'placebo', 'description': 'Chewing placebo gum (without caffeine) for 10 minutes before test.', 'interventionNames': ['Dietary Supplement: caffeine']}], 'interventions': [{'name': 'caffeine', 'type': 'DIETARY_SUPPLEMENT', 'otherNames': ['plocabo gum'], 'description': 'The participants chewed either caffeine gum (5 mg/kg for 10 minutes per chew) or a placebo (10 minutes per chew, using regular gum).', 'armGroupLabels': ['caffeine gum', 'placebo']}]}, 'contactsLocationsModule': {'locations': [{'zip': '404', 'city': 'Taichung', 'country': 'Taiwan', 'facility': 'National Taiwan University of Sport', 'geoPoint': {'lat': 24.1469, 'lon': 120.6839}}], 'overallOfficials': [{'name': 'ChihHui Chiu, PhD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'National Taiwan University of Sport'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'NO', 'description': 'Only participant number and experimental data are provided.'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Chih-Hui Chiu', 'class': 'OTHER'}, 'responsibleParty': {'type': 'SPONSOR_INVESTIGATOR', 'investigatorTitle': 'Professor', 'investigatorFullName': 'Chih-Hui Chiu', 'investigatorAffiliation': 'National Taiwan Sport University'}}}}