Ignite Creation Date:
2025-12-26 @ 12:19 PM
Ignite Modification Date:
2026-01-13 @ 11:04 PM
Study NCT ID:
NCT00664300
Status:
COMPLETED
Last Update Posted:
2011-01-19
First Post:
2008-04-21
Is Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Facial Expression Recognition of Emotion and Categorization of Emotional Words in Gilles de la Tourette's Syndrome
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D005879', 'term': 'Tourette Syndrome'}], 'ancestors': [{'id': 'D001480', 'term': 'Basal Ganglia Diseases'}, {'id': 'D001927', 'term': 'Brain Diseases'}, {'id': 'D002493', 'term': 'Central Nervous System Diseases'}, {'id': 'D009422', 'term': 'Nervous System Diseases'}, {'id': 'D013981', 'term': 'Tic Disorders'}, {'id': 'D009069', 'term': 'Movement Disorders'}, {'id': 'D020271', 'term': 'Heredodegenerative Disorders, Nervous System'}, {'id': 'D019636', 'term': 'Neurodegenerative Diseases'}, {'id': 'D030342', 'term': 'Genetic Diseases, Inborn'}, {'id': 'D009358', 'term': 'Congenital, Hereditary, and Neonatal Diseases and Abnormalities'}, {'id': 'D065886', 'term': 'Neurodevelopmental Disorders'}, {'id': 'D001523', 'term': 'Mental Disorders'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 60}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2007-08'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2011-01', 'completionDateStruct': {'date': '2009-10', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2011-01-18', 'studyFirstSubmitDate': '2008-04-21', 'studyFirstSubmitQcDate': '2008-04-21', 'lastUpdatePostDateStruct': {'date': '2011-01-19', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2008-04-22', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2008-10', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Facial expression recognition test', 'timeFrame': '% of exact responses'}], 'secondaryOutcomes': [{'measure': 'Lexical decision test', 'timeFrame': 'The time to respond'}]}, 'conditionsModule': {'keywords': ["Gilles de la Tourette's syndrome", 'Facial expression recognition of emotion', 'Frequency levels', 'Automatic and voluntary information treatment', "Patient with Gilles de la Tourette's syndrome"], 'conditions': ["Gilles de la Tourette's Syndrome"]}, 'descriptionModule': {'briefSummary': "Gilles de la Tourette's syndrome is a childhood onset inherited neuropsychiatric disorder characterised by the presence of both multiple motor tics and one or more vocal tics (noises), with psychiatric and/or behaviour disorders (such as obsessive compulsive behaviour…).\n\nThis disease is associated with an dopamine system imbalance which could be responsible of a specific trouble in the recognition in some facial expression. This has been already shown in Gilles de la Tourette patients with obsessive compulsive behaviour.\n\nWe hypothesise that patients with Gilles de la Tourette's syndrome present a dysfunction of voluntary and automatic treatment of emotional information.\n\nThe main purpose of this study is to show if patients with Gilles de la Tourette's syndrome present a lack of specific facial expression recognition of emotion and determinate more precisely if this alteration involves the cortical way (high frequency way) or the under cortical way (low frequency way).", 'detailedDescription': "20 patients with Gilles de la Tourette's syndrome compared to 20 healthy paired volunteers.\n\nStudy progress (patients):\n\nInclusion visit :\n\nPsychiatric evaluation Psychological evaluation\n\nOphthalmic visit\n\nProtocol :\n\nFacial expression recognition test Lexical decision test\n\nStudy progress (healthy volunteers):\n\nPsychiatric evaluation Ophthalmic visit Facial expression recognition test Lexical decision test"}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'samplingMethod': 'PROBABILITY_SAMPLE', 'studyPopulation': "30 patients with Gilles de la Tourette's Syndrome and 30 healthy paired volunteers (control group)", 'healthyVolunteers': True, 'eligibilityCriteria': "Inclusion Criteria:\n\n* Age : \\>18 years\n* Patient with a Gilles de la Tourette 's syndrome such as defined in the DSMIV\n* Stability of treatment \\>1 month\n* Mini Mental State \\> 26\n* Affiliation to social security\n* Agreement of patients\n\nExclusion Criteria:\n\n* Patients with cognitive disorders, dementia, mental retardation…\n* Patients with serious neurological pathologies\n* Patients with a vision contrast altered.\n* Patients who do not understand the words associated with an emotion\n* Pregnant women\n* Person who participate to an other study"}, 'identificationModule': {'nctId': 'NCT00664300', 'briefTitle': "Facial Expression Recognition of Emotion and Categorization of Emotional Words in Gilles de la Tourette's Syndrome", 'organization': {'class': 'OTHER', 'fullName': 'University Hospital, Clermont-Ferrand'}, 'officialTitle': "Facial Expression Recognition of Emotion and Categorization of Emotional Words in Gilles de la Tourette's Syndrome", 'orgStudyIdInfo': {'id': 'CHU-0032'}, 'secondaryIdInfos': [{'id': 'RBHP 2007 Jalenques'}]}, 'armsInterventionsModule': {'armGroups': [{'label': '2', 'description': "One group with Gilles de la Tourette's Syndrome One group with healthy paired volunteers", 'interventionNames': ['Behavioral: Facial expression recognition of emotion']}], 'interventions': [{'name': 'Facial expression recognition of emotion', 'type': 'BEHAVIORAL', 'description': 'Facial expression recognition test Lexical decision test', 'armGroupLabels': ['2']}]}, 'contactsLocationsModule': {'locations': [{'zip': '63003', 'city': 'Clermont-Ferrand', 'country': 'France', 'facility': 'CHU', 'geoPoint': {'lat': 45.77969, 'lon': 3.08682}}], 'overallOfficials': [{'name': 'Isabelle Jalenques, PUPH', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'University Hospital, Clermont-Ferrand'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'University Hospital, Clermont-Ferrand', 'class': 'OTHER'}, 'responsibleParty': {'oldNameTitle': 'Pr Jalenques', 'oldOrganization': 'CHU Clermont-Ferrand'}}}}