Ignite Creation Date:
2025-12-25 @ 12:39 AM
Ignite Modification Date:
2026-01-07 @ 7:05 AM
Study NCT ID:
NCT05183867
Status:
COMPLETED
Last Update Posted:
2025-09-09
First Post:
2021-12-21
Is NOT Gene Therapy:
True
Has Adverse Events:
True
Brief Title:
Behavior, Biology and Well-Being Study
Sponsor:
Organization:
Raw JSON
{'hasResults': True, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D003863', 'term': 'Depression'}], 'ancestors': [{'id': 'D001526', 'term': 'Behavioral Symptoms'}, {'id': 'D001519', 'term': 'Behavior'}]}}, 'resultsSection': {'moreInfoModule': {'pointOfContact': {'email': 'sbgoldberg@wisc.edu', 'phone': '(608) 265-8986', 'title': 'Simon Goldberg', 'organization': 'Center for Healthy Minds'}, 'certainAgreement': {'piSponsorEmployee': True}}, 'adverseEventsModule': {'timeFrame': 'data collected up to 4 months on study', 'eventGroups': [{'id': 'EG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive access to the 4-week HMP Foundations module. The HMP app is a meditation-based smartphone app designed to promote and protect psychological well-being through sustainable skills training. The program is grounded in constituents of psychological well-being identified in empirical literature. HMP provides core content, with instruction administered through a curriculum of guided practices. HMP is based on research on eudaimonic well-being (e.g., environmental mastery, purpose) and brain-based skills that underlie these qualities (e.g., regulation of attention, mental flexibility). The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.', 'otherNumAtRisk': 462, 'deathsNumAtRisk': 462, 'otherNumAffected': 78, 'seriousNumAtRisk': 462, 'deathsNumAffected': 0, 'seriousNumAffected': 0}, {'id': 'EG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.', 'otherNumAtRisk': 463, 'deathsNumAtRisk': 463, 'otherNumAffected': 64, 'seriousNumAtRisk': 463, 'deathsNumAffected': 0, 'seriousNumAffected': 0}, {'id': 'EG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.', 'otherNumAtRisk': 232, 'deathsNumAtRisk': 232, 'otherNumAffected': 44, 'seriousNumAtRisk': 232, 'deathsNumAffected': 0, 'seriousNumAffected': 0}], 'otherEvents': [{'term': 'Increased Symptoms of Depression', 'notes': 'Increase in scores PHQ-8 scores indicate increase is depression symptoms. This is the number of participants with increases of 5 points or more.', 'stats': [{'groupId': 'EG000', 'numAtRisk': 462, 'numAffected': 78}, {'groupId': 'EG001', 'numAtRisk': 463, 'numAffected': 64}, {'groupId': 'EG002', 'numAtRisk': 232, 'numAffected': 44}], 'organSystem': 'Psychiatric disorders', 'assessmentType': 'NON_SYSTEMATIC_ASSESSMENT'}], 'frequencyThreshold': '0'}, 'outcomeMeasuresModule': {'outcomeMeasures': [{'type': 'PRIMARY', 'title': 'Depression Symptoms Measured by Patient Health Questionnaire - 8 (PHQ-8) Score', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '10.06', 'spread': '4.85', 'groupId': 'OG000'}, {'value': '9.85', 'spread': '4.68', 'groupId': 'OG001'}, {'value': '9.79', 'spread': '4.75', 'groupId': 'OG002'}]}]}, {'title': 'Week 1', 'denoms': [{'units': 'Participants', 'counts': [{'value': '403', 'groupId': 'OG000'}, {'value': '407', 'groupId': 'OG001'}, {'value': '216', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '9.17', 'spread': '4.72', 'groupId': 'OG000'}, {'value': '8.8', 'spread': '4.71', 'groupId': 'OG001'}, {'value': '9.45', 'spread': '5.11', 'groupId': 'OG002'}]}]}, {'title': 'Week 2', 'denoms': [{'units': 'Participants', 'counts': [{'value': '376', 'groupId': 'OG000'}, {'value': '377', 'groupId': 'OG001'}, {'value': '204', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '8.37', 'spread': '4.75', 'groupId': 'OG000'}, {'value': '8.28', 'spread': '4.6', 'groupId': 'OG001'}, {'value': '9.03', 'spread': '5.22', 'groupId': 'OG002'}]}]}, {'title': 'Week 3', 'denoms': [{'units': 'Participants', 'counts': [{'value': '372', 'groupId': 'OG000'}, {'value': '366', 'groupId': 'OG001'}, {'value': '204', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '7.88', 'spread': '4.9', 'groupId': 'OG000'}, {'value': '8.01', 'spread': '4.84', 'groupId': 'OG001'}, {'value': '9.21', 'spread': '4.93', 'groupId': 'OG002'}]}]}, {'title': 'Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '395', 'groupId': 'OG000'}, {'value': '389', 'groupId': 'OG001'}, {'value': '218', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '7.21', 'spread': '4.8', 'groupId': 'OG000'}, {'value': '7.39', 'spread': '4.8', 'groupId': 'OG001'}, {'value': '8.86', 'spread': '5.11', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '374', 'groupId': 'OG000'}, {'value': '369', 'groupId': 'OG001'}, {'value': '204', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '6.67', 'spread': '4.6', 'groupId': 'OG000'}, {'value': '6.93', 'spread': '4.92', 'groupId': 'OG001'}, {'value': '8.46', 'spread': '5.09', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, week 1, week 2, week 3, week 4 (of intervention period), and 3 month follow-up', 'description': 'The PHQ-8 is an 8-item questionnaire where participants report how often in the past 2 weeks they were bothered by specific problems. It is scored on a 4-point Likert scale where 0 = not at all to 3 = nearly every day. The total possible range of scores is 0-24 where higher scores indicate more depressive symptoms.', 'unitOfMeasure': 'score on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time points.'}, {'type': 'SECONDARY', 'title': 'Anxiety Symptoms Measured by Generalized Anxiety Disorder - 7 (GAD-7) Score', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '8.94', 'spread': '4.95', 'groupId': 'OG000'}, {'value': '8.67', 'spread': '4.97', 'groupId': 'OG001'}, {'value': '8.37', 'spread': '4.97', 'groupId': 'OG002'}]}]}, {'title': 'Week 1', 'denoms': [{'units': 'Participants', 'counts': [{'value': '403', 'groupId': 'OG000'}, {'value': '407', 'groupId': 'OG001'}, {'value': '216', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '8.58', 'spread': '4.88', 'groupId': 'OG000'}, {'value': '8.13', 'spread': '4.97', 'groupId': 'OG001'}, {'value': '8.04', 'spread': '5.27', 'groupId': 'OG002'}]}]}, {'title': 'Week 2', 'denoms': [{'units': 'Participants', 'counts': [{'value': '376', 'groupId': 'OG000'}, {'value': '377', 'groupId': 'OG001'}, {'value': '204', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '7.66', 'spread': '4.66', 'groupId': 'OG000'}, {'value': '7.46', 'spread': '4.88', 'groupId': 'OG001'}, {'value': '7.68', 'spread': '5.04', 'groupId': 'OG002'}]}]}, {'title': 'Week 3', 'denoms': [{'units': 'Participants', 'counts': [{'value': '372', 'groupId': 'OG000'}, {'value': '366', 'groupId': 'OG001'}, {'value': '204', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '7.21', 'spread': '4.6', 'groupId': 'OG000'}, {'value': '7.15', 'spread': '4.71', 'groupId': 'OG001'}, {'value': '7.59', 'spread': '5.16', 'groupId': 'OG002'}]}]}, {'title': 'Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '395', 'groupId': 'OG000'}, {'value': '389', 'groupId': 'OG001'}, {'value': '218', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '6.39', 'spread': '4.55', 'groupId': 'OG000'}, {'value': '6.46', 'spread': '4.6', 'groupId': 'OG001'}, {'value': '7.28', 'spread': '5.19', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '373', 'groupId': 'OG000'}, {'value': '369', 'groupId': 'OG001'}, {'value': '204', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '6.1', 'spread': '4.63', 'groupId': 'OG000'}, {'value': '6.22', 'spread': '4.75', 'groupId': 'OG001'}, {'value': '7.08', 'spread': '5.09', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, week 1, week 2, week 3, week 4 (of intervention period), and 3 month follow-up', 'description': 'The GAD-7 is a 7-item questionnaire where participants report how often in the past 2 weeks they were bothered by specific problems. It is scored on a 4-point Likert scale where 0 = not at all to 3 = nearly every day. The total possible range of scores is 0-21 where higher scores indicate more anxious symptoms.', 'unitOfMeasure': 'score on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time points.'}, {'type': 'SECONDARY', 'title': 'Sleep Disturbance Measured by Patient-Reported Outcomes Measurement Information System (PROMIS) Sleep Disturbance Score', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '57.73', 'spread': '8.03', 'groupId': 'OG000'}, {'value': '56.94', 'spread': '8.16', 'groupId': 'OG001'}, {'value': '56.9', 'spread': '8.41', 'groupId': 'OG002'}]}]}, {'title': 'Week 1', 'denoms': [{'units': 'Participants', 'counts': [{'value': '402', 'groupId': 'OG000'}, {'value': '407', 'groupId': 'OG001'}, {'value': '215', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '56.26', 'spread': '8.35', 'groupId': 'OG000'}, {'value': '55.91', 'spread': '8.31', 'groupId': 'OG001'}, {'value': '57.12', 'spread': '8.67', 'groupId': 'OG002'}]}]}, {'title': 'Week 2', 'denoms': [{'units': 'Participants', 'counts': [{'value': '376', 'groupId': 'OG000'}, {'value': '377', 'groupId': 'OG001'}, {'value': '204', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '55.78', 'spread': '8.93', 'groupId': 'OG000'}, {'value': '55.48', 'spread': '8.04', 'groupId': 'OG001'}, {'value': '55.65', 'spread': '9.19', 'groupId': 'OG002'}]}]}, {'title': 'Week 3', 'denoms': [{'units': 'Participants', 'counts': [{'value': '371', 'groupId': 'OG000'}, {'value': '366', 'groupId': 'OG001'}, {'value': '204', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '55.14', 'spread': '9.24', 'groupId': 'OG000'}, {'value': '54.8', 'spread': '8.96', 'groupId': 'OG001'}, {'value': '56.53', 'spread': '8.95', 'groupId': 'OG002'}]}]}, {'title': 'Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '395', 'groupId': 'OG000'}, {'value': '389', 'groupId': 'OG001'}, {'value': '217', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '54.23', 'spread': '9.06', 'groupId': 'OG000'}, {'value': '54.17', 'spread': '8.76', 'groupId': 'OG001'}, {'value': '55.81', 'spread': '9.23', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '368', 'groupId': 'OG000'}, {'value': '368', 'groupId': 'OG001'}, {'value': '201', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '53.61', 'spread': '9.1', 'groupId': 'OG000'}, {'value': '53.51', 'spread': '9.29', 'groupId': 'OG001'}, {'value': '55.76', 'spread': '9.31', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, week 1, week 2, week 3, week 4 (of intervention period), and 3 month follow-up', 'description': 'The PROMIS Sleep Disturbance scale is a computer-adaptive measure where participants report how often in the past 7 days they had various sleep-related experiences (e.g., "my sleep was restful"). It is scored on a 5-point Likert scale where 1 = not at all to 5 = very much. It provides total scores as T-scores (mean = 50, standard deviation (SD) = 10) where higher scores indicate more sleep disturbance.', 'unitOfMeasure': 'T-score', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time points.'}, {'type': 'SECONDARY', 'title': 'Flourishing Measured by the Flourishing Index Score', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '56.26', 'spread': '15.33', 'groupId': 'OG000'}, {'value': '56.55', 'spread': '16.05', 'groupId': 'OG001'}, {'value': '56.63', 'spread': '15.22', 'groupId': 'OG002'}]}]}, {'title': 'Week 1', 'denoms': [{'units': 'Participants', 'counts': [{'value': '404', 'groupId': 'OG000'}, {'value': '408', 'groupId': 'OG001'}, {'value': '215', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '57.19', 'spread': '15.69', 'groupId': 'OG000'}, {'value': '57.52', 'spread': '15.83', 'groupId': 'OG001'}, {'value': '57.22', 'spread': '14.9', 'groupId': 'OG002'}]}]}, {'title': 'Week 2', 'denoms': [{'units': 'Participants', 'counts': [{'value': '377', 'groupId': 'OG000'}, {'value': '377', 'groupId': 'OG001'}, {'value': '204', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '60.11', 'spread': '15.58', 'groupId': 'OG000'}, {'value': '59.92', 'spread': '15.85', 'groupId': 'OG001'}, {'value': '58.18', 'spread': '16.38', 'groupId': 'OG002'}]}]}, {'title': 'Week 3', 'denoms': [{'units': 'Participants', 'counts': [{'value': '372', 'groupId': 'OG000'}, {'value': '365', 'groupId': 'OG001'}, {'value': '204', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '62.45', 'spread': '15.95', 'groupId': 'OG000'}, {'value': '60.87', 'spread': '15.77', 'groupId': 'OG001'}, {'value': '58.30', 'spread': '15.80', 'groupId': 'OG002'}]}]}, {'title': 'Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '395', 'groupId': 'OG000'}, {'value': '389', 'groupId': 'OG001'}, {'value': '218', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '64.53', 'spread': '16.54', 'groupId': 'OG000'}, {'value': '63.52', 'spread': '16.42', 'groupId': 'OG001'}, {'value': '59.29', 'spread': '16.43', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '374', 'groupId': 'OG000'}, {'value': '369', 'groupId': 'OG001'}, {'value': '203', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '66.00', 'spread': '16.58', 'groupId': 'OG000'}, {'value': '64.62', 'spread': '16.76', 'groupId': 'OG001'}, {'value': '60.99', 'spread': '15.43', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, week 1, week 2, week 3, week 4 (of intervention period), and 3 month follow-up', 'description': 'The Flourishing Index is a 10-item questionnaire where participants report their general level of flourishing (e.g., well-being, health, etc.). It is scored on a 0 to 10-point scale, with anchors varying across items. The total score ranges from 0 to 100 with higher scores indicating higher flourishing.', 'unitOfMeasure': 'score on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time-points'}, {'type': 'SECONDARY', 'title': 'Awareness Measured by Five Facet Mindfulness Questionnaire Acting With Awareness Subscale Score', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '24.11', 'spread': '6.13', 'groupId': 'OG000'}, {'value': '24.41', 'spread': '6.32', 'groupId': 'OG001'}, {'value': '23.95', 'spread': '6.57', 'groupId': 'OG002'}]}]}, {'title': 'Week 1', 'denoms': [{'units': 'Participants', 'counts': [{'value': '402', 'groupId': 'OG000'}, {'value': '407', 'groupId': 'OG001'}, {'value': '215', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '23.61', 'spread': '6.88', 'groupId': 'OG000'}, {'value': '24.26', 'spread': '6.91', 'groupId': 'OG001'}, {'value': '24.27', 'spread': '7.35', 'groupId': 'OG002'}]}]}, {'title': 'Week 2', 'denoms': [{'units': 'Participants', 'counts': [{'value': '376', 'groupId': 'OG000'}, {'value': '377', 'groupId': 'OG001'}, {'value': '204', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '24.55', 'spread': '7.1', 'groupId': 'OG000'}, {'value': '25.02', 'spread': '7.02', 'groupId': 'OG001'}, {'value': '24.63', 'spread': '7.29', 'groupId': 'OG002'}]}]}, {'title': 'Week 3', 'denoms': [{'units': 'Participants', 'counts': [{'value': '371', 'groupId': 'OG000'}, {'value': '366', 'groupId': 'OG001'}, {'value': '204', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '25.68', 'spread': '7.28', 'groupId': 'OG000'}, {'value': '25.95', 'spread': '7.4', 'groupId': 'OG001'}, {'value': '24.74', 'spread': '7.65', 'groupId': 'OG002'}]}]}, {'title': 'Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '395', 'groupId': 'OG000'}, {'value': '389', 'groupId': 'OG001'}, {'value': '217', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '25.89', 'spread': '6.74', 'groupId': 'OG000'}, {'value': '26.03', 'spread': '6.83', 'groupId': 'OG001'}, {'value': '24.68', 'spread': '6.92', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '369', 'groupId': 'OG000'}, {'value': '368', 'groupId': 'OG001'}, {'value': '203', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '26.09', 'spread': '6.78', 'groupId': 'OG000'}, {'value': '26.18', 'spread': '6.32', 'groupId': 'OG001'}, {'value': '24.75', 'spread': '6.75', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, week 1, week 2, week 3, week 4 (of intervention period), and 3 month follow-up', 'description': 'The Five Facet Mindfulness Questionnaire Acting with Awareness Subscale is a 8-item subscale where participants report on their general ability to focus. It is scored on a 5-point Likert scale where 1 = never or very rarely true to 5 = very often or always true. The total possible range of scores is 8-40 where higher scores indicate a greater ability to focus.', 'unitOfMeasure': 'score on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time points.'}, {'type': 'SECONDARY', 'title': 'Connection Measured by NIH Toolbox Loneliness Score', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '15.1', 'spread': '4.85', 'groupId': 'OG000'}, {'value': '14.74', 'spread': '4.63', 'groupId': 'OG001'}, {'value': '15.13', 'spread': '4.66', 'groupId': 'OG002'}]}]}, {'title': 'Week 1', 'denoms': [{'units': 'Participants', 'counts': [{'value': '402', 'groupId': 'OG000'}, {'value': '407', 'groupId': 'OG001'}, {'value': '215', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '14.33', 'spread': '5.11', 'groupId': 'OG000'}, {'value': '13.97', 'spread': '4.82', 'groupId': 'OG001'}, {'value': '14.57', 'spread': '4.81', 'groupId': 'OG002'}]}]}, {'title': 'Week 2', 'denoms': [{'units': 'Participants', 'counts': [{'value': '376', 'groupId': 'OG000'}, {'value': '377', 'groupId': 'OG001'}, {'value': '204', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '13.52', 'spread': '5.14', 'groupId': 'OG000'}, {'value': '13.24', 'spread': '4.64', 'groupId': 'OG001'}, {'value': '13.86', 'spread': '4.98', 'groupId': 'OG002'}]}]}, {'title': 'Week 3', 'denoms': [{'units': 'Participants', 'counts': [{'value': '371', 'groupId': 'OG000'}, {'value': '366', 'groupId': 'OG001'}, {'value': '204', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '13.05', 'spread': '5.28', 'groupId': 'OG000'}, {'value': '13.00', 'spread': '4.79', 'groupId': 'OG001'}, {'value': '14.21', 'spread': '4.85', 'groupId': 'OG002'}]}]}, {'title': 'Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '395', 'groupId': 'OG000'}, {'value': '389', 'groupId': 'OG001'}, {'value': '217', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '12.54', 'spread': '5.30', 'groupId': 'OG000'}, {'value': '12.41', 'spread': '4.74', 'groupId': 'OG001'}, {'value': '14.16', 'spread': '4.73', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '369', 'groupId': 'OG000'}, {'value': '368', 'groupId': 'OG001'}, {'value': '203', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '12.31', 'spread': '5.11', 'groupId': 'OG000'}, {'value': '12.82', 'spread': '4.96', 'groupId': 'OG001'}, {'value': '14.10', 'spread': '4.81', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, week 1, week 2, week 3, week 4 (of intervention period), and 3 month follow-up', 'description': 'The NIH Toolbox Loneliness is a 5-item questionnaire where participants report how often in the past week they have felt loneliness. It is scored on a 5-point Likert scale where 1 = never to 5 = always. The total possible range of scores is 5-25 where higher scores indicate a greater sense of loneliness.', 'unitOfMeasure': 'score on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time points.'}, {'type': 'SECONDARY', 'title': 'Decentering Measured by Decentering Subscale of Experiencing Questionnaire Scale Score', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '33.12', 'spread': '6.65', 'groupId': 'OG000'}, {'value': '33.22', 'spread': '6.95', 'groupId': 'OG001'}, {'value': '33.51', 'spread': '7.40', 'groupId': 'OG002'}]}]}, {'title': 'Week 1', 'denoms': [{'units': 'Participants', 'counts': [{'value': '401', 'groupId': 'OG000'}, {'value': '407', 'groupId': 'OG001'}, {'value': '214', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '34.15', 'spread': '6.31', 'groupId': 'OG000'}, {'value': '33.92', 'spread': '6.42', 'groupId': 'OG001'}, {'value': '33.99', 'spread': '6.94', 'groupId': 'OG002'}]}]}, {'title': 'Week 2', 'denoms': [{'units': 'Participants', 'counts': [{'value': '376', 'groupId': 'OG000'}, {'value': '377', 'groupId': 'OG001'}, {'value': '204', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '36.49', 'spread': '6.14', 'groupId': 'OG000'}, {'value': '35.74', 'spread': '6.40', 'groupId': 'OG001'}, {'value': '34.43', 'spread': '6.70', 'groupId': 'OG002'}]}]}, {'title': 'Week 3', 'denoms': [{'units': 'Participants', 'counts': [{'value': '371', 'groupId': 'OG000'}, {'value': '366', 'groupId': 'OG001'}, {'value': '203', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '37.46', 'spread': '6.46', 'groupId': 'OG000'}, {'value': '36.69', 'spread': '6.67', 'groupId': 'OG001'}, {'value': '34.74', 'spread': '6.65', 'groupId': 'OG002'}]}]}, {'title': 'Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '395', 'groupId': 'OG000'}, {'value': '387', 'groupId': 'OG001'}, {'value': '217', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '39.05', 'spread': '6.98', 'groupId': 'OG000'}, {'value': '37.94', 'spread': '7.17', 'groupId': 'OG001'}, {'value': '34.67', 'spread': '6.96', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '367', 'groupId': 'OG000'}, {'value': '367', 'groupId': 'OG001'}, {'value': '200', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '39.26', 'spread': '7.37', 'groupId': 'OG000'}, {'value': '38.37', 'spread': '7.42', 'groupId': 'OG001'}, {'value': '35.55', 'spread': '7.04', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, week 1, week 2, week 3, week 4 (of intervention period), and 3 month follow-up', 'description': 'The Decentering subscale of the Experience Questionnaire is an 11-item questionnaire where participants report on their ability to decenter from their experience. It is scored on a 5-point Likert scale where 1 = never to 5 = all the time. The total possible range of scores is 11-55 where higher scores indicate a greater ability to decenter from experience.', 'unitOfMeasure': 'score on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time points.'}, {'type': 'SECONDARY', 'title': 'Meaning in Life Measured by NIH Toolbox Meaning and Purpose Score', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '43.44', 'spread': '9.89', 'groupId': 'OG000'}, {'value': '43.09', 'spread': '9.78', 'groupId': 'OG001'}, {'value': '43.33', 'spread': '9.76', 'groupId': 'OG002'}]}]}, {'title': 'Week 1', 'denoms': [{'units': 'Participants', 'counts': [{'value': '402', 'groupId': 'OG000'}, {'value': '407', 'groupId': 'OG001'}, {'value': '215', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '42.89', 'spread': '9.64', 'groupId': 'OG000'}, {'value': '42.59', 'spread': '9.74', 'groupId': 'OG001'}, {'value': '41.58', 'spread': '9.67', 'groupId': 'OG002'}]}]}, {'title': 'Week 2', 'denoms': [{'units': 'Participants', 'counts': [{'value': '376', 'groupId': 'OG000'}, {'value': '377', 'groupId': 'OG001'}, {'value': '204', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '44.07', 'spread': '9.89', 'groupId': 'OG000'}, {'value': '43.66', 'spread': '9.96', 'groupId': 'OG001'}, {'value': '41.71', 'spread': '11.03', 'groupId': 'OG002'}]}]}, {'title': 'Week 3', 'denoms': [{'units': 'Participants', 'counts': [{'value': '371', 'groupId': 'OG000'}, {'value': '366', 'groupId': 'OG001'}, {'value': '204', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '44.98', 'spread': '10.25', 'groupId': 'OG000'}, {'value': '44.27', 'spread': '10.47', 'groupId': 'OG001'}, {'value': '41.96', 'spread': '10.61', 'groupId': 'OG002'}]}]}, {'title': 'Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '395', 'groupId': 'OG000'}, {'value': '389', 'groupId': 'OG001'}, {'value': '217', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '46.86', 'spread': '11.07', 'groupId': 'OG000'}, {'value': '45.74', 'spread': '10.63', 'groupId': 'OG001'}, {'value': '42.88', 'spread': '10.47', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '368', 'groupId': 'OG000'}, {'value': '368', 'groupId': 'OG001'}, {'value': '202', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '47.64', 'spread': '10.93', 'groupId': 'OG000'}, {'value': '46.19', 'spread': '10.69', 'groupId': 'OG001'}, {'value': '44.21', 'spread': '10.60', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, week 1, week 2, week 3, week 4 (of intervention period), and 3 month follow-up', 'description': 'The PROMIS / NIH Toolbox Meaning and Purpose is a computer-adaptive measure where participants report how much meaning and purpose they experience in life (e.g., "I understand my life\'s meaning"). It is scored on a 5-point Likert scale where 1 = strongly disagree to 5 = strongly agree. It provides total scores as T-scores (mean = 50, SD = 10) where higher scores indicate more meaning and purpose in life.', 'unitOfMeasure': 'T-score', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time points.'}, {'type': 'SECONDARY', 'title': 'Pain Intensity Measured by PROMIS Pain Intensity Score', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '3.22', 'spread': '2.54', 'groupId': 'OG000'}, {'value': '3.33', 'spread': '2.53', 'groupId': 'OG001'}, {'value': '3.42', 'spread': '2.59', 'groupId': 'OG002'}]}]}, {'title': 'Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '395', 'groupId': 'OG000'}, {'value': '389', 'groupId': 'OG001'}, {'value': '217', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '2.98', 'spread': '2.6', 'groupId': 'OG000'}, {'value': '3.12', 'spread': '2.57', 'groupId': 'OG001'}, {'value': '3.5', 'spread': '2.81', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '367', 'groupId': 'OG000'}, {'value': '368', 'groupId': 'OG001'}, {'value': '201', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '3.11', 'spread': '2.63', 'groupId': 'OG000'}, {'value': '3.07', 'spread': '2.59', 'groupId': 'OG001'}, {'value': '3.39', 'spread': '2.73', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, week 4 (of intervention period), and 3 month follow-up', 'description': 'The single-item PROMIS Pain Intensity scale is a 1-item scale where participants report on their pain intensity in the past 7 days. It is scored on an 11-point Likert-scale where 0 = no pain and 10 = worst pain imaginable. Scores range from 0 to 10, with higher scores indicating higher pain intensity', 'unitOfMeasure': 'score on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time points.'}, {'type': 'SECONDARY', 'title': 'Pain Interference Measured by PROMIS Pain Inference Scale Score', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '52.94', 'spread': '10.27', 'groupId': 'OG000'}, {'value': '53.6', 'spread': '10.17', 'groupId': 'OG001'}, {'value': '53.57', 'spread': '10.51', 'groupId': 'OG002'}]}]}, {'title': 'Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '395', 'groupId': 'OG000'}, {'value': '389', 'groupId': 'OG001'}, {'value': '217', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '51.65', 'spread': '10.55', 'groupId': 'OG000'}, {'value': '51.66', 'spread': '9.81', 'groupId': 'OG001'}, {'value': '53.16', 'spread': '10.91', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '368', 'groupId': 'OG000'}, {'value': '368', 'groupId': 'OG001'}, {'value': '201', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '52.21', 'spread': '10.65', 'groupId': 'OG000'}, {'value': '52.13', 'spread': '10.17', 'groupId': 'OG001'}, {'value': '52.96', 'spread': '11.06', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, week 4 (of intervention period), and 3 month follow-up', 'description': 'The PROMIS Pain Interference scale is a computer-adaptive measure where participants report how often in the past 7 days they had pain-related interference in their life (e.g., "how much did pain interfere with your enjoyment of life"). It is scored on a 5-point Likert scale where 1 = not at all to 5 = very much. It provides total scores as T-scores (mean = 50, SD = 10) where higher scores indicate more pain interference.', 'unitOfMeasure': 'T-score', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time points.'}, {'type': 'SECONDARY', 'title': 'Nonjudgment Measured by Five Facet Mindfulness Questionnaire Nonjudgment Subscale Score', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '24.62', 'spread': '7.05', 'groupId': 'OG000'}, {'value': '24.35', 'spread': '6.88', 'groupId': 'OG001'}, {'value': '23.92', 'spread': '6.89', 'groupId': 'OG002'}]}]}, {'title': 'Week 1', 'denoms': [{'units': 'Participants', 'counts': [{'value': '402', 'groupId': 'OG000'}, {'value': '407', 'groupId': 'OG001'}, {'value': '215', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '26.24', 'spread': '7.45', 'groupId': 'OG000'}, {'value': '26.32', 'spread': '7.47', 'groupId': 'OG001'}, {'value': '25.84', 'spread': '7.80', 'groupId': 'OG002'}]}]}, {'title': 'Week 2', 'denoms': [{'units': 'Participants', 'counts': [{'value': '376', 'groupId': 'OG000'}, {'value': '377', 'groupId': 'OG001'}, {'value': '204', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '27.98', 'spread': '7.46', 'groupId': 'OG000'}, {'value': '27.46', 'spread': '7.55', 'groupId': 'OG001'}, {'value': '26.88', 'spread': '7.67', 'groupId': 'OG002'}]}]}, {'title': 'Week 3', 'denoms': [{'units': 'Participants', 'counts': [{'value': '371', 'groupId': 'OG000'}, {'value': '366', 'groupId': 'OG001'}, {'value': '204', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '29.53', 'spread': '7.50', 'groupId': 'OG000'}, {'value': '28.57', 'spread': '7.68', 'groupId': 'OG001'}, {'value': '26.99', 'spread': '7.97', 'groupId': 'OG002'}]}]}, {'title': 'Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '395', 'groupId': 'OG000'}, {'value': '389', 'groupId': 'OG001'}, {'value': '217', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '28.93', 'spread': '6.86', 'groupId': 'OG000'}, {'value': '28.16', 'spread': '6.90', 'groupId': 'OG001'}, {'value': '26.35', 'spread': '7.62', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '369', 'groupId': 'OG000'}, {'value': '368', 'groupId': 'OG001'}, {'value': '203', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '28.89', 'spread': '6.77', 'groupId': 'OG000'}, {'value': '27.83', 'spread': '6.95', 'groupId': 'OG001'}, {'value': '26.12', 'spread': '7.42', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, week 1, week 2, week 3, week 4 (of intervention period), and 3 month follow-up', 'description': 'The Five Facet Mindfulness Questionnaire Nonjudgment Subscale is a 8-item subscale where participants report on their nonjudgment of experience in daily life. It is scored on a 5-point Likert scale where 1 = never or very rarely true to 5 = very often or always true. The total possible range of scores is 8-40 where higher scores indicate a greater nonjudgment of experience.', 'unitOfMeasure': 'score on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time points.'}, {'type': 'SECONDARY', 'title': 'Climate Change Anxiety Scale', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '21.17', 'spread': '7.02', 'groupId': 'OG000'}, {'value': '20.98', 'spread': '7.54', 'groupId': 'OG001'}, {'value': '21.22', 'spread': '7.91', 'groupId': 'OG002'}]}]}, {'title': 'Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '395', 'groupId': 'OG000'}, {'value': '387', 'groupId': 'OG001'}, {'value': '217', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '20.79', 'spread': '6.95', 'groupId': 'OG000'}, {'value': '20.67', 'spread': '7.51', 'groupId': 'OG001'}, {'value': '21.01', 'spread': '8.18', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '367', 'groupId': 'OG000'}, {'value': '367', 'groupId': 'OG001'}, {'value': '200', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '20.5', 'spread': '6.68', 'groupId': 'OG000'}, {'value': '20.34', 'spread': '7.74', 'groupId': 'OG001'}, {'value': '20.18', 'spread': '8.33', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, week 4, and 3 month follow up', 'description': 'The Climate Change Anxiety Scale is a 13-item scale where participants report their anxiety regarding climate change (e.g., "I have nightmares about climate change"). It is scored on a 5-point Likert scale where 1 = "never" to 5 = "almost always." Total scores range from 13 to 65 where higher scores indicate greater climate change anxiety.', 'unitOfMeasure': 'score on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time points.'}, {'type': 'SECONDARY', 'title': 'Wellbeing Growth Mindset', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '14.27', 'spread': '2.83', 'groupId': 'OG000'}, {'value': '14.07', 'spread': '2.89', 'groupId': 'OG001'}, {'value': '13.88', 'spread': '3.17', 'groupId': 'OG002'}]}]}, {'title': 'Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '395', 'groupId': 'OG000'}, {'value': '389', 'groupId': 'OG001'}, {'value': '218', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '14.61', 'spread': '2.90', 'groupId': 'OG000'}, {'value': '14.46', 'spread': '2.70', 'groupId': 'OG001'}, {'value': '13.50', 'spread': '3.23', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '371', 'groupId': 'OG000'}, {'value': '368', 'groupId': 'OG001'}, {'value': '203', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '14.31', 'spread': '2.93', 'groupId': 'OG000'}, {'value': '14.04', 'spread': '3.10', 'groupId': 'OG001'}, {'value': '13.54', 'spread': '3.12', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, week 4, and 3 month follow up', 'description': 'The Wellbeing Growth Mindset scale is a 3-item scale where participants report whether they believe wellbeing is malleable (e.g., "Your well-being is something about you that you can\'t change very much."). It is scored on a 6-point Likert scale where 1 = "strongly disagree" to 6 = "strongly agree." Total scores range from 3 to 18 where higher scores indicate greater wellbeing growth mindset.', 'unitOfMeasure': 'score on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time points.'}, {'type': 'SECONDARY', 'title': 'Healthy Minds Index (HM Index) - Awareness', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '9.13', 'spread': '2.72', 'groupId': 'OG000'}, {'value': '9.11', 'spread': '2.8', 'groupId': 'OG001'}, {'value': '9.01', 'spread': '2.86', 'groupId': 'OG002'}]}]}, {'title': 'Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '395', 'groupId': 'OG000'}, {'value': '389', 'groupId': 'OG001'}, {'value': '218', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '9.55', 'spread': '2.75', 'groupId': 'OG000'}, {'value': '9.33', 'spread': '2.94', 'groupId': 'OG001'}, {'value': '8.72', 'spread': '2.91', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '371', 'groupId': 'OG000'}, {'value': '369', 'groupId': 'OG001'}, {'value': '203', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '9.72', 'spread': '2.78', 'groupId': 'OG000'}, {'value': '9.5', 'spread': '2.88', 'groupId': 'OG001'}, {'value': '8.89', 'spread': '2.76', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, week 4, and 3 month follow up', 'description': 'The HM Index is a 17-item questionnaire assessing qualities trained in the HMP app (awareness, connection, insight, purpose). It is scored on a 0- to 4-point Likert scale where 0 = a low amount (e.g., never, not at all, none of the time) and 4 = a higher amount (e.g., always, to the highest degree, all of the time) of a particular quality. Total scores for the Awareness subscale is 0 to 16 where higher scores indicate more awareness.', 'unitOfMeasure': 'score on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time points.'}, {'type': 'SECONDARY', 'title': 'Healthy Minds Index (HM Index) - Connection', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '15.67', 'spread': '3.79', 'groupId': 'OG000'}, {'value': '15.65', 'spread': '3.49', 'groupId': 'OG001'}, {'value': '15.64', 'spread': '3.64', 'groupId': 'OG002'}]}]}, {'title': 'Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '395', 'groupId': 'OG000'}, {'value': '389', 'groupId': 'OG001'}, {'value': '218', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '16.03', 'spread': '4.03', 'groupId': 'OG000'}, {'value': '16.16', 'spread': '3.86', 'groupId': 'OG001'}, {'value': '15.16', 'spread': '3.72', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '371', 'groupId': 'OG000'}, {'value': '369', 'groupId': 'OG001'}, {'value': '203', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '15.88', 'spread': '4.02', 'groupId': 'OG000'}, {'value': '16.03', 'spread': '3.81', 'groupId': 'OG001'}, {'value': '15.08', 'spread': '3.94', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, week 4, and 3 month follow up', 'description': 'The HM Index is a 17-item questionnaire assessing qualities trained in the HMP app (awareness, connection, insight, purpose). It is scored on a 0- to 4-point Likert scale where 0 = a low amount (e.g., never, not at all, none of the time) and 4 = a higher amount (e.g., always, to the highest degree, all of the time) of a particular quality. Total scores for the Connection subscale range from 0 to 24, where higher scores indicate more connection.', 'unitOfMeasure': 'score on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time points.'}, {'type': 'SECONDARY', 'title': 'Healthy Minds Index (HM Index) - Insight', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '5.79', 'spread': '2.3', 'groupId': 'OG000'}, {'value': '5.76', 'spread': '2.44', 'groupId': 'OG001'}, {'value': '6.03', 'spread': '2.24', 'groupId': 'OG002'}]}]}, {'title': 'Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '395', 'groupId': 'OG000'}, {'value': '389', 'groupId': 'OG001'}, {'value': '218', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '6.78', 'spread': '2.31', 'groupId': 'OG000'}, {'value': '6.71', 'spread': '2.29', 'groupId': 'OG001'}, {'value': '6.07', 'spread': '2.16', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '371', 'groupId': 'OG000'}, {'value': '369', 'groupId': 'OG001'}, {'value': '203', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '6.86', 'spread': '2.34', 'groupId': 'OG000'}, {'value': '6.89', 'spread': '2.23', 'groupId': 'OG001'}, {'value': '6.08', 'spread': '2.26', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, week 4, and 3 month follow up', 'description': 'The HM Index is a 17-item questionnaire assessing qualities trained in the HMP app (awareness, connection, insight, purpose). It is scored on a 0- to 4-point Likert scale where 0 = a low amount (e.g., never, not at all, none of the time) and 4 = a higher amount (e.g., always, to the highest degree, all of the time) of a particular quality. Total scores for the Insight subscale range from 0 to 12, where higher scores indicate more insight.', 'unitOfMeasure': 'score on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time points.'}, {'type': 'SECONDARY', 'title': 'Healthy Minds Index (HM Index) - Purpose', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '9.07', 'spread': '3.57', 'groupId': 'OG000'}, {'value': '8.8', 'spread': '3.71', 'groupId': 'OG001'}, {'value': '9.22', 'spread': '3.61', 'groupId': 'OG002'}]}]}, {'title': 'Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '395', 'groupId': 'OG000'}, {'value': '389', 'groupId': 'OG001'}, {'value': '218', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '10.19', 'spread': '3.47', 'groupId': 'OG000'}, {'value': '10.05', 'spread': '3.56', 'groupId': 'OG001'}, {'value': '8.95', 'spread': '3.61', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '371', 'groupId': 'OG000'}, {'value': '369', 'groupId': 'OG001'}, {'value': '203', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '10.48', 'spread': '3.34', 'groupId': 'OG000'}, {'value': '10.16', 'spread': '3.56', 'groupId': 'OG001'}, {'value': '9.43', 'spread': '3.95', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, week 4, and 3 month follow up', 'description': 'The HM Index is a 17-item questionnaire assessing qualities trained in the HMP app (awareness, connection, insight, purpose). It is scored on a 0- to 4-point Likert scale where 0 = a low amount (e.g., never, not at all, none of the time) and 4 = a higher amount (e.g., always, to the highest degree, all of the time) of a particular quality. Total scores for the Purpose subscale range from 0 to 16, where higher scores indicate more purpose.', 'unitOfMeasure': 'score on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time points.'}, {'type': 'SECONDARY', 'title': 'Life Orientation Test - Revised', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '11.78', 'spread': '4.97', 'groupId': 'OG000'}, {'value': '11.71', 'spread': '4.72', 'groupId': 'OG001'}, {'value': '11.77', 'spread': '5.21', 'groupId': 'OG002'}]}]}, {'title': 'Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '395', 'groupId': 'OG000'}, {'value': '389', 'groupId': 'OG001'}, {'value': '217', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '13.42', 'spread': '5.02', 'groupId': 'OG000'}, {'value': '13.01', 'spread': '4.73', 'groupId': 'OG001'}, {'value': '12.23', 'spread': '4.98', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '368', 'groupId': 'OG000'}, {'value': '368', 'groupId': 'OG001'}, {'value': '202', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '13.73', 'spread': '5.13', 'groupId': 'OG000'}, {'value': '13.17', 'spread': '4.83', 'groupId': 'OG001'}, {'value': '12.22', 'spread': '5.32', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, week 4, and 3 month follow up', 'description': 'The Life Orientation Test - Revised is a 6-item scale where participants report their level of optimism (e.g., "In uncertain times, I usually expect the best"). It is scored on a 5-point Likert scale where 0 = "strongly disagree" to 4 = "strongly agree." Total scores range from 0 to 24 where higher scores indicate greater optimism.', 'unitOfMeasure': 'score on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time points.'}, {'type': 'SECONDARY', 'title': 'Perceived Stress Scale', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '29.7', 'spread': '6.77', 'groupId': 'OG000'}, {'value': '29.51', 'spread': '6.29', 'groupId': 'OG001'}, {'value': '29.72', 'spread': '6.64', 'groupId': 'OG002'}]}]}, {'title': 'Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '395', 'groupId': 'OG000'}, {'value': '389', 'groupId': 'OG001'}, {'value': '217', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '26.46', 'spread': '6.82', 'groupId': 'OG000'}, {'value': '26.90', 'spread': '6.54', 'groupId': 'OG001'}, {'value': '29.17', 'spread': '6.54', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '68', 'groupId': 'OG000'}, {'value': '368', 'groupId': 'OG001'}, {'value': '201', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '25.70', 'spread': '7.37', 'groupId': 'OG000'}, {'value': '26.03', 'spread': '7.10', 'groupId': 'OG001'}, {'value': '28.45', 'spread': '7.11', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, week 4, and 3 month follow up', 'description': 'The Perceived Stress Scale is a 10-item scale where participants report their level of perceived stress (e.g., "In the last month, how often have you felt nervous and \'stressed\'?"). It is scored on a 5-point Likert scale where 0 = "never" to 4 = "very often." Total scores range from 0 to 40 where higher scores indicate greater perceived stress.', 'unitOfMeasure': 'score on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time points.'}, {'type': 'SECONDARY', 'title': 'Perseverative Thinking Questionnaire', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '32.02', 'spread': '11.34', 'groupId': 'OG000'}, {'value': '31.14', 'spread': '11.56', 'groupId': 'OG001'}, {'value': '31.56', 'spread': '11.83', 'groupId': 'OG002'}]}]}, {'title': '4 week', 'denoms': [{'units': 'Participants', 'counts': [{'value': '395', 'groupId': 'OG000'}, {'value': '388', 'groupId': 'OG001'}, {'value': '217', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '26.94', 'spread': '11.90', 'groupId': 'OG000'}, {'value': '27.08', 'spread': '11.59', 'groupId': 'OG001'}, {'value': '30.69', 'spread': '11.93', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '367', 'groupId': 'OG000'}, {'value': '368', 'groupId': 'OG001'}, {'value': '200', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '25.39', 'spread': '12.40', 'groupId': 'OG000'}, {'value': '26.48', 'spread': '12.03', 'groupId': 'OG001'}, {'value': '29.28', 'spread': '12.55', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, week 4, and 3 month follow up', 'description': 'The Perseverative Thinking Questionnaire is a 15-item scale where participants report their level of repetitive negative thinking (e.g., "My thoughts repeat themselves"). It is scored on a 5-point Likert scale where 0 = "never" to 4 = "almost always." Total scores range from 0 to 60 where higher scores indicate greater perseverative thinking.', 'unitOfMeasure': 'score on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time points.'}, {'type': 'SECONDARY', 'title': 'Satisfaction With Life Scale', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '17.25', 'spread': '7.30', 'groupId': 'OG000'}, {'value': '17.27', 'spread': '7.24', 'groupId': 'OG001'}, {'value': '17.08', 'spread': '7.22', 'groupId': 'OG002'}]}]}, {'title': 'Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '395', 'groupId': 'OG000'}, {'value': '389', 'groupId': 'OG001'}, {'value': '217', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '19.62', 'spread': '7.72', 'groupId': 'OG000'}, {'value': '19.40', 'spread': '7.37', 'groupId': 'OG001'}, {'value': '17.51', 'spread': '7.47', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '368', 'groupId': 'OG000'}, {'value': '368', 'groupId': 'OG001'}, {'value': '201', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '20.33', 'spread': '7.81', 'groupId': 'OG000'}, {'value': '19.94', 'spread': '7.61', 'groupId': 'OG001'}, {'value': '18.04', 'spread': '7.42', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, week 4, and 3 month follow up', 'description': 'The Satisfaction with Life Scale is a 5-item scale where participants report their level of satisfaction with life (e.g., "In most ways my life is close to ideal"). It is scored on a 7-point Likert scale where 1 = "strongly disagree" to 7 = "strongly agree." Total scores range from 5 to 35 where higher scores indicate greater satisfaction with life.', 'unitOfMeasure': 'score on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time points.'}, {'type': 'SECONDARY', 'title': 'Subjective Happiness Scale', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '16.45', 'spread': '4.96', 'groupId': 'OG000'}, {'value': '16.53', 'spread': '5.25', 'groupId': 'OG001'}, {'value': '16.29', 'spread': '4.93', 'groupId': 'OG002'}]}]}, {'title': 'Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '395', 'groupId': 'OG000'}, {'value': '388', 'groupId': 'OG001'}, {'value': '217', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '17.91', 'spread': '5.14', 'groupId': 'OG000'}, {'value': '17.36', 'spread': '5.24', 'groupId': 'OG001'}, {'value': '16.35', 'spread': '4.94', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '367', 'groupId': 'OG000'}, {'value': '368', 'groupId': 'OG001'}, {'value': '201', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '18.20', 'spread': '5.31', 'groupId': 'OG000'}, {'value': '17.77', 'spread': '5.54', 'groupId': 'OG001'}, {'value': '16.62', 'spread': '4.93', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, week 4, and 3 month follow up', 'description': 'The Subjective Happiness Scale is a 4-item scale where participants report their level of subjective happiness (e.g., "In general, I consider myself \\[not a very happy person, a very happy person\\]"). It is scored on a 7-point Likert scale where 1 = less happy to 7 = more happy. Total scores range from 4 to 28 where higher scores indicate greater subjective happiness.', 'unitOfMeasure': 'score on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time points.'}, {'type': 'SECONDARY', 'title': 'Problematic and Risky Internet Use Screening Scale (PRIUSS-3)', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '201', 'groupId': 'OG000'}, {'value': '202', 'groupId': 'OG001'}, {'value': '101', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '4.79', 'spread': '2.68', 'groupId': 'OG000'}, {'value': '4.45', 'spread': '2.74', 'groupId': 'OG001'}, {'value': '4.42', 'spread': '2.87', 'groupId': 'OG002'}]}]}, {'title': 'Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '204', 'groupId': 'OG000'}, {'value': '191', 'groupId': 'OG001'}, {'value': '113', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '3.96', 'spread': '2.83', 'groupId': 'OG000'}, {'value': '3.97', 'spread': '2.76', 'groupId': 'OG001'}, {'value': '4.94', 'spread': '3.15', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '250', 'groupId': 'OG000'}, {'value': '253', 'groupId': 'OG001'}, {'value': '136', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '3.81', 'spread': '2.75', 'groupId': 'OG000'}, {'value': '3.63', 'spread': '2.61', 'groupId': 'OG001'}, {'value': '4.50', 'spread': '2.82', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, week 4, and 3 month follow up', 'description': 'The PRIUSS-3 is a 3-item scale where participants report their level of problematic internet use. It is scored on a 4-point Likert scale where 0 = never to 4 = very often. Total scores range from 0 to 12, where higher scores indicate more problematic internet use.', 'unitOfMeasure': 'score on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time points.'}, {'type': 'OTHER_PRE_SPECIFIED', 'title': 'Inflammatory Biomarkers: C-reactive Protein (CRP)', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '340', 'groupId': 'OG000'}, {'value': '341', 'groupId': 'OG001'}, {'value': '177', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '2.34', 'spread': '3.99', 'groupId': 'OG000'}, {'value': '2.68', 'spread': '4.16', 'groupId': 'OG001'}, {'value': '2.67', 'spread': '2.43', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '337', 'groupId': 'OG000'}, {'value': '338', 'groupId': 'OG001'}, {'value': '175', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '2.56', 'spread': '4.17', 'groupId': 'OG000'}, {'value': '2.89', 'spread': '4.55', 'groupId': 'OG001'}, {'value': '2.60', 'spread': '4.05', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline and 3 month follow-up', 'description': 'Dried blood spot samples will be used to measure two inflammatory cytokines (C-reactive protein (CRP) and interleukin-6 (IL-6)). Additionally mRNA assays will be used to detect and quantify inflammatory gene expression detect and monitor cellular immune responses. Analyses will focus on transcripts from \\~200 genes known to be involved in the regulation of inflammation, and will consider key transcripts (e.g., IL-1beta, TNF-alpha) as well as summary measures reflecting the activity of transcriptional networks that coordinate inflammation (NF-kB, AP-1).', 'unitOfMeasure': 'mg/L', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Data not provided or evaluable from all participants at all time points'}, {'type': 'OTHER_PRE_SPECIFIED', 'title': 'Inflammatory Biomarkers: TNF-Alpha, IL-6, Il-10', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'TNF-Alpha at baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '321', 'groupId': 'OG000'}, {'value': '328', 'groupId': 'OG001'}, {'value': '171', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '2.12', 'spread': '7.08', 'groupId': 'OG000'}, {'value': '1.69', 'spread': '0.85', 'groupId': 'OG001'}, {'value': '1.75', 'spread': '0.79', 'groupId': 'OG002'}]}]}, {'title': 'TNF-Alpha at 3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '321', 'groupId': 'OG000'}, {'value': '323', 'groupId': 'OG001'}, {'value': '167', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '1.83', 'spread': '3.71', 'groupId': 'OG000'}, {'value': '1.62', 'spread': '0.83', 'groupId': 'OG001'}, {'value': '2.02', 'spread': '3.11', 'groupId': 'OG002'}]}]}, {'title': 'IL-6 at baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '320', 'groupId': 'OG000'}, {'value': '328', 'groupId': 'OG001'}, {'value': '171', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '0.81', 'spread': '6.94', 'groupId': 'OG000'}, {'value': '0.33', 'spread': '0.36', 'groupId': 'OG001'}, {'value': '0.36', 'spread': '0.48', 'groupId': 'OG002'}]}]}, {'title': 'IL-6 at 3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '321', 'groupId': 'OG000'}, {'value': '323', 'groupId': 'OG001'}, {'value': '167', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '0.81', 'spread': '5.18', 'groupId': 'OG000'}, {'value': '0.37', 'spread': '0.68', 'groupId': 'OG001'}, {'value': '0.73', 'spread': '2.95', 'groupId': 'OG002'}]}]}, {'title': 'IL-10 at baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '321', 'groupId': 'OG000'}, {'value': '328', 'groupId': 'OG001'}, {'value': '171', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '0.12', 'spread': '0.19', 'groupId': 'OG000'}, {'value': '0.13', 'spread': '0.23', 'groupId': 'OG001'}, {'value': '0.36', 'spread': '2.76', 'groupId': 'OG002'}]}]}, {'title': 'IL-10 at 3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '320', 'groupId': 'OG000'}, {'value': '322', 'groupId': 'OG001'}, {'value': '167', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '0.13', 'spread': '0.20', 'groupId': 'OG000'}, {'value': '0.14', 'spread': '0.25', 'groupId': 'OG001'}, {'value': '0.37', 'spread': '2.81', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline and 3 month follow-up', 'description': 'Dried blood spot samples will be used to measure two inflammatory cytokines (C-reactive protein (CRP) and interleukin-6 (IL-6)). Additionally mRNA assays will be used to detect and quantify inflammatory gene expression detect and monitor cellular immune responses. Analyses will focus on transcripts from \\~200 genes known to be involved in the regulation of inflammation, and will consider key transcripts (e.g., IL-1beta, TNF-alpha) as well as summary measures reflecting the activity of transcriptional networks that coordinate inflammation (NF-kB, AP-1).', 'unitOfMeasure': 'pg/mL', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Data not provided or evaluable from all participants at all time points'}, {'type': 'OTHER_PRE_SPECIFIED', 'title': 'Microbiome Alpha Diversity: Species Richness', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'Observed at baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '342', 'groupId': 'OG000'}, {'value': '344', 'groupId': 'OG001'}, {'value': '176', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '308.78', 'spread': '122.78', 'groupId': 'OG000'}, {'value': '300.80', 'spread': '117.87', 'groupId': 'OG001'}, {'value': '312.68', 'spread': '114.24', 'groupId': 'OG002'}]}]}, {'title': 'Observed at 3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '331', 'groupId': 'OG000'}, {'value': '329', 'groupId': 'OG001'}, {'value': '174', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '303.48', 'spread': '120.49', 'groupId': 'OG000'}, {'value': '300.88', 'spread': '116.95', 'groupId': 'OG001'}, {'value': '311.52', 'spread': '115.26', 'groupId': 'OG002'}]}]}, {'title': 'Calculated at baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '342', 'groupId': 'OG000'}, {'value': '344', 'groupId': 'OG001'}, {'value': '176', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '309.89', 'spread': '123.30', 'groupId': 'OG000'}, {'value': '301.88', 'spread': '118.55', 'groupId': 'OG001'}, {'value': '313.87', 'spread': '114.89', 'groupId': 'OG002'}]}]}, {'title': 'Calculated at 3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '331', 'groupId': 'OG000'}, {'value': '329', 'groupId': 'OG001'}, {'value': '174', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '304.58', 'spread': '120.94', 'groupId': 'OG000'}, {'value': '301.97', 'spread': '117.57', 'groupId': 'OG001'}, {'value': '312.64', 'spread': '115.77', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline and 3 month follow-up', 'description': 'Genetic analyses of the microbiome of the fecal sample (microorganism DNA, not that of the person) will be performed. Reported here are the observed (total number of distinct taxa) and calculated (Chao1 = N + S2 / (2 D), where N is the number of observed OTUs (Operational Taxonomic Units), S is the number of singleton OTUs, and D is the number of doublet OTUs) number of species represented in the sample. Chao1 is a species richness calculator that accounts for rare species.', 'unitOfMeasure': 'species', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time-points.'}, {'type': 'OTHER_PRE_SPECIFIED', 'title': "Microbiome Alpha Diversity: Shannon Diversity Index (H')", 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '342', 'groupId': 'OG000'}, {'value': '344', 'groupId': 'OG001'}, {'value': '176', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '4.20', 'spread': '0.56', 'groupId': 'OG000'}, {'value': '4.19', 'spread': '0.54', 'groupId': 'OG001'}, {'value': '4.23', 'spread': '0.52', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '331', 'groupId': 'OG000'}, {'value': '329', 'groupId': 'OG001'}, {'value': '174', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '4.19', 'spread': '0.61', 'groupId': 'OG000'}, {'value': '4.20', 'spread': '0.51', 'groupId': 'OG001'}, {'value': '4.24', 'spread': '0.53', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline and 3 month follow-up', 'description': 'Genetic analyses of the microbiome of the fecal sample (microorganism DNA, not that of the person) will be performed. Shannon Diversity Index quantifies both the richness and the evenness of a community. It takes into account the number of taxa (richness) and their relative abundances (evenness). A higher Shannon index value indicates greater diversity, with both a high number of taxa and more even distribution of abundances among them. It is often used to assess the balance between species in a community. Typically ranges from 0-5 with higher numbers indicating increasing species diversity.', 'unitOfMeasure': "H' index", 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time-points.'}, {'type': 'OTHER_PRE_SPECIFIED', 'title': 'Microbiome Alpha Diversity: Inverse Simpson (1/D)', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '342', 'groupId': 'OG000'}, {'value': '344', 'groupId': 'OG001'}, {'value': '176', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '42.62', 'spread': '45.06', 'groupId': 'OG000'}, {'value': '42.54', 'spread': '45.04', 'groupId': 'OG001'}, {'value': '43.41', 'spread': '44.28', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '331', 'groupId': 'OG000'}, {'value': '329', 'groupId': 'OG001'}, {'value': '174', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '43.59', 'spread': '46.13', 'groupId': 'OG000'}, {'value': '42.21', 'spread': '44.66', 'groupId': 'OG001'}, {'value': '44.43', 'spread': '46.58', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline and 3 month follow-up', 'description': 'Genetic analyses of the microbiome of the fecal sample (microorganism DNA, not that of the person) will be performed. Simpson is the probability that any two microbes are the same species, ranging from 0-1. Inverse Simpson (1 / Simpson) considers both richness and evenness. It places greater weight on the more abundant taxa. A higher inverse Simpson index suggests a more even distribution of taxa, with fewer dominant species. The inverse Simpson index is sensitive to the presence of dominant species and may emphasize diversity loss when one or a few species dominate the community.', 'unitOfMeasure': '1/D index', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time-points.'}, {'type': 'OTHER_PRE_SPECIFIED', 'title': 'Microbiome Alpha Diversity: Pielou Evenness Index (J)', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '342', 'groupId': 'OG000'}, {'value': '344', 'groupId': 'OG001'}, {'value': '176', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '0.74', 'spread': '0.07', 'groupId': 'OG000'}, {'value': '0.74', 'spread': '0.06', 'groupId': 'OG001'}, {'value': '0.74', 'spread': '0.07', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '331', 'groupId': 'OG000'}, {'value': '329', 'groupId': 'OG001'}, {'value': '174', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '0.74', 'spread': '0.08', 'groupId': 'OG000'}, {'value': '0.75', 'spread': '0.06', 'groupId': 'OG001'}, {'value': '0.75', 'spread': '0.07', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline and 3 month follow-up', 'description': 'Genetic analyses of the microbiome of the fecal sample (microorganism DNA, not that of the person) will be performed. Pielou Evenness Index measures how evenly the individuals are distributed across the taxa in a sample. It is calculated by dividing the Shannon diversity index by the maximum possible value of the Shannon index (which occurs when all taxa are equally abundant). The Pielou index ranges from 0 (no evenness, where one species dominates) to 1 (perfect evenness, where all species are equally abundant).', 'unitOfMeasure': 'J index', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time-points.'}, {'type': 'OTHER_PRE_SPECIFIED', 'title': "Microbiome Alpha Diversity: Simpson's Dominance Index (D)", 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '342', 'groupId': 'OG000'}, {'value': '344', 'groupId': 'OG001'}, {'value': '176', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '0.04', 'spread': '0.03', 'groupId': 'OG000'}, {'value': '0.04', 'spread': '0.02', 'groupId': 'OG001'}, {'value': '0.03', 'spread': '0.02', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '331', 'groupId': 'OG000'}, {'value': '329', 'groupId': 'OG001'}, {'value': '174', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '0.04', 'spread': '0.05', 'groupId': 'OG000'}, {'value': '0.03', 'spread': '0.02', 'groupId': 'OG001'}, {'value': '0.03', 'spread': '0.02', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline and 3 month follow-up', 'description': "Genetic analyses of the microbiome of the fecal sample (microorganism DNA, not that of the person) will be performed. Simpson's Dominance Index measures the probability that two randomly selected individuals from a community belong to the same species (or taxon). It ranges from 0 to 1, where 0 indicates perfect diversity (no dominance of a single species) and values closer to 1 indicate that one or a few species dominate the community. A lower Simpson's dominance score suggests a more diverse community, while a higher score indicates a community dominated by a few taxa.", 'unitOfMeasure': 'D index', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time-points.'}, {'type': 'OTHER_PRE_SPECIFIED', 'title': 'Facial Behavior: Cheek Raise Score', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '387', 'groupId': 'OG000'}, {'value': '386', 'groupId': 'OG001'}, {'value': '189', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '11.92', 'spread': '15.40', 'groupId': 'OG000'}, {'value': '12.43', 'spread': '15.97', 'groupId': 'OG001'}, {'value': '10.06', 'spread': '12.86', 'groupId': 'OG002'}]}]}, {'title': 'Week 1', 'denoms': [{'units': 'Participants', 'counts': [{'value': '313', 'groupId': 'OG000'}, {'value': '308', 'groupId': 'OG001'}, {'value': '176', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '9.91', 'spread': '12.61', 'groupId': 'OG000'}, {'value': '10.05', 'spread': '13.39', 'groupId': 'OG001'}, {'value': '8.55', 'spread': '11.23', 'groupId': 'OG002'}]}]}, {'title': 'Week 2', 'denoms': [{'units': 'Participants', 'counts': [{'value': '287', 'groupId': 'OG000'}, {'value': '273', 'groupId': 'OG001'}, {'value': '162', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '9.77', 'spread': '12.25', 'groupId': 'OG000'}, {'value': '10.64', 'spread': '12.42', 'groupId': 'OG001'}, {'value': '7.43', 'spread': '10.60', 'groupId': 'OG002'}]}]}, {'title': 'Week 3', 'denoms': [{'units': 'Participants', 'counts': [{'value': '266', 'groupId': 'OG000'}, {'value': '274', 'groupId': 'OG001'}, {'value': '156', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '10.15', 'spread': '12.35', 'groupId': 'OG000'}, {'value': '10.28', 'spread': '13.73', 'groupId': 'OG001'}, {'value': '8.29', 'spread': '12.43', 'groupId': 'OG002'}]}]}, {'title': 'Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '294', 'groupId': 'OG000'}, {'value': '277', 'groupId': 'OG001'}, {'value': '166', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '10.40', 'spread': '12.27', 'groupId': 'OG000'}, {'value': '11.16', 'spread': '14.54', 'groupId': 'OG001'}, {'value': '8.58', 'spread': '10.12', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '284', 'groupId': 'OG000'}, {'value': '252', 'groupId': 'OG001'}, {'value': '154', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '11.57', 'spread': '13.99', 'groupId': 'OG000'}, {'value': '10.55', 'spread': '14.88', 'groupId': 'OG001'}, {'value': '8.60', 'spread': '12.84', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, week 1, week 2, week 3, week 4 (of intervention period), and 3 month follow-up', 'description': 'Participants provide video recordings of their face while responding to a prompt watching brief videos of positive valence (e.g., baby giggling). Data are reported in Action Unit 6 (AU6) of Facial Action Coding System (FACS). FACS is an anatomically-based system for describing facial movement, breaking facial expressions into individual muscle movements called Action Units (AUs). The scores indicate the intensity of cheek movement (0-100), higher movements indicate more intense movement.', 'unitOfMeasure': 'score on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time-points.'}, {'type': 'OTHER_PRE_SPECIFIED', 'title': 'Lure Discrimination Task (LDI)', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '444', 'groupId': 'OG000'}, {'value': '440', 'groupId': 'OG001'}, {'value': '220', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '0.44', 'spread': '0.20', 'groupId': 'OG000'}, {'value': '0.42', 'spread': '0.21', 'groupId': 'OG001'}, {'value': '0.41', 'spread': '0.21', 'groupId': 'OG002'}]}]}, {'title': 'Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '365', 'groupId': 'OG000'}, {'value': '351', 'groupId': 'OG001'}, {'value': '194', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '0.47', 'spread': '0.21', 'groupId': 'OG000'}, {'value': '0.45', 'spread': '0.22', 'groupId': 'OG001'}, {'value': '0.44', 'spread': '0.21', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '338', 'groupId': 'OG000'}, {'value': '329', 'groupId': 'OG001'}, {'value': '179', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '0.48', 'spread': '0.20', 'groupId': 'OG000'}, {'value': '0.46', 'spread': '0.22', 'groupId': 'OG001'}, {'value': '0.46', 'spread': '0.22', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, week 4 (of intervention period), and 3 month follow-up', 'description': 'Meditation training has the capacity to normalize the overgeneralized inflexible cognition endemic to depression, which is hypothesized to relate to alterations in the hippocampal-dependent process of pattern separation. The investigators will use a pattern separation task to evaluate hippocampal function. The Lure Discrimination Task (LDI) is the difference between the probability of giving a "Similar" response to the lure items (similar to target items) minus the probability of giving a "Similar" response to the foils (unrelated to target items). Larger differences indicate increased discrimination.', 'unitOfMeasure': 'Lure Discrimination Index', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time-points.'}, {'type': 'OTHER_PRE_SPECIFIED', 'title': 'Self-Referential Pronoun Use', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'Baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '402', 'groupId': 'OG000'}, {'value': '403', 'groupId': 'OG001'}, {'value': '208', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '8.75', 'spread': '3.20', 'groupId': 'OG000'}, {'value': '8.63', 'spread': '3.43', 'groupId': 'OG001'}, {'value': '8.47', 'spread': '3.46', 'groupId': 'OG002'}]}]}, {'title': 'Week 1', 'denoms': [{'units': 'Participants', 'counts': [{'value': '342', 'groupId': 'OG000'}, {'value': '334', 'groupId': 'OG001'}, {'value': '188', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '8.52', 'spread': '3.46', 'groupId': 'OG000'}, {'value': '8.42', 'spread': '3.48', 'groupId': 'OG001'}, {'value': '8.75', 'spread': '2.95', 'groupId': 'OG002'}]}]}, {'title': 'Week 2', 'denoms': [{'units': 'Participants', 'counts': [{'value': '321', 'groupId': 'OG000'}, {'value': '304', 'groupId': 'OG001'}, {'value': '171', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '8.48', 'spread': '3.35', 'groupId': 'OG000'}, {'value': '8.08', 'spread': '3.24', 'groupId': 'OG001'}, {'value': '8.23', 'spread': '3.42', 'groupId': 'OG002'}]}]}, {'title': 'Week 3', 'denoms': [{'units': 'Participants', 'counts': [{'value': '317', 'groupId': 'OG000'}, {'value': '304', 'groupId': 'OG001'}, {'value': '171', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '8.47', 'spread': '3.59', 'groupId': 'OG000'}, {'value': '8.57', 'spread': '3.18', 'groupId': 'OG001'}, {'value': '9.01', 'spread': '3.31', 'groupId': 'OG002'}]}]}, {'title': 'Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '336', 'groupId': 'OG000'}, {'value': '321', 'groupId': 'OG001'}, {'value': '190', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '8.07', 'spread': '3.28', 'groupId': 'OG000'}, {'value': '8.28', 'spread': '3.46', 'groupId': 'OG001'}, {'value': '8.81', 'spread': '3.41', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '312', 'groupId': 'OG000'}, {'value': '306', 'groupId': 'OG001'}, {'value': '167', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '8.44', 'spread': '3.48', 'groupId': 'OG000'}, {'value': '8.28', 'spread': '3.32', 'groupId': 'OG001'}, {'value': '8.67', 'spread': '3.35', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, week 1, week 2, week 3, week 4 (of intervention period), and 3 month follow-up', 'description': 'Participants provide recordings of their voice while responding to a prompt that asks to share information about their day. These recordings provide the opportunity to explore indicators of self-referent, inflexible, \\& over-generalized thinking within natural language. Reported here is the "I" self-referential word frequency.', 'unitOfMeasure': 'percent self referential words used', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time-points.'}, {'type': 'OTHER_PRE_SPECIFIED', 'title': 'Negative Affect Word Use: Negative Sentiment', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '402', 'groupId': 'OG000'}, {'value': '403', 'groupId': 'OG001'}, {'value': '208', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '2.94', 'spread': '1.95', 'groupId': 'OG000'}, {'value': '3.02', 'spread': '1.97', 'groupId': 'OG001'}, {'value': '2.87', 'spread': '2.03', 'groupId': 'OG002'}]}]}, {'title': 'Week 1', 'denoms': [{'units': 'Participants', 'counts': [{'value': '342', 'groupId': 'OG000'}, {'value': '334', 'groupId': 'OG001'}, {'value': '188', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '2.79', 'spread': '1.88', 'groupId': 'OG000'}, {'value': '2.90', 'spread': '2.05', 'groupId': 'OG001'}, {'value': '2.86', 'spread': '1.89', 'groupId': 'OG002'}]}]}, {'title': 'Week 2', 'denoms': [{'units': 'Participants', 'counts': [{'value': '321', 'groupId': 'OG000'}, {'value': '304', 'groupId': 'OG001'}, {'value': '171', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '2.76', 'spread': '1.84', 'groupId': 'OG000'}, {'value': '2.82', 'spread': '1.89', 'groupId': 'OG001'}, {'value': '2.72', 'spread': '1.90', 'groupId': 'OG002'}]}]}, {'title': 'Week 3', 'denoms': [{'units': 'Participants', 'counts': [{'value': '317', 'groupId': 'OG000'}, {'value': '304', 'groupId': 'OG001'}, {'value': '174', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '2.53', 'spread': '1.86', 'groupId': 'OG000'}, {'value': '2.76', 'spread': '1.87', 'groupId': 'OG001'}, {'value': '3.06', 'spread': '2.03', 'groupId': 'OG002'}]}]}, {'title': 'Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '336', 'groupId': 'OG000'}, {'value': '321', 'groupId': 'OG001'}, {'value': '190', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '2.51', 'spread': '1.81', 'groupId': 'OG000'}, {'value': '2.48', 'spread': '1.79', 'groupId': 'OG001'}, {'value': '2.77', 'spread': '2.07', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '312', 'groupId': 'OG000'}, {'value': '306', 'groupId': 'OG001'}, {'value': '167', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '2.72', 'spread': '1.98', 'groupId': 'OG000'}, {'value': '2.70', 'spread': '1.90', 'groupId': 'OG001'}, {'value': '2.89', 'spread': '2.10', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, week 1, week 2, week 3, week 4 (of intervention period), and 3 month follow-up', 'description': 'Participants provide recordings of their voice while responding to a prompt that asks to share information about their day. These recordings provide the opportunity to explore negative affect word use. Data are reported in percentage (0-100) where higher numbers indicate more intense negative sentiment.', 'unitOfMeasure': 'percent negative words used', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time points.'}, {'type': 'OTHER_PRE_SPECIFIED', 'title': 'Negative Affect Word Use: Positive Sentiment', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '402', 'groupId': 'OG000'}, {'value': '403', 'groupId': 'OG001'}, {'value': '208', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '3.12', 'spread': '2.12', 'groupId': 'OG000'}, {'value': '3.26', 'spread': '2.23', 'groupId': 'OG001'}, {'value': '3.32', 'spread': '2.19', 'groupId': 'OG002'}]}]}, {'title': 'Week 1', 'denoms': [{'units': 'Participants', 'counts': [{'value': '342', 'groupId': 'OG000'}, {'value': '334', 'groupId': 'OG001'}, {'value': '188', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '3.38', 'spread': '2.21', 'groupId': 'OG000'}, {'value': '3.21', 'spread': '2.18', 'groupId': 'OG001'}, {'value': '3.33', 'spread': '2.34', 'groupId': 'OG002'}]}]}, {'title': 'Week 2', 'denoms': [{'units': 'Participants', 'counts': [{'value': '321', 'groupId': 'OG000'}, {'value': '304', 'groupId': 'OG001'}, {'value': '171', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '3.29', 'spread': '2.02', 'groupId': 'OG000'}, {'value': '3.48', 'spread': '2.26', 'groupId': 'OG001'}, {'value': '3.41', 'spread': '2.19', 'groupId': 'OG002'}]}]}, {'title': 'Week 3', 'denoms': [{'units': 'Participants', 'counts': [{'value': '317', 'groupId': 'OG000'}, {'value': '304', 'groupId': 'OG001'}, {'value': '174', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '3.52', 'spread': '2.16', 'groupId': 'OG000'}, {'value': '3.39', 'spread': '2.10', 'groupId': 'OG001'}, {'value': '3.20', 'spread': '2.22', 'groupId': 'OG002'}]}]}, {'title': 'Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '336', 'groupId': 'OG000'}, {'value': '321', 'groupId': 'OG001'}, {'value': '190', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '3.68', 'spread': '2.32', 'groupId': 'OG000'}, {'value': '3.73', 'spread': '2.26', 'groupId': 'OG001'}, {'value': '3.47', 'spread': '2.34', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '312', 'groupId': 'OG000'}, {'value': '306', 'groupId': 'OG001'}, {'value': '167', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '3.45', 'spread': '2.27', 'groupId': 'OG000'}, {'value': '3.40', 'spread': '2.19', 'groupId': 'OG001'}, {'value': '3.55', 'spread': '2.59', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, week 1, week 2, week 3, week 4 (of intervention period), and 3 month follow-up', 'description': 'Participants provide recordings of their voice while responding to a prompt that asks to share information about their day. These recordings provide the opportunity to explore negative affect word use. Data are reported in percentage (0-100) where higher numbers indicate greater positive sentiment.', 'unitOfMeasure': 'percent positive sentiment', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time points.'}, {'type': 'OTHER_PRE_SPECIFIED', 'title': 'Treatment Expectancies', 'denoms': [{'units': 'Participants', 'counts': [{'value': '395', 'groupId': 'OG000'}, {'value': '387', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'categories': [{'measurements': [{'value': '35.07', 'spread': '11.28', 'groupId': 'OG000'}, {'value': '32.13', 'spread': '11.98', 'groupId': 'OG001'}]}]}], 'paramType': 'MEAN', 'timeFrame': '3-month follow-up', 'description': 'The Treatment Expectancies is a 6-item scale assessing how much participants believed the training program was helpful to them. Items assess how participants think (e.g., "At this point, how logical does the program offered to you seem?") and feel (e.g., "At this point, how much do you really feel that the program helped you to reduce your stress symptoms?"). Items are scored on either a 9-point Likert scale (e.g., 1 = "not at all logical" to 9 = "very logical") or on a percentage ("At the end of the program, how much improvement in your symptoms do you really feel occurred?", 0% to 100%). Higher scores reflect higher treatment expectancies.', 'unitOfMeasure': 'score on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'The usual care arm was not surveyed for this measure per protocol.'}, {'type': 'OTHER_PRE_SPECIFIED', 'title': 'Number of Participants With PHQ-8 Scores That Increased by 5 Points or More Compared to Baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'Overall (any time point)', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '78', 'groupId': 'OG000'}, {'value': '64', 'groupId': 'OG001'}, {'value': '44', 'groupId': 'OG002'}]}]}, {'title': 'Week 1', 'denoms': [{'units': 'Participants', 'counts': [{'value': '403', 'groupId': 'OG000'}, {'value': '407', 'groupId': 'OG001'}, {'value': '216', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '28', 'groupId': 'OG000'}, {'value': '27', 'groupId': 'OG001'}, {'value': '15', 'groupId': 'OG002'}]}]}, {'title': 'Week 2', 'denoms': [{'units': 'Participants', 'counts': [{'value': '376', 'groupId': 'OG000'}, {'value': '377', 'groupId': 'OG001'}, {'value': '204', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '27', 'groupId': 'OG000'}, {'value': '25', 'groupId': 'OG001'}, {'value': '11', 'groupId': 'OG002'}]}]}, {'title': 'Week 3', 'denoms': [{'units': 'Participants', 'counts': [{'value': '372', 'groupId': 'OG000'}, {'value': '366', 'groupId': 'OG001'}, {'value': '204', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '30', 'groupId': 'OG000'}, {'value': '21', 'groupId': 'OG001'}, {'value': '14', 'groupId': 'OG002'}]}]}, {'title': 'Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '395', 'groupId': 'OG000'}, {'value': '389', 'groupId': 'OG001'}, {'value': '218', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '24', 'groupId': 'OG000'}, {'value': '21', 'groupId': 'OG001'}, {'value': '14', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '374', 'groupId': 'OG000'}, {'value': '369', 'groupId': 'OG001'}, {'value': '204', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '20', 'groupId': 'OG000'}, {'value': '20', 'groupId': 'OG001'}, {'value': '17', 'groupId': 'OG002'}]}]}], 'paramType': 'COUNT_OF_PARTICIPANTS', 'timeFrame': 'Week 1, Week 2, Week 3, Week 4, 3-month follow-up', 'description': 'The PHQ-8 is an 8-item questionnaire where participants report how often in the past 2 weeks they were bothered by specific problems. Increase in scores indicates increase is depression symptoms.', 'unitOfMeasure': 'Participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time-points.'}, {'type': 'OTHER_PRE_SPECIFIED', 'title': 'Digital Working Alliance Inventory', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'Week 1', 'denoms': [{'units': 'Participants', 'counts': [{'value': '402', 'groupId': 'OG000'}, {'value': '407', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '32.04', 'spread': '6.35', 'groupId': 'OG000'}, {'value': '30.65', 'spread': '6.29', 'groupId': 'OG001'}]}]}, {'title': 'Week 2', 'denoms': [{'units': 'Participants', 'counts': [{'value': '376', 'groupId': 'OG000'}, {'value': '377', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '32.67', 'spread': '5.84', 'groupId': 'OG000'}, {'value': '30.89', 'spread': '6.89', 'groupId': 'OG001'}]}]}, {'title': 'Week 3', 'denoms': [{'units': 'Participants', 'counts': [{'value': '371', 'groupId': 'OG000'}, {'value': '366', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '33.37', 'spread': '6.55', 'groupId': 'OG000'}, {'value': '31.79', 'spread': '6.9', 'groupId': 'OG001'}]}]}, {'title': 'Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '395', 'groupId': 'OG000'}, {'value': '387', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '33.72', 'spread': '6.75', 'groupId': 'OG000'}, {'value': '32.25', 'spread': '7.27', 'groupId': 'OG001'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '367', 'groupId': 'OG000'}, {'value': '368', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '31.94', 'spread': '7.51', 'groupId': 'OG000'}, {'value': '30.89', 'spread': '7.53', 'groupId': 'OG001'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'week 1, week 2, week 3, week 4, and 3-month follow-up', 'description': 'The Digital Working Alliance Inventory is a 6-item scale where participants report their working alliance with the HMP app (e.g., "The HMP app supports me to overcome challenges"). It is scored on a 7-point Likert scale where 1 = "strongly disagree" to 7 = "strongly agree." Total scores range from 6 to 42 where higher scores indicate greater working alliance.', 'unitOfMeasure': 'score on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time points. The usual care arm was not surveyed for this measure per protocol.'}, {'type': 'OTHER_PRE_SPECIFIED', 'title': 'Inclusion of Nature in Self', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '232', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'baseline', 'denoms': [{'units': 'Participants', 'counts': [{'value': '461', 'groupId': 'OG000'}, {'value': '462', 'groupId': 'OG001'}, {'value': '231', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '4.06', 'spread': '1.70', 'groupId': 'OG000'}, {'value': '4.04', 'spread': '1.73', 'groupId': 'OG001'}, {'value': '3.89', 'spread': '1.72', 'groupId': 'OG002'}]}]}, {'title': 'Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '394', 'groupId': 'OG000'}, {'value': '385', 'groupId': 'OG001'}, {'value': '217', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '4.54', 'spread': '1.65', 'groupId': 'OG000'}, {'value': '4.26', 'spread': '1.74', 'groupId': 'OG001'}, {'value': '4.02', 'spread': '1.71', 'groupId': 'OG002'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '365', 'groupId': 'OG000'}, {'value': '366', 'groupId': 'OG001'}, {'value': '200', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '4.41', 'spread': '1.63', 'groupId': 'OG000'}, {'value': '4.18', 'spread': '1.73', 'groupId': 'OG001'}, {'value': '3.84', 'spread': '1.71', 'groupId': 'OG002'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, week 4 (of intervention period), and 3 month follow-up', 'description': 'The Inclusion of Nature in Self is a single item measure assessing the degree to which someone views nature as a part of their sense of self. Participants indicate which of a series of overlapping circles most closely resembles nature and their self. More overlapping circles indicate greater inclusion of nature in self.', 'unitOfMeasure': 'overlapping circles', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all-time points.'}, {'type': 'OTHER_PRE_SPECIFIED', 'title': 'Mindfulness Adherence Questionnaire', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'Week 1', 'denoms': [{'units': 'Participants', 'counts': [{'value': '401', 'groupId': 'OG000'}, {'value': '407', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '18.48', 'spread': '6.07', 'groupId': 'OG000'}, {'value': '18.93', 'spread': '6.27', 'groupId': 'OG001'}]}]}, {'title': 'Week 2', 'denoms': [{'units': 'Participants', 'counts': [{'value': '376', 'groupId': 'OG000'}, {'value': '377', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '20.61', 'spread': '6.15', 'groupId': 'OG000'}, {'value': '20.35', 'spread': '6.47', 'groupId': 'OG001'}]}]}, {'title': 'Week 3', 'denoms': [{'units': 'Participants', 'counts': [{'value': '370', 'groupId': 'OG000'}, {'value': '366', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '21.56', 'spread': '6.49', 'groupId': 'OG000'}, {'value': '21.09', 'spread': '6.48', 'groupId': 'OG001'}]}]}, {'title': 'Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '395', 'groupId': 'OG000'}, {'value': '387', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '22.22', 'spread': '6.5', 'groupId': 'OG000'}, {'value': '21.82', 'spread': '6.95', 'groupId': 'OG001'}]}]}, {'title': '3-month follow-up', 'denoms': [{'units': 'Participants', 'counts': [{'value': '367', 'groupId': 'OG000'}, {'value': '367', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '21.87', 'spread': '7.24', 'groupId': 'OG000'}, {'value': '21.96', 'spread': '7.05', 'groupId': 'OG001'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'week 1, week 2, week 3, week 4, and 3 month follow up', 'description': 'The Mindfulness Adherence Questionnaire informal practice items are 6-items assessing the application of mindfulness during daily life (e.g., "In your daily life, how much of the time were you practicing being gentle and compassionate toward yourself?"). It is scored on a 7-point Likert scale where 0 = "never" to 6 = "always." Total scores range from 0 to 42 where higher scores indicate greater informal mindfulness practice.', 'unitOfMeasure': 'score on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Some participants did not provide data at all time points. The usual care arm was not surveyed for this measure per protocol.'}, {'type': 'OTHER_PRE_SPECIFIED', 'title': 'Change in Pre- and Post-practice Positive Affect', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}, {'units': 'Surveys', 'counts': [{'value': '8667', 'groupId': 'OG000'}, {'value': '9269', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'Change from Before and After Intervention Week 1', 'denoms': [{'units': 'Participants', 'counts': [{'value': '386', 'groupId': 'OG000'}, {'value': '420', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}, {'units': 'Surveys', 'counts': [{'value': '2699', 'groupId': 'OG000'}, {'value': '3252', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '0.54', 'spread': '0.99', 'groupId': 'OG000'}, {'value': '0.35', 'spread': '0.90', 'groupId': 'OG001'}]}]}, {'title': 'Change from Before and After Intervention Week 2', 'denoms': [{'units': 'Participants', 'counts': [{'value': '383', 'groupId': 'OG000'}, {'value': '397', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}, {'units': 'Surveys', 'counts': [{'value': '2228', 'groupId': 'OG000'}, {'value': '2280', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '0.44', 'spread': '0.90', 'groupId': 'OG000'}, {'value': '0.33', 'spread': '0.83', 'groupId': 'OG001'}]}]}, {'title': 'Change from Before and After Intervention Week 3', 'denoms': [{'units': 'Participants', 'counts': [{'value': '381', 'groupId': 'OG000'}, {'value': '366', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}, {'units': 'Surveys', 'counts': [{'value': '2127', 'groupId': 'OG000'}, {'value': '2041', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '0.38', 'spread': '0.80', 'groupId': 'OG000'}, {'value': '0.28', 'spread': '0.76', 'groupId': 'OG001'}]}]}, {'title': 'Change from Before and After Intervention Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '339', 'groupId': 'OG000'}, {'value': '340', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}, {'units': 'Surveys', 'counts': [{'value': '1623', 'groupId': 'OG000'}, {'value': '1696', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '0.36', 'spread': '0.85', 'groupId': 'OG000'}, {'value': '0.24', 'spread': '0.78', 'groupId': 'OG001'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Before and after HMP activities week 1, week 2, week 2, and week 4', 'description': 'Two items assessing positive affect are scored on a 1- to 7-point Likert scale where 1 = not at all and 7 = very much. Data comes from multiple surveys.', 'unitOfMeasure': 'score on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'typeUnitsAnalyzed': 'Surveys', 'denomUnitsSelected': 'Surveys', 'populationDescription': 'The usual care arm was not surveyed for this measure per protocol.'}, {'type': 'OTHER_PRE_SPECIFIED', 'title': 'Change in Pre- and Post-practice Negative Affect', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}, {'units': 'Surveys', 'counts': [{'value': '8667', 'groupId': 'OG000'}, {'value': '9269', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'Change from Before and After Intervention Week 1', 'denoms': [{'units': 'Participants', 'counts': [{'value': '386', 'groupId': 'OG000'}, {'value': '420', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}, {'units': 'Surveys', 'counts': [{'value': '2699', 'groupId': 'OG000'}, {'value': '3252', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '-0.51', 'spread': '0.92', 'groupId': 'OG000'}, {'value': '-0.42', 'spread': '0.95', 'groupId': 'OG001'}]}]}, {'title': 'Change from Before and After Intervention Week 2', 'denoms': [{'units': 'Participants', 'counts': [{'value': '383', 'groupId': 'OG000'}, {'value': '397', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}, {'units': 'Surveys', 'counts': [{'value': '2228', 'groupId': 'OG000'}, {'value': '2280', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '-0.38', 'spread': '0.88', 'groupId': 'OG000'}, {'value': '-0.29', 'spread': '0.85', 'groupId': 'OG001'}]}]}, {'title': 'Change from Before and After Intervention Week 3', 'denoms': [{'units': 'Participants', 'counts': [{'value': '381', 'groupId': 'OG000'}, {'value': '366', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}, {'units': 'Surveys', 'counts': [{'value': '2117', 'groupId': 'OG000'}, {'value': '2041', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '-0.30', 'spread': '0.75', 'groupId': 'OG000'}, {'value': '-0.29', 'spread': '0.79', 'groupId': 'OG001'}]}]}, {'title': 'Change from Before and After Intervention Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '339', 'groupId': 'OG000'}, {'value': '340', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}, {'units': 'Surveys', 'counts': [{'value': '1623', 'groupId': 'OG000'}, {'value': '1696', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '-0.33', 'spread': '0.82', 'groupId': 'OG000'}, {'value': '-0.21', 'spread': '0.80', 'groupId': 'OG001'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Before and after HMP activities week 1, week 2, week 2, and week 4', 'description': 'Two items assessing negative affect are scored on a 1- to 7-point Likert scale where 1 = not at all and 7 = very much. Data comes from multiple surveys.', 'unitOfMeasure': 'score on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'typeUnitsAnalyzed': 'Surveys', 'denomUnitsSelected': 'Surveys', 'populationDescription': 'The usual care arm was not surveyed for this measure per protocol.'}, {'type': 'OTHER_PRE_SPECIFIED', 'title': 'Change in Post-practice Focus', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}, {'units': 'Surveys', 'counts': [{'value': '8663', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive full access to the 4-week HMP Foundations module. The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'OG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'classes': [{'title': 'Week 1', 'denoms': [{'units': 'Participants', 'counts': [{'value': '386', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}, {'units': 'Surveys', 'counts': [{'value': '2697', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '5.93', 'spread': '1.22', 'groupId': 'OG000'}]}]}, {'title': 'Week 2', 'denoms': [{'units': 'Participants', 'counts': [{'value': '383', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}, {'units': 'Surveys', 'counts': [{'value': '2228', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '6.08', 'spread': '1.14', 'groupId': 'OG000'}]}]}, {'title': 'Week 3', 'denoms': [{'units': 'Participants', 'counts': [{'value': '381', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}, {'units': 'Surveys', 'counts': [{'value': '2116', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '6.08', 'spread': '1.23', 'groupId': 'OG000'}]}]}, {'title': 'Week 4', 'denoms': [{'units': 'Participants', 'counts': [{'value': '339', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}, {'units': 'Surveys', 'counts': [{'value': '1622', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}], 'categories': [{'measurements': [{'value': '6.21', 'spread': '1.06', 'groupId': 'OG000'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Before and after HMP activities week 1, week 2, week 2, and week 4', 'description': 'A single item assessing focus during HMP activities is scored on a 1- to 7-point Likert scale where 1 = not at all and 7 = most of the time. Data comes from multiple surveys.', 'unitOfMeasure': 'score on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'typeUnitsAnalyzed': 'Surveys', 'denomUnitsSelected': 'Surveys', 'populationDescription': 'Data collected only from HMP arm per protocol.'}]}, 'participantFlowModule': {'groups': [{'id': 'FG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive access to the 4-week HMP Foundations module. The HMP app is a meditation-based smartphone app designed to promote and protect psychological well-being through sustainable skills training. The program is grounded in constituents of psychological well-being identified in empirical literature. HMP provides core content, with instruction administered through a curriculum of guided practices. HMP is based on research on eudaimonic well-being (e.g., environmental mastery, purpose) and brain-based skills that underlie these qualities (e.g., regulation of attention, mental flexibility). The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'FG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'FG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'periods': [{'title': 'Overall Study', 'milestones': [{'type': 'STARTED', 'achievements': [{'groupId': 'FG000', 'numSubjects': '462'}, {'groupId': 'FG001', 'numSubjects': '463'}, {'groupId': 'FG002', 'numSubjects': '232'}]}, {'type': 'COMPLETED', 'achievements': [{'groupId': 'FG000', 'numSubjects': '459'}, {'groupId': 'FG001', 'numSubjects': '461'}, {'groupId': 'FG002', 'numSubjects': '232'}]}, {'type': 'NOT COMPLETED', 'achievements': [{'groupId': 'FG000', 'numSubjects': '3'}, {'groupId': 'FG001', 'numSubjects': '2'}, {'groupId': 'FG002', 'numSubjects': '0'}]}], 'dropWithdraws': [{'type': 'Withdrawal by Subject', 'reasons': [{'groupId': 'FG000', 'numSubjects': '3'}, {'groupId': 'FG001', 'numSubjects': '2'}, {'groupId': 'FG002', 'numSubjects': '0'}]}]}]}, 'baselineCharacteristicsModule': {'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'BG000'}, {'value': '463', 'groupId': 'BG001'}, {'value': '232', 'groupId': 'BG002'}, {'value': '1157', 'groupId': 'BG003'}]}], 'groups': [{'id': 'BG000', 'title': 'Healthy Minds Program (HMP) App', 'description': 'Participants will receive access to the 4-week HMP Foundations module. The HMP app is a meditation-based smartphone app designed to promote and protect psychological well-being through sustainable skills training. The program is grounded in constituents of psychological well-being identified in empirical literature. HMP provides core content, with instruction administered through a curriculum of guided practices. HMP is based on research on eudaimonic well-being (e.g., environmental mastery, purpose) and brain-based skills that underlie these qualities (e.g., regulation of attention, mental flexibility). The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'BG001', 'title': 'Psychoeducation App', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.\n\nHealthy Minds Program: HMP is a 4-week mobile health (mHealth) meditation training program.'}, {'id': 'BG002', 'title': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}, {'id': 'BG003', 'title': 'Total', 'description': 'Total of all reporting groups'}], 'measures': [{'title': 'Age, Continuous', 'classes': [{'categories': [{'measurements': [{'value': '38.34', 'spread': '11.84', 'groupId': 'BG000'}, {'value': '39.02', 'spread': '12.18', 'groupId': 'BG001'}, {'value': '38.72', 'spread': '12.64', 'groupId': 'BG002'}, {'value': '38.69', 'spread': '12.13', 'groupId': 'BG003'}]}]}], 'paramType': 'MEAN', 'unitOfMeasure': 'years', 'dispersionType': 'STANDARD_DEVIATION'}, {'title': 'Sex/Gender, Customized', 'classes': [{'categories': [{'title': 'Man', 'measurements': [{'value': '93', 'groupId': 'BG000'}, {'value': '103', 'groupId': 'BG001'}, {'value': '49', 'groupId': 'BG002'}, {'value': '245', 'groupId': 'BG003'}]}, {'title': 'Woman', 'measurements': [{'value': '355', 'groupId': 'BG000'}, {'value': '342', 'groupId': 'BG001'}, {'value': '173', 'groupId': 'BG002'}, {'value': '870', 'groupId': 'BG003'}]}, {'title': 'Other', 'measurements': [{'value': '3', 'groupId': 'BG000'}, {'value': '7', 'groupId': 'BG001'}, {'value': '2', 'groupId': 'BG002'}, {'value': '12', 'groupId': 'BG003'}]}, {'title': 'Unknown or Not Reported', 'measurements': [{'value': '11', 'groupId': 'BG000'}, {'value': '11', 'groupId': 'BG001'}, {'value': '8', 'groupId': 'BG002'}, {'value': '30', 'groupId': 'BG003'}]}]}], 'paramType': 'COUNT_OF_PARTICIPANTS', 'unitOfMeasure': 'Participants'}, {'title': 'Ethnicity (NIH/OMB)', 'classes': [{'categories': [{'title': 'Hispanic or Latino', 'measurements': [{'value': '48', 'groupId': 'BG000'}, {'value': '40', 'groupId': 'BG001'}, {'value': '24', 'groupId': 'BG002'}, {'value': '112', 'groupId': 'BG003'}]}, {'title': 'Not Hispanic or Latino', 'measurements': [{'value': '400', 'groupId': 'BG000'}, {'value': '406', 'groupId': 'BG001'}, {'value': '198', 'groupId': 'BG002'}, {'value': '1004', 'groupId': 'BG003'}]}, {'title': 'Unknown or Not Reported', 'measurements': [{'value': '14', 'groupId': 'BG000'}, {'value': '17', 'groupId': 'BG001'}, {'value': '10', 'groupId': 'BG002'}, {'value': '41', 'groupId': 'BG003'}]}]}], 'paramType': 'COUNT_OF_PARTICIPANTS', 'unitOfMeasure': 'Participants'}, {'title': 'Race (NIH/OMB)', 'classes': [{'categories': [{'title': 'American Indian or Alaska Native', 'measurements': [{'value': '2', 'groupId': 'BG000'}, {'value': '5', 'groupId': 'BG001'}, {'value': '1', 'groupId': 'BG002'}, {'value': '8', 'groupId': 'BG003'}]}, {'title': 'Asian', 'measurements': [{'value': '26', 'groupId': 'BG000'}, {'value': '24', 'groupId': 'BG001'}, {'value': '12', 'groupId': 'BG002'}, {'value': '62', 'groupId': 'BG003'}]}, {'title': 'Native Hawaiian or Other Pacific Islander', 'measurements': [{'value': '0', 'groupId': 'BG000'}, {'value': '1', 'groupId': 'BG001'}, {'value': '1', 'groupId': 'BG002'}, {'value': '2', 'groupId': 'BG003'}]}, {'title': 'Black or African American', 'measurements': [{'value': '36', 'groupId': 'BG000'}, {'value': '46', 'groupId': 'BG001'}, {'value': '21', 'groupId': 'BG002'}, {'value': '103', 'groupId': 'BG003'}]}, {'title': 'White', 'measurements': [{'value': '341', 'groupId': 'BG000'}, {'value': '357', 'groupId': 'BG001'}, {'value': '176', 'groupId': 'BG002'}, {'value': '874', 'groupId': 'BG003'}]}, {'title': 'More than one race', 'measurements': [{'value': '45', 'groupId': 'BG000'}, {'value': '25', 'groupId': 'BG001'}, {'value': '12', 'groupId': 'BG002'}, {'value': '82', 'groupId': 'BG003'}]}, {'title': 'Unknown or Not Reported', 'measurements': [{'value': '12', 'groupId': 'BG000'}, {'value': '5', 'groupId': 'BG001'}, {'value': '9', 'groupId': 'BG002'}, {'value': '26', 'groupId': 'BG003'}]}]}], 'paramType': 'COUNT_OF_PARTICIPANTS', 'unitOfMeasure': 'Participants'}, {'title': 'Region of Enrollment', 'classes': [{'title': 'United States', 'categories': [{'measurements': [{'value': '462', 'groupId': 'BG000'}, {'value': '463', 'groupId': 'BG001'}, {'value': '232', 'groupId': 'BG002'}, {'value': '1157', 'groupId': 'BG003'}]}]}], 'paramType': 'NUMBER', 'unitOfMeasure': 'participants'}]}}, 'documentSection': {'largeDocumentModule': {'largeDocs': [{'date': '2025-01-16', 'size': 839867, 'label': 'Study Protocol and Statistical Analysis Plan', 'hasIcf': False, 'hasSap': True, 'filename': 'Prot_SAP_001.pdf', 'typeAbbrev': 'Prot_SAP', 'uploadDate': '2025-04-08T14:32', 'hasProtocol': True}, {'date': '2023-12-20', 'size': 250377, 'label': 'Informed Consent Form', 'hasIcf': True, 'hasSap': False, 'filename': 'ICF_000.pdf', 'typeAbbrev': 'ICF', 'uploadDate': '2024-07-22T16:32', 'hasProtocol': False}]}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'DOUBLE', 'whoMasked': ['PARTICIPANT', 'OUTCOMES_ASSESSOR']}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'PARALLEL', 'interventionModelDescription': 'The groups will be randomized to one of three groups in a 2:2:1 ratio.'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 1157}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2022-03-24', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2025-08', 'completionDateStruct': {'date': '2024-07-15', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2025-08-19', 'studyFirstSubmitDate': '2021-12-21', 'resultsFirstSubmitDate': '2025-06-02', 'studyFirstSubmitQcDate': '2021-12-21', 'lastUpdatePostDateStruct': {'date': '2025-09-09', 'type': 'ESTIMATED'}, 'resultsFirstSubmitQcDate': '2025-07-15', 'studyFirstPostDateStruct': {'date': '2022-01-11', 'type': 'ACTUAL'}, 'resultsFirstPostDateStruct': {'date': '2025-08-01', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2024-07-15', 'type': 'ACTUAL'}}, 'outcomesModule': {'otherOutcomes': [{'measure': 'Inflammatory Biomarkers: C-reactive Protein (CRP)', 'timeFrame': 'Baseline and 3 month follow-up', 'description': 'Dried blood spot samples will be used to measure two inflammatory cytokines (C-reactive protein (CRP) and interleukin-6 (IL-6)). Additionally mRNA assays will be used to detect and quantify inflammatory gene expression detect and monitor cellular immune responses. Analyses will focus on transcripts from \\~200 genes known to be involved in the regulation of inflammation, and will consider key transcripts (e.g., IL-1beta, TNF-alpha) as well as summary measures reflecting the activity of transcriptional networks that coordinate inflammation (NF-kB, AP-1).'}, {'measure': 'Inflammatory Biomarkers: TNF-Alpha, IL-6, Il-10', 'timeFrame': 'Baseline and 3 month follow-up', 'description': 'Dried blood spot samples will be used to measure two inflammatory cytokines (C-reactive protein (CRP) and interleukin-6 (IL-6)). Additionally mRNA assays will be used to detect and quantify inflammatory gene expression detect and monitor cellular immune responses. Analyses will focus on transcripts from \\~200 genes known to be involved in the regulation of inflammation, and will consider key transcripts (e.g., IL-1beta, TNF-alpha) as well as summary measures reflecting the activity of transcriptional networks that coordinate inflammation (NF-kB, AP-1).'}, {'measure': 'Microbiome Alpha Diversity: Species Richness', 'timeFrame': 'Baseline and 3 month follow-up', 'description': 'Genetic analyses of the microbiome of the fecal sample (microorganism DNA, not that of the person) will be performed. Reported here are the observed (total number of distinct taxa) and calculated (Chao1 = N + S2 / (2 D), where N is the number of observed OTUs (Operational Taxonomic Units), S is the number of singleton OTUs, and D is the number of doublet OTUs) number of species represented in the sample. Chao1 is a species richness calculator that accounts for rare species.'}, {'measure': "Microbiome Alpha Diversity: Shannon Diversity Index (H')", 'timeFrame': 'Baseline and 3 month follow-up', 'description': 'Genetic analyses of the microbiome of the fecal sample (microorganism DNA, not that of the person) will be performed. Shannon Diversity Index quantifies both the richness and the evenness of a community. It takes into account the number of taxa (richness) and their relative abundances (evenness). A higher Shannon index value indicates greater diversity, with both a high number of taxa and more even distribution of abundances among them. It is often used to assess the balance between species in a community. Typically ranges from 0-5 with higher numbers indicating increasing species diversity.'}, {'measure': 'Microbiome Alpha Diversity: Inverse Simpson (1/D)', 'timeFrame': 'Baseline and 3 month follow-up', 'description': 'Genetic analyses of the microbiome of the fecal sample (microorganism DNA, not that of the person) will be performed. Simpson is the probability that any two microbes are the same species, ranging from 0-1. Inverse Simpson (1 / Simpson) considers both richness and evenness. It places greater weight on the more abundant taxa. A higher inverse Simpson index suggests a more even distribution of taxa, with fewer dominant species. The inverse Simpson index is sensitive to the presence of dominant species and may emphasize diversity loss when one or a few species dominate the community.'}, {'measure': 'Microbiome Alpha Diversity: Pielou Evenness Index (J)', 'timeFrame': 'Baseline and 3 month follow-up', 'description': 'Genetic analyses of the microbiome of the fecal sample (microorganism DNA, not that of the person) will be performed. Pielou Evenness Index measures how evenly the individuals are distributed across the taxa in a sample. It is calculated by dividing the Shannon diversity index by the maximum possible value of the Shannon index (which occurs when all taxa are equally abundant). The Pielou index ranges from 0 (no evenness, where one species dominates) to 1 (perfect evenness, where all species are equally abundant).'}, {'measure': "Microbiome Alpha Diversity: Simpson's Dominance Index (D)", 'timeFrame': 'Baseline and 3 month follow-up', 'description': "Genetic analyses of the microbiome of the fecal sample (microorganism DNA, not that of the person) will be performed. Simpson's Dominance Index measures the probability that two randomly selected individuals from a community belong to the same species (or taxon). It ranges from 0 to 1, where 0 indicates perfect diversity (no dominance of a single species) and values closer to 1 indicate that one or a few species dominate the community. A lower Simpson's dominance score suggests a more diverse community, while a higher score indicates a community dominated by a few taxa."}, {'measure': 'Facial Behavior: Cheek Raise Score', 'timeFrame': 'Baseline, week 1, week 2, week 3, week 4 (of intervention period), and 3 month follow-up', 'description': 'Participants provide video recordings of their face while responding to a prompt watching brief videos of positive valence (e.g., baby giggling). Data are reported in Action Unit 6 (AU6) of Facial Action Coding System (FACS). FACS is an anatomically-based system for describing facial movement, breaking facial expressions into individual muscle movements called Action Units (AUs). The scores indicate the intensity of cheek movement (0-100), higher movements indicate more intense movement.'}, {'measure': 'Lure Discrimination Task (LDI)', 'timeFrame': 'Baseline, week 4 (of intervention period), and 3 month follow-up', 'description': 'Meditation training has the capacity to normalize the overgeneralized inflexible cognition endemic to depression, which is hypothesized to relate to alterations in the hippocampal-dependent process of pattern separation. The investigators will use a pattern separation task to evaluate hippocampal function. The Lure Discrimination Task (LDI) is the difference between the probability of giving a "Similar" response to the lure items (similar to target items) minus the probability of giving a "Similar" response to the foils (unrelated to target items). Larger differences indicate increased discrimination.'}, {'measure': 'Self-Referential Pronoun Use', 'timeFrame': 'Baseline, week 1, week 2, week 3, week 4 (of intervention period), and 3 month follow-up', 'description': 'Participants provide recordings of their voice while responding to a prompt that asks to share information about their day. These recordings provide the opportunity to explore indicators of self-referent, inflexible, \\& over-generalized thinking within natural language. Reported here is the "I" self-referential word frequency.'}, {'measure': 'Negative Affect Word Use: Negative Sentiment', 'timeFrame': 'Baseline, week 1, week 2, week 3, week 4 (of intervention period), and 3 month follow-up', 'description': 'Participants provide recordings of their voice while responding to a prompt that asks to share information about their day. These recordings provide the opportunity to explore negative affect word use. Data are reported in percentage (0-100) where higher numbers indicate more intense negative sentiment.'}, {'measure': 'Negative Affect Word Use: Positive Sentiment', 'timeFrame': 'Baseline, week 1, week 2, week 3, week 4 (of intervention period), and 3 month follow-up', 'description': 'Participants provide recordings of their voice while responding to a prompt that asks to share information about their day. These recordings provide the opportunity to explore negative affect word use. Data are reported in percentage (0-100) where higher numbers indicate greater positive sentiment.'}, {'measure': 'Treatment Expectancies', 'timeFrame': '3-month follow-up', 'description': 'The Treatment Expectancies is a 6-item scale assessing how much participants believed the training program was helpful to them. Items assess how participants think (e.g., "At this point, how logical does the program offered to you seem?") and feel (e.g., "At this point, how much do you really feel that the program helped you to reduce your stress symptoms?"). Items are scored on either a 9-point Likert scale (e.g., 1 = "not at all logical" to 9 = "very logical") or on a percentage ("At the end of the program, how much improvement in your symptoms do you really feel occurred?", 0% to 100%). Higher scores reflect higher treatment expectancies.'}, {'measure': 'Number of Participants With PHQ-8 Scores That Increased by 5 Points or More Compared to Baseline', 'timeFrame': 'Week 1, Week 2, Week 3, Week 4, 3-month follow-up', 'description': 'The PHQ-8 is an 8-item questionnaire where participants report how often in the past 2 weeks they were bothered by specific problems. Increase in scores indicates increase is depression symptoms.'}, {'measure': 'Digital Working Alliance Inventory', 'timeFrame': 'week 1, week 2, week 3, week 4, and 3-month follow-up', 'description': 'The Digital Working Alliance Inventory is a 6-item scale where participants report their working alliance with the HMP app (e.g., "The HMP app supports me to overcome challenges"). It is scored on a 7-point Likert scale where 1 = "strongly disagree" to 7 = "strongly agree." Total scores range from 6 to 42 where higher scores indicate greater working alliance.'}, {'measure': 'Inclusion of Nature in Self', 'timeFrame': 'Baseline, week 4 (of intervention period), and 3 month follow-up', 'description': 'The Inclusion of Nature in Self is a single item measure assessing the degree to which someone views nature as a part of their sense of self. Participants indicate which of a series of overlapping circles most closely resembles nature and their self. More overlapping circles indicate greater inclusion of nature in self.'}, {'measure': 'Mindfulness Adherence Questionnaire', 'timeFrame': 'week 1, week 2, week 3, week 4, and 3 month follow up', 'description': 'The Mindfulness Adherence Questionnaire informal practice items are 6-items assessing the application of mindfulness during daily life (e.g., "In your daily life, how much of the time were you practicing being gentle and compassionate toward yourself?"). It is scored on a 7-point Likert scale where 0 = "never" to 6 = "always." Total scores range from 0 to 42 where higher scores indicate greater informal mindfulness practice.'}, {'measure': 'Change in Pre- and Post-practice Positive Affect', 'timeFrame': 'Before and after HMP activities week 1, week 2, week 2, and week 4', 'description': 'Two items assessing positive affect are scored on a 1- to 7-point Likert scale where 1 = not at all and 7 = very much. Data comes from multiple surveys.'}, {'measure': 'Change in Pre- and Post-practice Negative Affect', 'timeFrame': 'Before and after HMP activities week 1, week 2, week 2, and week 4', 'description': 'Two items assessing negative affect are scored on a 1- to 7-point Likert scale where 1 = not at all and 7 = very much. Data comes from multiple surveys.'}, {'measure': 'Change in Post-practice Focus', 'timeFrame': 'Before and after HMP activities week 1, week 2, week 2, and week 4', 'description': 'A single item assessing focus during HMP activities is scored on a 1- to 7-point Likert scale where 1 = not at all and 7 = most of the time. Data comes from multiple surveys.'}], 'primaryOutcomes': [{'measure': 'Depression Symptoms Measured by Patient Health Questionnaire - 8 (PHQ-8) Score', 'timeFrame': 'Baseline, week 1, week 2, week 3, week 4 (of intervention period), and 3 month follow-up', 'description': 'The PHQ-8 is an 8-item questionnaire where participants report how often in the past 2 weeks they were bothered by specific problems. It is scored on a 4-point Likert scale where 0 = not at all to 3 = nearly every day. The total possible range of scores is 0-24 where higher scores indicate more depressive symptoms.'}], 'secondaryOutcomes': [{'measure': 'Anxiety Symptoms Measured by Generalized Anxiety Disorder - 7 (GAD-7) Score', 'timeFrame': 'Baseline, week 1, week 2, week 3, week 4 (of intervention period), and 3 month follow-up', 'description': 'The GAD-7 is a 7-item questionnaire where participants report how often in the past 2 weeks they were bothered by specific problems. It is scored on a 4-point Likert scale where 0 = not at all to 3 = nearly every day. The total possible range of scores is 0-21 where higher scores indicate more anxious symptoms.'}, {'measure': 'Sleep Disturbance Measured by Patient-Reported Outcomes Measurement Information System (PROMIS) Sleep Disturbance Score', 'timeFrame': 'Baseline, week 1, week 2, week 3, week 4 (of intervention period), and 3 month follow-up', 'description': 'The PROMIS Sleep Disturbance scale is a computer-adaptive measure where participants report how often in the past 7 days they had various sleep-related experiences (e.g., "my sleep was restful"). It is scored on a 5-point Likert scale where 1 = not at all to 5 = very much. It provides total scores as T-scores (mean = 50, standard deviation (SD) = 10) where higher scores indicate more sleep disturbance.'}, {'measure': 'Flourishing Measured by the Flourishing Index Score', 'timeFrame': 'Baseline, week 1, week 2, week 3, week 4 (of intervention period), and 3 month follow-up', 'description': 'The Flourishing Index is a 10-item questionnaire where participants report their general level of flourishing (e.g., well-being, health, etc.). It is scored on a 0 to 10-point scale, with anchors varying across items. The total score ranges from 0 to 100 with higher scores indicating higher flourishing.'}, {'measure': 'Awareness Measured by Five Facet Mindfulness Questionnaire Acting With Awareness Subscale Score', 'timeFrame': 'Baseline, week 1, week 2, week 3, week 4 (of intervention period), and 3 month follow-up', 'description': 'The Five Facet Mindfulness Questionnaire Acting with Awareness Subscale is a 8-item subscale where participants report on their general ability to focus. It is scored on a 5-point Likert scale where 1 = never or very rarely true to 5 = very often or always true. The total possible range of scores is 8-40 where higher scores indicate a greater ability to focus.'}, {'measure': 'Connection Measured by NIH Toolbox Loneliness Score', 'timeFrame': 'Baseline, week 1, week 2, week 3, week 4 (of intervention period), and 3 month follow-up', 'description': 'The NIH Toolbox Loneliness is a 5-item questionnaire where participants report how often in the past week they have felt loneliness. It is scored on a 5-point Likert scale where 1 = never to 5 = always. The total possible range of scores is 5-25 where higher scores indicate a greater sense of loneliness.'}, {'measure': 'Decentering Measured by Decentering Subscale of Experiencing Questionnaire Scale Score', 'timeFrame': 'Baseline, week 1, week 2, week 3, week 4 (of intervention period), and 3 month follow-up', 'description': 'The Decentering subscale of the Experience Questionnaire is an 11-item questionnaire where participants report on their ability to decenter from their experience. It is scored on a 5-point Likert scale where 1 = never to 5 = all the time. The total possible range of scores is 11-55 where higher scores indicate a greater ability to decenter from experience.'}, {'measure': 'Meaning in Life Measured by NIH Toolbox Meaning and Purpose Score', 'timeFrame': 'Baseline, week 1, week 2, week 3, week 4 (of intervention period), and 3 month follow-up', 'description': 'The PROMIS / NIH Toolbox Meaning and Purpose is a computer-adaptive measure where participants report how much meaning and purpose they experience in life (e.g., "I understand my life\'s meaning"). It is scored on a 5-point Likert scale where 1 = strongly disagree to 5 = strongly agree. It provides total scores as T-scores (mean = 50, SD = 10) where higher scores indicate more meaning and purpose in life.'}, {'measure': 'Pain Intensity Measured by PROMIS Pain Intensity Score', 'timeFrame': 'Baseline, week 4 (of intervention period), and 3 month follow-up', 'description': 'The single-item PROMIS Pain Intensity scale is a 1-item scale where participants report on their pain intensity in the past 7 days. It is scored on an 11-point Likert-scale where 0 = no pain and 10 = worst pain imaginable. Scores range from 0 to 10, with higher scores indicating higher pain intensity'}, {'measure': 'Pain Interference Measured by PROMIS Pain Inference Scale Score', 'timeFrame': 'Baseline, week 4 (of intervention period), and 3 month follow-up', 'description': 'The PROMIS Pain Interference scale is a computer-adaptive measure where participants report how often in the past 7 days they had pain-related interference in their life (e.g., "how much did pain interfere with your enjoyment of life"). It is scored on a 5-point Likert scale where 1 = not at all to 5 = very much. It provides total scores as T-scores (mean = 50, SD = 10) where higher scores indicate more pain interference.'}, {'measure': 'Nonjudgment Measured by Five Facet Mindfulness Questionnaire Nonjudgment Subscale Score', 'timeFrame': 'Baseline, week 1, week 2, week 3, week 4 (of intervention period), and 3 month follow-up', 'description': 'The Five Facet Mindfulness Questionnaire Nonjudgment Subscale is a 8-item subscale where participants report on their nonjudgment of experience in daily life. It is scored on a 5-point Likert scale where 1 = never or very rarely true to 5 = very often or always true. The total possible range of scores is 8-40 where higher scores indicate a greater nonjudgment of experience.'}, {'measure': 'Climate Change Anxiety Scale', 'timeFrame': 'Baseline, week 4, and 3 month follow up', 'description': 'The Climate Change Anxiety Scale is a 13-item scale where participants report their anxiety regarding climate change (e.g., "I have nightmares about climate change"). It is scored on a 5-point Likert scale where 1 = "never" to 5 = "almost always." Total scores range from 13 to 65 where higher scores indicate greater climate change anxiety.'}, {'measure': 'Wellbeing Growth Mindset', 'timeFrame': 'Baseline, week 4, and 3 month follow up', 'description': 'The Wellbeing Growth Mindset scale is a 3-item scale where participants report whether they believe wellbeing is malleable (e.g., "Your well-being is something about you that you can\'t change very much."). It is scored on a 6-point Likert scale where 1 = "strongly disagree" to 6 = "strongly agree." Total scores range from 3 to 18 where higher scores indicate greater wellbeing growth mindset.'}, {'measure': 'Healthy Minds Index (HM Index) - Awareness', 'timeFrame': 'Baseline, week 4, and 3 month follow up', 'description': 'The HM Index is a 17-item questionnaire assessing qualities trained in the HMP app (awareness, connection, insight, purpose). It is scored on a 0- to 4-point Likert scale where 0 = a low amount (e.g., never, not at all, none of the time) and 4 = a higher amount (e.g., always, to the highest degree, all of the time) of a particular quality. Total scores for the Awareness subscale is 0 to 16 where higher scores indicate more awareness.'}, {'measure': 'Healthy Minds Index (HM Index) - Connection', 'timeFrame': 'Baseline, week 4, and 3 month follow up', 'description': 'The HM Index is a 17-item questionnaire assessing qualities trained in the HMP app (awareness, connection, insight, purpose). It is scored on a 0- to 4-point Likert scale where 0 = a low amount (e.g., never, not at all, none of the time) and 4 = a higher amount (e.g., always, to the highest degree, all of the time) of a particular quality. Total scores for the Connection subscale range from 0 to 24, where higher scores indicate more connection.'}, {'measure': 'Healthy Minds Index (HM Index) - Insight', 'timeFrame': 'Baseline, week 4, and 3 month follow up', 'description': 'The HM Index is a 17-item questionnaire assessing qualities trained in the HMP app (awareness, connection, insight, purpose). It is scored on a 0- to 4-point Likert scale where 0 = a low amount (e.g., never, not at all, none of the time) and 4 = a higher amount (e.g., always, to the highest degree, all of the time) of a particular quality. Total scores for the Insight subscale range from 0 to 12, where higher scores indicate more insight.'}, {'measure': 'Healthy Minds Index (HM Index) - Purpose', 'timeFrame': 'Baseline, week 4, and 3 month follow up', 'description': 'The HM Index is a 17-item questionnaire assessing qualities trained in the HMP app (awareness, connection, insight, purpose). It is scored on a 0- to 4-point Likert scale where 0 = a low amount (e.g., never, not at all, none of the time) and 4 = a higher amount (e.g., always, to the highest degree, all of the time) of a particular quality. Total scores for the Purpose subscale range from 0 to 16, where higher scores indicate more purpose.'}, {'measure': 'Life Orientation Test - Revised', 'timeFrame': 'Baseline, week 4, and 3 month follow up', 'description': 'The Life Orientation Test - Revised is a 6-item scale where participants report their level of optimism (e.g., "In uncertain times, I usually expect the best"). It is scored on a 5-point Likert scale where 0 = "strongly disagree" to 4 = "strongly agree." Total scores range from 0 to 24 where higher scores indicate greater optimism.'}, {'measure': 'Perceived Stress Scale', 'timeFrame': 'Baseline, week 4, and 3 month follow up', 'description': 'The Perceived Stress Scale is a 10-item scale where participants report their level of perceived stress (e.g., "In the last month, how often have you felt nervous and \'stressed\'?"). It is scored on a 5-point Likert scale where 0 = "never" to 4 = "very often." Total scores range from 0 to 40 where higher scores indicate greater perceived stress.'}, {'measure': 'Perseverative Thinking Questionnaire', 'timeFrame': 'Baseline, week 4, and 3 month follow up', 'description': 'The Perseverative Thinking Questionnaire is a 15-item scale where participants report their level of repetitive negative thinking (e.g., "My thoughts repeat themselves"). It is scored on a 5-point Likert scale where 0 = "never" to 4 = "almost always." Total scores range from 0 to 60 where higher scores indicate greater perseverative thinking.'}, {'measure': 'Satisfaction With Life Scale', 'timeFrame': 'Baseline, week 4, and 3 month follow up', 'description': 'The Satisfaction with Life Scale is a 5-item scale where participants report their level of satisfaction with life (e.g., "In most ways my life is close to ideal"). It is scored on a 7-point Likert scale where 1 = "strongly disagree" to 7 = "strongly agree." Total scores range from 5 to 35 where higher scores indicate greater satisfaction with life.'}, {'measure': 'Subjective Happiness Scale', 'timeFrame': 'Baseline, week 4, and 3 month follow up', 'description': 'The Subjective Happiness Scale is a 4-item scale where participants report their level of subjective happiness (e.g., "In general, I consider myself \\[not a very happy person, a very happy person\\]"). It is scored on a 7-point Likert scale where 1 = less happy to 7 = more happy. Total scores range from 4 to 28 where higher scores indicate greater subjective happiness.'}, {'measure': 'Problematic and Risky Internet Use Screening Scale (PRIUSS-3)', 'timeFrame': 'Baseline, week 4, and 3 month follow up', 'description': 'The PRIUSS-3 is a 3-item scale where participants report their level of problematic internet use. It is scored on a 4-point Likert scale where 0 = never to 4 = very often. Total scores range from 0 to 12, where higher scores indicate more problematic internet use.'}]}, 'oversightModule': {'oversightHasDmc': False, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'conditions': ['Depression', 'Psychological Distress']}, 'descriptionModule': {'briefSummary': 'The central aim of this study is to test the efficacy of the Healthy Minds Program (HMP) app, an intervention designed to promote well-being. The investigators plan to conduct a randomized controlled trial (RCT) involving 1100 participants comparing 4-weeks of the HMP app with an active control (Psychoeducation \\[HMP without meditation practice\\]), and a waitlist control in a sample of United States adults with elevated depression symptoms.', 'detailedDescription': 'Depression is highly prevalent and associated with extreme personal and societal costs. Meditation training reduces depression symptoms and psychological distress, but access to in-person programs is limited due to associated cost and lack of available services. Research on neurocognitive and biological mechanisms of meditation training in alleviating depression is at a preliminary stage, and an obstacle limiting research progress is over-reliance on retrospective self-report measures, which are vulnerable to a host of biases. This project will use gold-standard behavioral measures and explore novel measures of relevant neurocognitive and behavioral processes, namely pattern separation, self-referential thought, and video-based assessment of emotional well-being. Furthermore, the project will investigate effects on the gut microbiome (with fecal samples) and inflammation (with dried blood spots), which reflect biological systems hypothesized to be mechanistically related to benefits of meditation and well-being training.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'maximumAge': '65 Years', 'minimumAge': '18 Years', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Elevated PHQ-8 or PHQ-9 ≥ 5 at screening\n* Proficient in English\n* Able to provide informed consent\n* Have access to a smartphone that can download apps from Google Play or the Apple App Store\n* For payment purposes, must be a US citizen or a permanent US resident\n\nExclusion Criteria:\n\n* Regular daily meditation practice for past 6 months or regular weekly meditation practice for past 12 months\n* Attended a meditation retreat or a yoga/body practice retreat with a significant meditation component\n\n \\- Previous use of Healthy Minds Program app\n* Current suicidal intent and/or high self-injury risk (determined from the interview)\n* Self-reported history of psychosis\n* Self-reported history of mania\n* Current psychopathology that interferes with study participation as assessed by interview\n* Living or traveling outside the US during the whole study participation period (trips outside US after the interview phase is not an exclusion)\n* Alcohol Use Disorders Identification Test (AUDIT) score ≥ 13 for women and AUDIT score ≥ 15 for men\n* Drug Use Disorders Identification Test (DUDIT) score ≥ 8 for women and men'}, 'identificationModule': {'nctId': 'NCT05183867', 'acronym': 'BeWell', 'briefTitle': 'Behavior, Biology and Well-Being Study', 'organization': {'class': 'OTHER', 'fullName': 'University of Wisconsin, Madison'}, 'officialTitle': 'Comparing the Healthy Minds Program With an Active Control and Waitlist Control in Depression', 'orgStudyIdInfo': {'id': '2021-0991'}, 'secondaryIdInfos': [{'id': 'Protocol Version 6/29/2023', 'type': 'OTHER', 'domain': 'UW Madison'}, {'id': 'A487400', 'type': 'OTHER', 'domain': 'UW Madison'}, {'id': '1U24AT011289-01', 'link': 'https://reporter.nih.gov/quickSearch/1U24AT011289-01', 'type': 'NIH'}]}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'Healthy Minds Program (HMP) app', 'description': 'Participants will receive access to the 4-week HMP Foundations module. The HMP app is a meditation-based smartphone app designed to promote and protect psychological well-being through sustainable skills training. The program is grounded in constituents of psychological well-being identified in empirical literature. HMP provides core content, with instruction administered through a curriculum of guided practices. HMP is based on research on eudaimonic well-being (e.g., environmental mastery, purpose) and brain-based skills that underlie these qualities (e.g., regulation of attention, mental flexibility). The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.', 'interventionNames': ['Device: Healthy Minds Program']}, {'type': 'ACTIVE_COMPARATOR', 'label': 'Psychoeducation app', 'description': 'Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.', 'interventionNames': ['Device: Healthy Minds Program']}, {'type': 'NO_INTERVENTION', 'label': 'Usual Care', 'description': 'Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.'}], 'interventions': [{'name': 'Healthy Minds Program', 'type': 'DEVICE', 'otherNames': ['HMP'], 'description': 'HMP is a 4-week mobile health (mHealth) meditation training program.', 'armGroupLabels': ['Healthy Minds Program (HMP) app', 'Psychoeducation app']}]}, 'contactsLocationsModule': {'locations': [{'zip': '53703', 'city': 'Madison', 'state': 'Wisconsin', 'country': 'United States', 'facility': 'University of Wisconsin', 'geoPoint': {'lat': 43.07305, 'lon': -89.40123}}], 'overallOfficials': [{'name': 'Simon Goldberg, PhD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'UW-Madison, Center for Healthy Minds'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'NO'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'University of Wisconsin, Madison', 'class': 'OTHER'}, 'collaborators': [{'name': 'Hope for Depression Research Foundation', 'class': 'OTHER'}, {'name': 'National Center for Complementary and Integrative Health (NCCIH)', 'class': 'NIH'}], 'responsibleParty': {'type': 'SPONSOR'}}}}