Ignite Creation Date:
2025-12-25 @ 1:22 AM
Ignite Modification Date:
2025-12-29 @ 10:50 AM
Study NCT ID:
NCT00291993
Status:
COMPLETED
Last Update Posted:
2008-04-21
First Post:
2006-02-13
Is Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Vasoactive Hormones During the Night in Patients With Obstructive Sleep Apnea and Healthy Controls.
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D020181', 'term': 'Sleep Apnea, Obstructive'}], 'ancestors': [{'id': 'D012891', 'term': 'Sleep Apnea Syndromes'}, {'id': 'D001049', 'term': 'Apnea'}, {'id': 'D012120', 'term': 'Respiration Disorders'}, {'id': 'D012140', 'term': 'Respiratory Tract Diseases'}, {'id': 'D020919', 'term': 'Sleep Disorders, Intrinsic'}, {'id': 'D020920', 'term': 'Dyssomnias'}, {'id': 'D012893', 'term': 'Sleep Wake Disorders'}, {'id': 'D009422', 'term': 'Nervous System Diseases'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'PROSPECTIVE'}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2004-01'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2008-04', 'lastUpdateSubmitDate': '2008-04-17', 'studyFirstSubmitDate': '2006-02-13', 'studyFirstSubmitQcDate': '2006-02-13', 'lastUpdatePostDateStruct': {'date': '2008-04-21', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2006-02-15', 'type': 'ESTIMATED'}}, 'conditionsModule': {'keywords': ['Obstructive sleep apnea', 'Vasoactive hormones', 'Blood pressure'], 'conditions': ['Healthy', 'Obstructive Sleep Apnea']}, 'descriptionModule': {'briefSummary': 'Obstructive sleep apnea syndrome is complicated by considerable cardiovascular morbidity and mortality, at least partly due to hypertension. Nocturnal hypoxia, hypercapnia and acidosis stimulate chemoreceptors and presumably increased secretion of vasoactive hormones which might be responsible for hypertension in these patients.\n\nThe aim of this study is to measure the secretion of vasoactive hormones at night and to analyse the relationship between vasoactive hormones, oxygen saturation and the blood pressure at night.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'maximumAge': '65 Years', 'minimumAge': '20 Years', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\nMale and female Age 20-65 Obstructive sleep apnea\n\nExclusion Criteria:\n\nDrug or alcohol abuse Pregnancy or breast feeding Cancer Clinical signs or history of disease in the heart, lungs, kidney or endocrine organs Abnormal laboratory tests Albuminuria or glucosuria Aterial hypertension for healthy subjects'}, 'identificationModule': {'nctId': 'NCT00291993', 'briefTitle': 'Vasoactive Hormones During the Night in Patients With Obstructive Sleep Apnea and Healthy Controls.', 'organization': {'class': 'OTHER', 'fullName': 'Regional Hospital Holstebro'}, 'orgStudyIdInfo': {'id': 'MED.RES.HOS.2004.01.PHH'}}, 'contactsLocationsModule': {'locations': [{'zip': '7500', 'city': 'Holstebro', 'state': 'Ringkoebing County', 'country': 'Denmark', 'facility': 'Department of Medical Research, Holstebro Hospital', 'geoPoint': {'lat': 56.36009, 'lon': 8.61607}}, {'zip': '7500', 'city': 'Holstebro', 'country': 'Denmark', 'facility': 'Department of Medical Research', 'geoPoint': {'lat': 56.36009, 'lon': 8.61607}}, {'zip': '7500', 'city': 'Holstebro', 'country': 'Denmark', 'facility': 'Holstebro Hospital, Department of Medical Research', 'geoPoint': {'lat': 56.36009, 'lon': 8.61607}}], 'overallOfficials': [{'name': 'Erling B Pedersen, Professor', 'role': 'STUDY_CHAIR', 'affiliation': 'Holstebro Hospital, Department of Medical Research'}, {'name': 'Pia H Hansen, MD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Holstebro Hospital, Department of Medical Research'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Regional Hospital Holstebro', 'class': 'OTHER'}}}}