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Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol: GEM
Name: GTP binding protein overexpressed in skeletal muscle
Location: 08q22.1
Locus Group: protein-coding gene
Gene Type: Protein Coding
Locus Type: gene with protein product
ID+ Clinical Trials CompTox DrugMatrix Conditions Design Enrollment Locations Outcomes
Clinical Trials Data: https://classic.clinicaltrials.gov/api/gui/ref/download_all

Clinical Studies

NCT Number Status Brief Title View
NCT00939575 Pre-eclampsia and Metabolomics View
NCT03477643 Retrospective Viability Study of the PETHEMA-POMCIDEX Clinical Practice Guidelines for the Treatment of Patients With Relapsed and Refractory Multiple Myeloma RRMM View
NCT00143013 Gene Expression Profiling and Bioinformatic Analysis Identifying Genes and Biochemical Pathways in Type 2 Diabetes View
NCT00474201 Drug Interaction Study of LopinavirRitonavir and Gemfibrozil View
NCT00505076 Treatment Study for Cognitive Deficits in Schizophrenia View
NCT01071668 Onset of Labor and Metabolomics GEM-2 View
NCT01301443 Phase I Dose Escalation Safety Study of RetinoStat in Advanced Age-Related Macular Degeneration AMD View
NCT01720381 OptiScanner Versus Standard Blood Glucose Monitoring View
NCT01916252 Bortezomib Velcade Lenalidomide Revlimid and IV Busulfan Busilvex in Patients Under 65 Years Old View
NCT01960634 Translational Study for BRAFV600 Serum and Plasma Determination in Patients With BRAFV600 Metastatic Melanoma View
NCT02035072 Phase II Study of Hypofractionated Radio-chemotherapy With Gemcitabine Plus Oxaliplatin for Unresectable Nonmetastatic Locally Advanced Pancreatic Cancer View
NCT02115139 GEM STUDY Radiation And Yervoy in Patients With Melanoma and Brain Metastases View
NCT02761291 Study of Cytolytic Viral Activation Therapy CVAT for RecurrentMetastatic Nasopharyngeal Carcinoma View
NCT02807181 SIRT Followed by CIS-GEM Chemotherapy Versus CIS-GEM Chemotherapy Alone as 1st Line Treatment of Patients With Unresectable Intrahepatic Cholangiocarcinoma View
NCT01210911 Metformin Combined With Chemotherapy for Pancreatic Cancer View
NCT03536143 A Phase III Study of KB103 a Topical HSV1-COL7 on DEB Patients View
NCT04594005 CDK46 Tumor Abemaciclib Paclitaxel View
NCT00388635 Velcade-Melphalan-Prednisone in Older Untreated Multiple Myeloma Patients View
NCT05581498 Glaucoma Exercise as Medicine Study GEMS View
NCT05755061 WEBCAMS Walking Exercise for Brain and Cognition in Adults With Multiple Sclerosis View
NCT02364323 Genetic Testing and Counseling to Reduce Diabetic Complications View
NCT06282978 Study of Elranatamab for Relapsed or Refractory Myeloma in Patients Previously Exposed to Three-drug Classes View
NCT03589222 SELIBORDARA Selinexor Bortezomib and Daratumumab in Multiple Myeloma View
NCT06462066 Effectiveness Appropriateness and Safety of GLUTACK-Glubran Tiss 2 Surgical Glue Compared to GLUTACK-Glubran 2 Device System for Mesh Fastening in Laparoscopic and Robotic Hernia Surgery View
NCT02267083 Efficacy and Safety Study of GPX-150 to Treat Soft Tissue Sarcoma View
NCT06390124 Reconstructive Therapy of Peri-implantitis With PDGF-BB Gem-21 View
NCT02944383 A 12-Week Study to Assess the Efficacy Safety and Tolerability of Gemcabene in Subjects With Severe Hypertriglyceridemia View
NCT03023527 Nivolumab Role in the Treatment of Patients With Refractory or Relapse Multiple Myeloma View
NCT00253968 Efficacy and Safety of Eplivanserin Treatment for Sleep Maintenance Insomnia View
NCT00250822 Gemcitabine and Oxaliplatin for Hepatocellular Carcinoma With Platelet Counts Greater Than 100000 Per Microliter View
NCT00032175 Gemcitabine With or Without Capecitabine in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer View
NCT00079261 Cyclophosphamide Doxorubicin Vincristine and Prednisone With or Without Gemcitabine in Treating Patients With Previously Untreated Aggressive Non-Hodgkins Lymphoma View
NCT00127595 Oxaliplatin With Gemcitabine in Patients With Carcinoma of the Urothelial Tract View
NCT00003403 GPX-100 in Treating Patients With Solid Tumors View
NCT01890369 Modulation of Muscle Protein Metabolism by Essential Amino Acids View
NCT00385606 Study of Rofecoxib and Prolonged Constant Infusion of Gemcitabine in the Polychemotherapy Treatment of Advanced NSCLC View
NCT01407822 Erlotinib Versus GemcitabineCisplatin as NeoAdjuvant Treatment in Non-small Cell Lung Cancer View
NCT01897961 Phospholipase A2 Receptor PLA2R1 Autoantibodies in Membranous Nephropathy in Kidney Transplantation View
NCT00498225 Phase III of Gemcitabine Vs TS-1 Vs Gemcitabine Plus TS-1 in Pancreatic Cancer View
NCT00514163 GEM vs GEMTS-1 for Advanced Pancreatic Cancer View
NCT00539578 Treatment of Patients With Anxiety Disorder 0777-022 View
NCT00546624 GEM 15 mg bid to 45 mg bid Versus Lorazepam in GAD 0777-026 View
NCT00584467 Genetic and Inflammatory Markers in Cardiovascular Disease GEM Registry View
NCT00703833 A Study of MK0777 Gel Extrusion Module GEM in the Treatment of Outpatients With Generalized Anxiety Disorder 0777-019 View
NCT00713687 GemcitabineOxaliplatin and Photodynamic Therapy in Cholangiocarcinoma View
NCT00743717 Evaluation of the Safety and Effectiveness of the Kinamed Gem Ceramic Femoral Component for Total Knee Replacement View
NCT00799916 Saline Solution Versus Voluven A Controlled Study of Fluid Resuscitation in Severe Sepsis View
NCT00832637 Gemcitabine Oxaliplatin Tarceva or Cisplatin in HCC Biliary Tree Cancers View
NCT02211235 Glycemic Monitoring in Cystic Fibrosis View
NCT02060656 Phase II Study Comparing LR-GEM to R-GEM-P in Second-line Treatment of Diffuse Large B-cell Lymphoma LEGEND View
NCT04643886 A Multiple Dose Study of Repeat Intravitreal Injections of GEM103 in Dry Age-related Macular Degeneration View
NCT02081131 Pancreatic Head and Peri-ampullary Cancer Laparoscopic vs Open Surgical Treatment Trial PLOT View
NCT02634151 A 12-Week Phase 2 Study of Gemcabene in Hypercholesterolemia Patients on Stable Moderate and High-Intensity Statins View
NCT01679119 Treatment of Patients With Diffuse Large B Cell Lymphoma Who Are Not Suitable for Anthracycline Containing Chemotherapy View
NCT01048320 Gemcitabine and Oxaliplatin Gem-Ox Plus Glivec in Gemcitabine-refractory Pancreatic Cancer View
NCT01719835 CHOP vs GEM-P in 1st Line Treatment of T-cell Lymphoma Multicentre Phase II Study View
NCT01198821 Gem-TABS in Unresectable Pancreatic Carcinoma View
NCT02415413 Carfilzomib in Treatment Patients Under 65 Years With High Risk Smoldering Multiple Myeloma View
NCT01324258 Trial of GSK1120212 and GSK1120212 in Combination With GEM in Japanese Subjects With Solid Tumors View
NCT01353547 Genes and Environment in Multiple Sclerosis View
NCT03126435 EndoTAG-1GEM vs GEM in Patients With Locally AdvancedMetastatic Pancreatic Adenocarcinoma Failed on FOLFIRINOX View
NCT01797913 The Study of Gemcitabine in the Maintenance Treatment of Advanced Non-small Cell Lung Cancer View
NCT04977206 Engaging Patients in Mutual Goal-Setting in Hospitalized Patients View
NCT01668316 Get Active and Eat Right Moms at Work View
NCT05064618 Investigator-initiated Clinical Trial of MIKE-1 View
NCT05218603 Evaluation of Maintenance With Bortezomib Plus Daratumumab V-Dara After Induction With Bortezomib Melphalan Prednisone Plus Daratumumab VMP-Dara in Newly Diagnosed Multiple Myeloma MM Patients Non-eligible for autoSCT View
NCT03336073 Carfilzomib Cyclophosphamide Dexamethasone in Multiple Myeloma View
NCT01917617 Oral Rehydration Therapy for Short Hydration in Chemotherapy With CDDP Plus GEM for Biliary Tract Cancer View
NCT00502931 A Systematic Review on the Accuracy and Reliability the BodyGemMedGem Metabolic Devices View
NCT05297240 Retrospective Study of the Use of Belantamab Mafodotin Blenrep in Patients With Relapsed andor Refractory Multiple Myeloma RRMM in Spain View
NCT05307237 Continuous Glucose Monitoring for High-Risk Type 2 Diabetes in the Hospital Cyber GEMS View
NCT02069730 A Study of Drug Therapies for Salivary Gland Cancers Based on Testing of Genes View
NCT02117258 Z-360 Plus GEM in Subjects With Metastatic Pancreatic Adenocarcinoma View
NCT02636010 Pembrolizumab MK-3475 in MM Patients With Residual Disease View
NCT02222259 A Feasibility Trial of Geriatric Assessment and Management for Older Cancer Patients View
NCT02910882 PEGPH20 Plus Gemcitabine With Radiotherapy in Patients With Localized Unresectable Pancreatic Cancer View
NCT02272738 A Study of Chemoradiotherapy Using Gem Plus Nab-paclitaxel for Pancreatic Cancer View
NCT05475366 Personalized First-line Chemotherapy Choice in Advanced Pancreatic Adenocarcinoma Using Transcriptomic Signatures View
NCT02295722 GEMHDM2014 Gem-HDM HDT and ASCT for Relapsed Refractory Lymphoma View
NCT02336217 Glycemic Emergency Management GEM An App for Rapid Response to Hypoglycemic and Hyperglycemic Situations View
NCT05527340 Iberdomide-dexamethasone Alone or in Combination With Standard MM Treatment Regimens in Transplant Ineligible Newly Diagnosed Patients View
NCT02356211 Longitudinal Outcome in a Veterans Geriatric Multifactorial Falls Assessment Clinic View
NCT02416609 Low-dose Radiotherapy Plus Chemotherapy With Gem-based Doublets and Stereotactic Radiotherapy for Advanced Pancreatic Cancer View
NCT05580978 CGM Plus GEM in Prediabetes View
NCT05634369 A Multi-Institution Study of TGFβ Imprinted Ex Vivo Expanded Universal Donor NK Cell Infusions As Adoptive Immunotherapy in Combination with Gemcitabine and Docetaxel in Patients with Relapsed or Refractory Pediatric Bone and Soft Tissue View
NCT03727126 Robotic Versus Thoracolaparoscopic Esophagectomy for Esophageal Cancer View
NCT02575144 GEM-CLARIDEX Ld vs BiRd View
NCT02583516 Clinical Trial to Evaluate the Efficacy of Vemurafenib in Combination With Cobimetinib Continuous and Intermittent in BRAFV600-mutation Positive Patients With Unresectable Locally Advanced or Metastatic Melanoma View
NCT02655107 Non-invasive Measurement of Hemoglobin in Infants and Neonates View
NCT05738057 Combined Therapy Using D-TACE Gemcitabine and Cisplatin and PD1 Antibody in Advanced and Unresectable Intrahepatic Cholangiocarcinoma View
NCT02767752 Gemcitabine and Capecitabine With or Without T-ChOS as Adjuvant Therapy for Patients With Resected Pancreatic Cancer View
NCT03790111 A Safety and Efficacy Study of XERMELO First-line Chemotherapy in Patients With Advanced Biliary Tract Cancer View
NCT05809609 Glutamate Emotion Memory Study View
NCT02868268 Neuroblastoma Precision Trial View
NCT01839487 PEGPH20 Plus Nab-Paclitaxel Plus Gemcitabine Compared With Nab-Paclitaxel Plus Gemcitabine in Participants With Stage IV Untreated Pancreatic Cancer View
NCT03006328 The GEM Goals for Eating and Moving Study View
NCT03048968 The Effect of a Walking Assist Robot on Gait Function and Brain Activity in Stroke Patients and Elderly Adults View
NCT03074266 Clinical Performance of the Investigational GEM Hemochron 100 in Populations Ages 18 Years and Older View
NCT03076242 Genetic Evaluation of Men GEM View
NCT04491604 Ph 3 Efficacy and Safety of B-VEC for the Treatment of DEB View
NCT03191318 Comparison of Enhanced Recovery After Surgery ERAS Pathway With Conventional Pathway After Laparoscopic Sleeve Gastrectomy View
NCT03207893 Benefits of Continuous Glucose Monitoring With GEM Lifestyle Modification for Adults With Type 2 Diabetes View
NCT03267940 Study of PEGPH20 With Cisplatin CIS and Gemcitabine GEM PEGPH20 With Atezolizumab ATEZO CIS and GEM and CIS and GEM Alone in Participants With Previously Untreated Unresectable Locally Advanced or Metastatic Intrahepatic and Extrahepatic Cholangiocarcinoma and Gallbladder Adenocarcinoma View
NCT04769414 Flouro-Gem in Adenocarcinoma of the Pancreas GEFLUPAN View
NCT04610190 Useability Test to the Wearable Walking-assist Robot GEMS-H for Normal Adults Including the Elderly View
NCT04786327 Minimally Invasive Flap With Platelet Rich Fibrin or Growth Factor Enhanced Matrix in Treatment of Intrabony Defect View
NCT03389165 The Effect of a Wearable Hip Assist Robot on Cardiopulmonary Metabolic Efficiency During Stair Ascent in Elderly Adults View
NCT03898908 Encorafenib and Binimetinib Before Local Treatment in Patients With BRAF Mutant Melanoma Metastatic to the Brain View
NCT06257004 Genome-wide Epistasis for Cardiovascular Severity in Marfan Study View
NCT03563092 Closed Suction Drain vs no Drain on Symptomatic Seroma Formation After Laparoscopic Inguinal Hernia Repair View
NCT03605771 Descriptive Observational Study on the Characteristics of Advanced and Metastatic Melanoma in Spain View
NCT03649217 Active Limb Orthosis for Home-Use Stroke Hemiparetic Gait Rehabilitation View
NCT04920201 The Effect of Exercise With Wearable Walking Assist Robot in Various Environments View
NCT06381349 Predicting Outcomes of GPOEM Using Gastric Electrical Mapping View
NCT03816163 A Study of Zolbetuximab IMAB362 in Adults With Pancreatic Cancer View
NCT04961658 Advanced Mesenchymal Enhanced Cell THerapY for SepTic Patients View
NCT03962517 Effect of GEMS-H on Locomotor Function in Adults View
NCT05006482 Geriatric Evaluation and Management With Survivorship Health Education GEMS for Older Survivors of Cancer View
NCT06505486 GEMOX-HAIC Plus GEM-SYS in Combination With Lenvatinib and PD-1 Inhibitor for Large Unresectable ICC View
NCT00599755 Phase I Imaging Study Evaluating GemCis or GemCarbo for Participants With Non-Small Cell Lung Cancer MK-0000-083 AM3 View
NCT05060627 Study of Belantamab Mafodotin in Combination With Kd for the Treatment of Relapsed Myeloma Patients Refractory to Lenalidomide View
NCT06574126 Ciltacabtagene Autoleucel in High-Risk Smoldering Multiple Myeloma View
NCT04184518 Durvalumab MEDI4736 Plus Cediranib in Patients With Metastatic Uveal Melanoma View
NCT04216758 Nab-P and Gem Compared With Gem and Tegafur in Adjuvant Chemotherapy After Radical Resection of Pancreatic Cancer View
NCT04246866 First in Human Study to Evaluate the Safety and Tolerability of GEM103 in Geographic Atrophy Secondary to Dry Age Related Macular Degeneration View
NCT04285060 Safety and Efficacy of Samsung GEMS-H Device Training in Sub-Acute and Chronic Stroke View
NCT05711758 Efficacy and Safety of Endoscopic Antral Myotomy as a Novel Weight Loss Procedure View
NCT02626962 Trial of Nivolumab in Combination With Ipilimumab in Subjects With Previously Untreated Metastatic Uveal Melanoma View
NCT00583375 Augment Bone Graft Formerly GEM OS1 Bone Graft Compared to Autologous Bone Graft in Foot and Ankle Fusions View
NCT05784714 NOLA GEM Feasibility and Acceptability of an mHealth Intervention for Violence-affected PLWH View
NCT04597801 Comparison of Fluorescein-INtra-VItal Microscopy Versus Conventional Frozen Section Diagnosis for intraOperative Histopathological Evaluation View
NCT05820906 Cadonilimab Plus Regorafenib and Gem-Cis Chemotherapy in Advanced Biliary Tract Cancer View
NCT04632849 The Use of Libre to Improve Metabolic Control and Reduce Reliance on Medication View
NCT04652336 Study Comparing the Effect of Ligamentum Teres Cardiopexy on de Novo GERD Post LSG View
NCT05849610 Teclistamab-Daratumumab and Talquestamab-Daratumumab in Newly Diagnosed High-risk Multiple Myeloma View
NCT04684394 A Multiple Dose Study of Repeat Intravitreal Injections of GEM103 in Neovascular Age-related Macular Degeneration View
NCT05874726 Biological Sample Repository for Gastrointestinal Disorders View
NCT06050265 Glucose Evaluation Through Continuous Glucose Monitors in Polycystic Ovary Syndrome View
NCT04802356 Belantamab Mafodotin in Newly Diagnosed Transplant Eligible Multiple Myeloma Patients View
NCT06079593 GaslEss Macular Hole Surgery View
NCT06085677 The Gastric HormonE BioMarkers of Preneoplastic Lesions Study View
NCT04964466 Release Kinetics in PRF Versus GEM21S With and Without Bone Substitutes An In Vitro Analysis View
NCT00004864 Docetaxel and GEM 231 in Treating Patients With Recurrent or Refractory Solid Tumors View
NCT05083247 Preoperative mFOLFIRINOX or Gem-Nab-P - Isotoxic High-dose SBRT for Borderline Resectable Pancreatic Adenocarcinoma View
NCT05106881 Usability and Satisfaction Test to the Wearable Walking-assist Robot GEMS-H in the Community-dwelling Healthy Adults View
NCT05197127 Efficacy of Samsung GEMS-H Device Training in Older Adults View
NCT05211518 Prevention of Inflammatory Bowel Diseases in Persons at Risk The PIONIR Preventing IBD Onset in Individuals at Risk Trial View
NCT05329597 Study on Umorestat Hydrogen Sulfate Capsule in Patients With Locally AdvancedMetastatic Pancreatic Cancer View
NCT06546943 Glucose Monitoring in Youth With Cystic Fibrosis During Pulmonary Exacerbations View
NCT05566587 Designing a Personalized Diet to Reduce the Risk of Crohns Disease Onset View
NCT00710125 Safety Study of GPX-150 in Patients With Solid Tumors View
NCT05712694 Study of ADI-PEG 20 or Placebo Plus Gem and Doc in Previously Treated Subjects With Leiomyosarcoma ARGSARC View
NCT05725967 Endoscopic Metabolic and Bariatric Therapies View
NCT05766735 Treating Early Type 2 Diabetes by Reducing Postprandial Glucose Excursions A Paradigm Shift in Lifestyle Modification View
NCT05776524 Study of Amplitude-Modulated Radiofrequency Electromagnetic Fields in Metastatic Pancreatic Cancer View
NCT02032628 DNA Methylation and Cancer Prevention Duration and Intensity of Exercise View
NCT05782751 Growth Factor Enhanced Matrix With Subepithelial Connective Tissue Graft or Collagen Membrane in Treatment of Gingival Recession View
NCT05827055 Proglumide and Chemotherapy for Metastatic Pancreatic Cancer View
NCT00138658 A Study of OGX-011GemcitabinePlatinum-Based Regimen in Stage IIIBIV Non-Small Cell Lung Cancer NSCLC View
NCT06236581 Glycemic Excursion Minimization GEM to Outshine Health Disparities View
NCT00191269 Gemcitabine Monotherapy for Metastatic Breast Cancer After Anthracycline and Taxane Regimen View
NCT00191971 2nd Line Gemcitabine Monotherapy for Transitional Cell Carcinoma of Urothelium TCC After CDDP Regimen View
NCT06327932 HIVEC in Patients With Non-Muscle-Invasive Bladder Cancer View
NCT06365411 GEnomic Medicine in Kidney Transplantation Study View
NCT00004863 Paclitaxel and GEM 231 in Treating Patients With Recurrent or Refractory Solid Tumors View
NCT03940443 Differences in Mortality and Morbidity in Patients Suffering a Time-critical Condition Between GEMS and HEMS View
NCT02132403 PM-01 IMPRIME PGG With BTH1704 and Gemcitabine for Advanced Pancreatic Cancer View
NCT01838577 Genetics of EGFR Epidermal Growth Factor Receptor Mutation Study View
NCT02162914 Regorafenib Versus Placebo to Treat Cholangiocarcinoma View
NCT00000615 Girls Health Enrichment Multi-Site Studies GEMS View
NCT05861336 GEMNab-Paclitaxel Plus Losartan Followed by Stereotactic Radiotherapy for Locally Advanced Pancreatic Cancer View
NCT02185404 iStrideTM Device Used for Stroke Rehabilitation View
NCT05442034 Rh-PDGF vs EMD for Treatment of Intra-bony Defects View
NCT05561413 Gynaecology Exercise and Mindfulness Study View
NCT00178698 HyperthermiaThermal Therapy With Chemotherapy to Treat Inoperable or Metastatic Tumors View
NCT00289471 Identifying Patients With Dementia in Primary Care View
NCT00293345 3-AP and Gemcitabine in Treating Patients With Advanced Solid Tumors or Lymphoma View
NCT00123877 Study of GPX-100 in the Treatment of Metastatic Breast Cancer View
NCT00301301 A Retrospective Review of Gemcitabine Methylprednisolone Cisplatin GEM-P With or Without Rituximab in Patients With RelapsedRefractory Diffuse Large B Cell Lymphoma DLBCL View
NCT00363610 A Study Evaluating IV Oncaspar and IV Gemzar in the Treatment of Solid Tumors and Lymphoma View
NCT00551122 Gemcitabine Paclitaxel Ifosfamide and Cisplatin in Treating Patients With Progressive or Relapsed Metastatic Germ Cell Tumors View
NCT02432391 Lifestyle Modification for Type 2 Diabetes Involving Reduction of After-meal Blood Glucose Elevations View
NCT02576379 The Impact of a Helicopter Emergency Medical System on Prognosis in Stroke Patients View
NCT02722408 Efficacy and Safety of Gemcabene in Patients With Homozygous Familial Hypercholesterolemia on Stable Lipid-Lowering Therapy COBALT-1 View
NCT02957981 The Genetic Education for Men Trial Web-Based Education vs Standard Care View
NCT03342040 Transverse Abdominis Plane Block in Laparoscopic Ventral Hernia Repair View
NCT03497052 Culture Media and Blastocyst Development View
NCT03722056 Laparoscopic Management of Gastrointestinal Stromal Tumor of Stomach View
NCT03736057 Genetic Evaluation for Medication Selection GEMS Study View
NCT03890146 Concordance of Capillary Blood Biological Samples With Conventional Venousbiological Blood Samples View
NCT03995238 Optimizing Gait Rehabilitation for Veterans With Non-traumatic Lower Limb Amputation View