Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
CYP3A5
Name:
cytochrome P450 family 3 subfamily A member 5
Location:
07q22.1
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
Clinical Trials Data: https://classic.clinicaltrials.gov/api/gui/ref/download_all
Clinical Studies
| NCT Number | Status | Brief Title | View |
|---|---|---|---|
| NCT00245986 | Effect of Genetics on Metabolism of Efavirenz | View | |
| NCT00637234 | Oxcarbazepine as an Adjunct of Antipsychotic Therapy in Acute Schizophrenia | View | |
| NCT00935298 | Initial Dosage Range of Tacrolimus by Genotyping in Chinese Renal Transplantation | View | |
| NCT01059747 | Therapeutic Drug Monitoring and Pharmacogenomics Study of Methadone Therapy | View | |
| NCT01663077 | Clozapine Plasma Levels and the Relationship to the Genetic Polymorphism in Shizophrenic Patients | View | |
| NCT02877628 | Immunosuppressive Therapy Optimization Development of a Population Pharmacokinetic-pharmacodynamic PK-PD Model in Liver Transplantation | View | |
| NCT02191358 | YouScript IMPACT Registry | View | |
| NCT03076151 | Pharmacokinetic Study of Adoport Tacrolimus in Patients With de Novo Kidney Transplantation | View | |
| NCT06361732 | Prevalence of CYP3A5 Polymorphisms in the Donors and ABCB1 Polymorphisms in the Recipients Undergoing Pediatric Liver Transplant and Their Influence on Tacrolimus Levels and Graft Function | View | |
| NCT00552201 | TACrolimus in Renal Transplantation Individualization by Pharmacogenetic | View | |
| NCT06319391 | Analysis of the Effect of Donor CYP3A5 Gene Polymorphism on Early Tacrolimus Concentration and Postoperative Acute Renal Injury After Liver Transplantation | View | |
| NCT01110291 | Study of Usefulness of Genotyping to Predict Docetaxel Exposure and Adverse Events | View | |
| NCT00139035 | Effects of Cyclosporine A on Pancreatic Insulin Secretion | View | |
| NCT01884480 | Renal Function and Pharmacogenetics in Renal Transplant Recipients Converted From Tac BID to Tac OD | View | |
| NCT00411944 | Long-Term Pharmacokinetics of Tacrolimus in Renal Recipients | View | |
| NCT01388387 | Pharmacogenetic Study of Tacrolimus in Hepatic Transplant CYPTACH | View | |
| NCT00514345 | CYP3A5 Gene as a Risk Factor for Kidney Damage in Young Patients With Cancer Treated With Ifosfamide | View | |
| NCT00767598 | The Effect of CYP3A Genetic Polymorphism on the Pharmacokinetics of Phosphodiesterase type5 Inhibitors in Male Subjects | View | |
| NCT01980329 | Polymorphic Effects of Cytochrome P450 3A5 on Pharmacokinetics of Maraviroc and Its Metabolites | View | |
| NCT00796029 | A Study of Plasma Concentrations Metabolism and Excretion of 14C-paliperidone After a Single Oral Dose | View | |
| NCT00824772 | Evaluation of Pharmacogenetic Factors Affecting Fentanyl Requirements for Postoperative Pain Control | View | |
| NCT02707822 | The Influence of ABCB1CYP3A4CYP3A5POR Genetic Polymorphism and Other Factors on Tacrolimus Blood Concentration | View | |
| NCT04645667 | Tacrolimus in Allogeneic Hematopoietic Stem Cell Transplant HCT | View | |
| NCT04657679 | Pharmacokinetics and Pharmacogenomics of Ribociclib in Race-based Cohorts | View | |
| NCT01160276 | Drug Interaction Between Colchicine and Calcineurin Inhibitors in Renal Graft Recipients | View | |
| NCT01259973 | Typical Versus Atypical Antipsychotics Occupation of Striatal Receptors and the Appearance of Extrapyramidal Symptomatology in Healthy Volunteers | View | |
| NCT01288521 | Pharmacogenetics to Predict Drug Interactions in Kidney Transplant Recipients | View | |
| NCT01388543 | Genetics and HIV-1 Protease Inhibitors | View | |
| NCT01425229 | Influence of OATP1B1 and CYP2C9 Genotypes on the Pharmacokinetics of Bosentan Before and During Clarithromycin | View | |
| NCT01482117 | The Effect of Genetic Polymorphism on Interactions of Clopidogrel and Cilostazol in Healthy Volunteers | View | |
| NCT03020589 | Study of Pharmacogenomic-Guided Tacrolimus Dosing and Monitoring in Kidney Transplant Recipients | View | |
| NCT02356146 | First Tacrolimus Dose Trough Level is Better Than CYP3A5 Genotyping in Tacrolimus Dose Prediction | View | |
| NCT02377791 | Impact of CYP3A5 Gene Polymorphisms on Tacrolimus Concentrations and Outcomes in Thai Transplant Recipients | View | |
| NCT02428660 | Drug Gene Interaction Risk Analysis With Without Genetic Testing Among Patients Undergoing MTM | View | |
| NCT03830255 | Effect of Genetic Polymorphism on Calcineurin Inhibitors Levels in Egyptian Renal Transplant Patients | View | |
| NCT02956005 | Envarsus XR in African American Renal Transplant Recipients | View | |
| NCT05490511 | Drug-gene-nutraceutical Interactions of Cannabidiol and Tacrolimus | View | |
| NCT03465410 | OPTImization of the Dose of tacroliMUS by Bayesian Prediction | View | |
| NCT04657562 | The New LC-MSMS Method for Determination of Unbound Tacrolimus in Plasma | View | |
| NCT04825262 | Efficacy of Achieving Early Target Trough Levels of Tacrolimus Using CYP3A5 Guided Dosing Versus Weight-based Dosing in a Multi-ethnic Population of Kidney Transplant Recipients in Singapore | View | |
| NCT02625207 | THE EFFECT OF CYP3A5 GENOTYPE ON THE PHARMACOKINETICS OF MARAVIROC | View | |
| NCT04917718 | Renal Tubular Injury and Transplant Outcomes in Cardiac Recipients Converting From IR Tacrolimus to XR Tacrolimus | View | |
| NCT02014103 | Conversion From Brand to Generic Tacrolimus in High Risk Transplant Recipients | View | |
| NCT00902460 | CP-690550 and Midazolam Drug-Drug Interaction Study | View | |
| NCT06044558 | Effect of AzoleEchinocandin Use on Tacrolimus Pharmacokinetics | View | |
| NCT00728858 | The Efficacy Safety and Genetic Polymorphism of Hypoca and Adalat OROS in Hypertensive Patients | View | |
| NCT00264355 | Metabolic Pattern of Cyclosporine A and Acute Renal Failure | View | |
| NCT00352547 | Influence of Genes on Sirolimus Metabolism in Patients With Kidney Transplantation | View | |
| NCT00796185 | As Study of the Pharmacokinetics of Paliperidone Extended-release and Risperidone Immediate-release Formulations | View | |
| NCT02882113 | Influence of CYP3A5 Polymorphism on Liver Function Abnormality and the Trough Level Change After Conversion | View | |
| NCT03173820 | Clinical Trial in Assigning of Tacrolimus Dosage Regimen According to CYP3A5 Genotype in Kidney Transplant Recipients | View | |
| NCT03222687 | Tacrolimus in Children With Henoch-Schönlein Purpura Nephritis | View |