Viewing Gene With DrugMatrix Data

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Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol: ITGB2
Name: integrin subunit beta 2
Location: 21q22.3
Locus Group: protein-coding gene
Gene Type: Protein Coding
Locus Type: gene with protein product
ID+ Clinical Trials CompTox DrugMatrix Conditions Design Enrollment Locations Outcomes
DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
Gene | Activity | Annotation | GO | Identifier | Pathway | Signature | Simple | Tissue
Target | Accession | Expression | Synonym | Pathway Gene | Gene Platform | Pathway Target
DrugMatrix Gene Go Report Data For: 19 Matched Genes
Gene Name: integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)
View DrugMatrix Gene GO
Category: CELLULAR COMPONENT
Go ID: GO:0008305
Term: INTEGRIN COMPLEX
Gene Name: integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)
View DrugMatrix Gene GO
Category: CELLULAR COMPONENT
Go ID: GO:0016021
Term: INTEGRAL TO MEMBRANE
Gene Name: integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)
View DrugMatrix Gene GO
Category: MOLECULAR FUNCTION
Go ID: GO:0004872
Term: RECEPTOR ACTIVITY
Gene Name: integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)
View DrugMatrix Gene GO
Category: MOLECULAR FUNCTION
Go ID: GO:0019901
Term: PROTEIN KINASE BINDING
Gene Name: integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)
View DrugMatrix Gene GO
Category: MOLECULAR FUNCTION
Go ID: GO:0005515
Term: PROTEIN BINDING
Gene Name: integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)
View DrugMatrix Gene GO
Category: BIOLOGICAL PROCESS
Go ID: GO:0050730
Term: REGULATION OF PEPTIDYL-TYROSINE PHOSPHORYLATION
Gene Name: integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)
View DrugMatrix Gene GO
Category: BIOLOGICAL PROCESS
Go ID: GO:0050730
Term: REGULATION OF PEPTIDYL-TYROSINE PHOSPHORYLA...
Gene Name: integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)
View DrugMatrix Gene GO
Category: BIOLOGICAL PROCESS
Go ID: GO:0007159
Term: LEUKOCYTE ADHESION
Gene Name: integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)
View DrugMatrix Gene GO
Category: BIOLOGICAL PROCESS
Go ID: GO:0019735
Term: ANTIMICROBIAL HUMORAL RESPONSE (SENSU VERTE...
Gene Name: integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)
View DrugMatrix Gene GO
Category: BIOLOGICAL PROCESS
Go ID: GO:0030593
Term: NEUTROPHIL CHEMOTAXIS
Gene Name: integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)
View DrugMatrix Gene GO
Category: BIOLOGICAL PROCESS
Go ID: GO:0019735
Term: ANTIMICROBIAL HUMORAL RESPONSE (SENSU VERTEBRATA)
Gene Name: integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)
View DrugMatrix Gene GO
Category: BIOLOGICAL PROCESS
Go ID: GO:0007229
Term: INTEGRIN-MEDIATED SIGNALING PATHWAY
Gene Name: integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)
View DrugMatrix Gene GO
Category: BIOLOGICAL PROCESS
Go ID: GO:0008360
Term: REGULATION OF CELL SHAPE
Gene Name: integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)
View DrugMatrix Gene GO
Category: BIOLOGICAL PROCESS
Go ID: GO:0007275
Term: DEVELOPMENT
Gene Name: integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)
View DrugMatrix Gene GO
Category: BIOLOGICAL PROCESS
Go ID: GO:0006954
Term: INFLAMMATORY RESPONSE
Gene Name: integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)
View DrugMatrix Gene GO
Category: BIOLOGICAL PROCESS
Go ID: GO:0007160
Term: CELL-MATRIX ADHESION
Gene Name: integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)
View DrugMatrix Gene GO
Category: BIOLOGICAL PROCESS
Go ID: GO:0007267
Term: CELL-CELL SIGNALING
Gene Name: integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)
View DrugMatrix Gene GO
Category: BIOLOGICAL PROCESS
Go ID: GO:0007155
Term: CELL ADHESION
Gene Name: integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)
View DrugMatrix Gene GO
Category: BIOLOGICAL PROCESS
Go ID: GO:0006915
Term: APOPTOSIS