Viewing Gene With DrugMatrix Data


Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/

Symbol: MAPKAPK5
Name: MAPK activated protein kinase 5
Location: 12q24.12-q24.13
Locus Group: protein-coding gene
Gene Type: Protein Coding
Locus Type: gene with protein product

DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
DrugMatrix Gene Data For: 1 Matched Gene
Gene Name: mitogen-activated protein kinase-activated protein kinase 5
Symbol:
Species: 1000
Description: The protein encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported.