Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
SDHA
Name:
succinate dehydrogenase complex flavoprotein subunit A
Location:
05p15.33
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
DrugMatrix Gene Data For: 1 Matched Gene
Gene Name: succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
Symbol:
Description: Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The 70 kDa flavoprotein subunit contains a characteristic cysteine triplet. Mutations in the flavoprotein subunit gene have been linked to a form of mitochondrial respiratory chain deficiency known as Leigh syndrome.