Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
SETDB2
Name:
SET domain bifurcated histone lysine methyltransferase 2
Location:
13q14.2
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
DrugMatrix Gene Data For: 1 Matched Gene
Gene Name: SET domain, bifurcated 2
Symbol:
Description: Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 (see MIM 601128) methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity (Zhang et al., 2003).[supplied by OMIM]