Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
TLR4
Name:
toll like receptor 4
Location:
09q33.1
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
DrugMatrix Gene Go Report Data For: 25 Matched Genes
Gene Name: toll-like receptor 4
Category: CELLULAR COMPONENT
Go ID: GO:0046696
Term: LIPOPOLYSACCHARIDE RECEPTOR COMPLEX
Gene Name: toll-like receptor 4
Category: CELLULAR COMPONENT
Go ID: GO:0005887
Term: INTEGRAL TO PLASMA MEMBRANE
Gene Name: toll-like receptor 4
Category: CELLULAR COMPONENT
Go ID: GO:0016021
Term: INTEGRAL TO MEMBRANE
Gene Name: toll-like receptor 4
Category: CELLULAR COMPONENT
Go ID: GO:0016020
Gene Name: toll-like receptor 4
Category: MOLECULAR FUNCTION
Go ID: GO:0004888
Term: TRANSMEMBRANE RECEPTOR ACTIVITY
Gene Name: toll-like receptor 4
Category: MOLECULAR FUNCTION
Go ID: GO:0001530
Term: LIPOPOLYSACCHARIDE BINDING
Gene Name: toll-like receptor 4
Category: BIOLOGICAL PROCESS
Go ID: GO:0045410
Term: POSITIVE REGULATION OF INTERLEUKIN-6 BIOSYN...
Gene Name: toll-like receptor 4
Category: BIOLOGICAL PROCESS
Go ID: GO:0045368
Term: POSITIVE REGULATION OF INTERLEUKIN-13 BIOSY...
Gene Name: toll-like receptor 4
Category: BIOLOGICAL PROCESS
Go ID: GO:0045084
Term: POSITIVE REGULATION OF INTERLEUKIN-12 BIOSY...
Gene Name: toll-like receptor 4
Category: BIOLOGICAL PROCESS
Go ID: GO:0045362
Term: POSITIVE REGULATION OF INTERLEUKIN-1 BIOSYN...
Gene Name: toll-like receptor 4
Category: BIOLOGICAL PROCESS
Go ID: GO:0045671
Term: NEGATIVE REGULATION OF OSTEOCLAST DIFFERENT...
Gene Name: toll-like receptor 4
Category: BIOLOGICAL PROCESS
Go ID: GO:0045576
Term: MAST CELL ACTIVATION
Gene Name: toll-like receptor 4
Category: BIOLOGICAL PROCESS
Go ID: GO:0009598
Term: DETECTION OF PATHOGENIC BACTERIA
Gene Name: toll-like receptor 4
Category: BIOLOGICAL PROCESS
Go ID: GO:0016046
Gene Name: toll-like receptor 4
Category: BIOLOGICAL PROCESS
Go ID: GO:0042088
Term: T-HELPER 1 TYPE IMMUNE RESPONSE
Gene Name: toll-like receptor 4
Category: BIOLOGICAL PROCESS
Go ID: GO:0045410
Term: POSITIVE REGULATION OF INTERLEUKIN-6 BIOSYNTHESIS
Gene Name: toll-like receptor 4
Category: BIOLOGICAL PROCESS
Go ID: GO:0045368
Term: POSITIVE REGULATION OF INTERLEUKIN-13 BIOSYNTHESIS
Gene Name: toll-like receptor 4
Category: BIOLOGICAL PROCESS
Go ID: GO:0045084
Term: POSITIVE REGULATION OF INTERLEUKIN-12 BIOSYNTHESIS
Gene Name: toll-like receptor 4
Category: BIOLOGICAL PROCESS
Go ID: GO:0045362
Term: POSITIVE REGULATION OF INTERLEUKIN-1 BIOSYNTHESIS
Gene Name: toll-like receptor 4
Category: BIOLOGICAL PROCESS
Go ID: GO:0045671
Term: NEGATIVE REGULATION OF OSTEOCLAST DIFFERENTIATION
Gene Name: toll-like receptor 4
Category: BIOLOGICAL PROCESS
Go ID: GO:0042116
Term: MACROPHAGE ACTIVATION
Gene Name: toll-like receptor 4
Category: BIOLOGICAL PROCESS
Go ID: GO:0007165
Term: SIGNAL TRANSDUCTION
Gene Name: toll-like receptor 4
Category: BIOLOGICAL PROCESS
Go ID: GO:0006954
Term: INFLAMMATORY RESPONSE
Gene Name: toll-like receptor 4
Category: BIOLOGICAL PROCESS
Go ID: GO:0006955
Gene Name: toll-like receptor 4
Category: BIOLOGICAL PROCESS
Go ID: GO:0007250
Term: ACTIVATION OF NF-KAPPAB-INDUCING KINASE
