Gene List

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Gene List
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Symbol Type Of Gene Taxonomy ID Gene ID Description View
GPR85 - Orphan receptor. View
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ZNF660 - - View
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GRIN2C - N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term … View
SEMA4A - SEMA4A is a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in guidance of axonal … View
SEMG2 - The secreted protein encoded by this gene is involved in the formation of a gel matrix that encases ejaculated spermatozoa. … View
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RNF122 - The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins … View
GPR111 - Orphan receptor. View
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MPI - Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose … View
ITLN1 - May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components … View
RBM14 - - View
ACADL - The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved … View
CHST6 - Catalyzes the transfer of sulfate to position 6 of non- reducing N-acetylglucosamine (GlcNAc) residues of keratan. Mediates sulfation of keratan … View
PRSS11 - This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is … View
TCTE1L - - View
PRM1 - Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into … View
RRAGC - RRAGC is a monomeric guanine nucleotide-binding protein, or G protein. By binding GTP or GDP, small G proteins act as … View
CALR3 - Molecular calcium binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin … View
EMP2 - - View
PGLYRP2 - Peptidoglycan recognition proteins, such as PGRPL, are part of the innate immune system and recognize peptidoglycan, a ubiquitous component of … View
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NRF1 - Gopalakrishnan and Scarpulla (1995) noted that the electron transport chain and oxidative phosphorylation system rely on the functional interplay of … View
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MAP1LC3A - MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and … View
RASGRP2 - The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem … View
ANKRD20A - - View
FBXO11 - This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, … View
HIST1H2BM - Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules … View
FA2H - - View
OR10H1 - Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a … View
BET1 - The protein encoded by this gene is a homolog of yeast Bet1 protein which is a golgi-associated protein that participates … View
LMO2 - LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central … View
DBH - The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. It is … View
- - This gene encodes the substrate of breast tumor kinase, an Src-type non-receptor tyrosine kinase. The encoded protein possesses domains and … View
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- - Has antibacterial activity (By similarity). View
SMAD7 - Antagonist of signaling by TGF-beta (Transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF-beta (Transforming … View
DNAJB1 - Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP. View
TMEM16A - - View
DOK5 - The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins … View
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SPIRE1 - Spire proteins, such as SPIRE1, are highly conserved between species. They belong to the family of Wiskott-Aldrich homology region-2 (WH2) … View
MYO5C - May be involved in transferrin trafficking. Likely to power actin-based membrane trafficking in many physiologically crucial tissues. View
NUMBL - - View
ZNF358 - May function as a transcription factor. View
DNCL2B - May be involved in assembly and motor function of dynein, which plays a central role in cell division and intracellular … View
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GDF2 - The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. … View
SIGLEC5 - Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha2,3-linked and alpha2,6-linked sialic acid. The sialic … View
SC5DL - This gene encodes an enzyme that is involved in cholesterol biosynthesis. It is thought to be an integral membrane protein. View
BNC1 - The protein encoded by this gene is a zinc finger protein present in the basal cell layer of the epidermis … View
ABHD2 - This gene encodes a protein containing an alpha/beta hydrolase fold, which is a catalytic domain found in a very wide … View
ADAM5 - - View
Padi3 - catalyzes deimination of arginine residues of proteins in the presence of calcium ions [RGD] View
SNAPC3 - Complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence … View
APH1A - APH1 is a multipass transmembrane protein that interacts with presenilin (see PSEN1; MIM 104311) and nicastrin (APH2; MIM 605254) as … View
DEFB125 - Defensins are cysteine-rich cationic polypeptides that are important in the host immunologic response to invading microorganisms. The protein encoded by … View
SLC23A1 - The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. This … View
KIF2B - - View
SELE - The endothelial leukocyte adhesion molecule-1 is expressed by cytokine-stimulated endothelial cells. It is thought to be responsible for the accumulation … View
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KCNH2 - This gene encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go … View
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Dnm3 - putative dynamin GTPase; may be involved in endocytosis [RGD] View
OR8B2 - Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a … View
PLEKHG6 - - View
MMP28 - Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix for both normal physiological processes, … View
E2F4 - The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays … View
CST1 - The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while … View
GLIS2 - Members of the Kruppel-like zinc finger protein family, such as GLIS2, function as activators and/or repressors of gene transcription.[supplied by … View
CUTL2 - May be a transcription factor involved in neural specification. Binds to DNA in a sequence-specific manner (By similarity). View
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C11orf10 - - View
NAP1L2 - This gene encodes a member of the nucleosome assembly protein (NAP) family. The function of this family member is unknown; … View
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PASK - PAS domains regulate the function of many intracellular signaling pathways in response to both extrinsic and intrinsic stimuli. PAS kinase, … View
POP7 - Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'ends. View
CNR1 - This gene encodes a protein that is one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are … View
UBE2D4 - - View
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HIST1H2AJ - Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules … View
PNRC1 - Nuclear receptor coactivator. May play a role in signal transduction. View
MICAL1 - May be a cytoskeletal regulator that connects NEDD9 to intermediate filaments. View
CACNB3 - The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, … View
KRTAP1-3 - This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate … View
RAMP3 - The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity … View
CBR3 - Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding … View
DEDD2 - May play a critical role in death receptor-induced apoptosis and may target CASP8 and CASP10 to the nucleus. May regulate … View
FUT6 - The alpha-1,3-fucosyltransferases constitute a large family of glycosyltransferases with a high degree of homology. The enzymes of this family comprise … View
CCNI - The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic … View
TTBK2 - - View
Nlgn3 - neuronal cell surface protein that binds neurexins [RGD] View
DFFB - Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied … View
LIMS3 - - View
TRAM2 - TRAM2 is a component of the translocon, a gated macromolecular channel that controls the posttranslational processing of nascent secretory and … View
STX7 - May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic … View
C22orf3 - - View
GALM - - View
CDKN1A - This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or … View
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GCM1 - This gene encodes a DNA-binding protein with a gcm-motif (glial cell missing motif). The encoded protein is a homolog of … View
AK3L1 - This gene encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial … View
TEX27 - - View
ABCB7 - The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins … View
NR4A3 - This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcriptional activator. … View
SSNA1 - - View
XRN2 - This gene shares similarity with the mouse Dhm1 and the yeast dhp1 gene. The yeast gene is involved in homologous … View
FCER1A - The IgE receptor plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and … View
C7orf34 - - View
FOXG1B - This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific … View
COLQ - This gene encodes the subunit of a collagen-like molecule associated with acetylcholinesterase in skeletal muscle. Each molecule is composed of … View
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VMD2L1 - The VMD2 gene (MIM 607854) underlying vitelliform macular dystrophy and the 3 VMD2-like genes, VMD2L1, VMD2L2 (MIM 607336), and VMD2L3 … View
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FAM57B - - View
ATP13A4 - - View
MAPK12 - Activation of members of the mitogen-activated protein kinase family is a major mechanism for transduction of extracellular signals. Stress-activated protein … View
KIAA0690 - - View
CA4 - Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate … View
C6orf27 - - View
C14orf105 - - View
NALP12 - May mediate activation of CASP1 via ASC and promote activation of NF-kappa-B via IKK. View
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MYH1 - Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP. Myosin is … View
PIGF - This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid which contains three … View
HBXIP - This gene encodes a protein that specifically complexes with the C-terminus of hepatitis B virus X protein (HBx). The function … View
RPA2 - Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions. View
SMYD1 - Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis (By similarity). View
PSMD2 - The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core … View
C1QTNF4 - - View
ARHGEF1 - Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G … View
COL6A2 - This gene encodes one of the three alpha chains of type VI collagen, a beaded filament collagen found in most … View
CP - Ceruloplasmin is a plasma metalloprotein that that binds most of the copper in plasma. Human ceruloplasmin is composed of a … View
ZNF274 - This gene encodes a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated box A (KRAB … View
PFKFB2 - The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that … View
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CIRBP - Seems to play an essential role in cold-induced suppression of cell proliferation. View
PFKFB3 - Synthesis and degradation of fructose 2,6-bisphosphate. View
TOR2A - - View
C6orf199 - - View
CCNDBP1 - This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune … View
PERQ1 - - View
NME1 - NME1 was identified because of its reduced mRNA transcript levels in highly metastatic cells. NME1 encodes the 'A' isoform of … View
C19orf21 - - View
LSM6 - Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; … View
SLC22A9 - - View
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SKP1A - This gene encodes an F-box protein which functions as a substrate recognition component of the SCF ubiquitin ligase complex. It … View
ETV4 - Transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5'[AC]GGA[AT]GT-3'. View
KCNE1L - Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their … View
ARSE - Arylsulfatase E is a member of the sulfatase family. ARSE is glycosylated postranslationally and localized to the golgi apparatus. Sulfatases … View
LIMS1 - The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The … View
ANK3 - Ankyrins are a family of proteins that are believed to link the integral membrane proteins to the underlying spectrin-actin cytoskeleton … View
C6orf83 - - View
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C21orf104 - - View
NUP43 - Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. … View
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RCN1 - Reticulocalbin 1 is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with … View
NMUR2 - - View
PSMD14 - POH1 (pad one homolog-1) is a component of the 26S proteasome, a multiprotein complex that degrades proteins targeted for destruction … View
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RASGEF1A - - View
FLT4 - - View
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RRM2 - Ribonucleotide reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. It is composed of 2 non-identical subunits, proteins M1 and M2. … View
ITGA10 - Integrins are integral membrane proteins composed of an alpha chain and a beta chain, and are known to participate in … View
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MLLT6 - - View
TRIM48 - - View
FGFBP1 - FGFBP1, or HBP17, binds to both acidic (FGF1; MIM 131220) and basic (FGF2; MIM 134920) fibroblast growth factors in a … View
ING5 - The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit … View
LSM3 - Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; … View
HLA-DPB2 - - View
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ACHE - Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also … View
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COPB2 - The Golgi coatomer complex (see MIM 601924) constitutes the coat of nonclathrin-coated vesicles and is essential for Golgi budding and … View
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CPXCR1 - - View
GALE - This gene encodes UDP-galactose-4-epimerase which catalyzes 2 distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization … View
SPATA3 - - View
EVI5L - - View
WDR51A - - View
SFRS15 - May act to physically and functionally link transcription and pre-mRNA processing (By similarity). View
BCKDHB - Branched-chain keto acid dehydrogenase is a multienzyme complex associated with the inner membrane of mitochondria, and functions in the catabolism … View
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SSR2 - The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER … View
IRAK3 - Inhibits dissociation of IRAK1 and IRAK4 from the Toll- like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 … View
PDCD8 - This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space … View
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RANBP1 - Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP … View
CCL4 - Monokine with inflammatory and chemokinetic properties. Binds to CCR5 and to CCR8. One of the major HIV-suppressive factors produced by … View