| RGD620382 |
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This probe is non-specific and may hybridize to multiple genes. GeneID:136100/Nucleoside 2-deoxyribosyltransferase domain containing protein RGD620382; GeneID:217086/putative c-Myc-responsive (DBSS_moderate)
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| PTPRN |
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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to …
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| BCL6 |
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The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein …
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| MYH15 |
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| - |
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| - |
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| NPPC |
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Natriuretic peptides comprise a family of 3 structurally related molecules: atrial natriuretic peptide (ANP; MIM 108780), brain natriuretic peptide (BNP; …
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| - |
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Members of the immunoglobulin superfamily are found in hundreds of proteins of different functions. Immunoglobulin-like domains may be involved in …
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| - |
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| PCDHB18 |
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| KIRREL2 |
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| Ece1 |
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catalyzes the conversion of the big endothelin precursor (big ET-1) to the vasoconstrictive peptide endothelin [RGD]
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| Bcam |
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may act as an adhesion molecule and receptor for laminin [RGD]
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| RAB7 |
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Members of the RAB family of RAS-related GTP-binding proteins are important regulators of vesicular transport and are located in specific …
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| PTGER4 |
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The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of …
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| - |
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| - |
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| PAQR4 |
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| DVL3 |
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This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The …
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| AQP3 |
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Aquaporin 3 is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major …
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| - |
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| ZMYND15 |
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| TJP4 |
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| ZNF682 |
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| ZBTB2 |
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May be involved in transcriptional regulation.
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| C20orf30 |
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| - |
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| ORMDL3 |
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| GPD2 |
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| Tgfb3 |
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involved in epithelial and endothelial cell proliferation and differentiation during development [RGD]
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| ID1 |
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The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic …
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| BMX |
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Tyrosine kinases are either receptor molecules, which contain transmembrane and extracellular domains, or nonreceptor proteins, which are located intracellularly. One …
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| SYT3 |
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May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may …
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| CD151 |
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The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. …
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| LYN |
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| PAG1 |
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The protein encoded by this gene is a type III transmembrane adaptor protein that binds to the tyrosine kinase csk …
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| UCN |
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This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) …
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| Hsd17b7 |
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a phosphoprotein that associates with the short form of the prolactin receptor [RGD]
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| Gpc1 |
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glycosylphosphatidylinositol-linked heparan sulfate proteoglycan that may play a role in cell adhesion and growth factor response in the nervous system …
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| NR2E3 |
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This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have …
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| BRPF3 |
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| SUV420H2 |
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| FOXI1 |
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This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific …
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| TACC2 |
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Transforming acidic coiled-coil proteins are a conserved family of centrosome- and microtubule-interacting proteins that are implicated in cancer. This gene …
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| NRBP2 |
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| TPH1 |
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Tryptophan hydroxylase (TPH; EC 1.14.16.4) catalyzes the biopterin-dependent monooxygenation of tryptophan to 5-hydroxytryptophan (5HT), which is subsequently decarboxylated to form …
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| SETMAR |
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| TM7SF2 |
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Involved in the conversion of lanosterol to cholesterol.
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| SH3YL1 |
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| C21orf94 |
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| C2orf24 |
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| - |
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The specific function of the adaptor protein encoded by this gene is not known; however, it is speculated that it …
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| BBOX1 |
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This gene encodes gamma butyrobetaine hydroxylase which catalyzes the formation of L-carnitine from gamma-butyrobetaine, the last step in the L-carnitine …
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| PRX |
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The PRX gene encodes L- and S-periaxin, proteins of myelinating Schwann cells, and is mutated in Dejerine-Sottas syndrome (MIM 145900) …
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| GPR103 |
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G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM]
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| USP7 |
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Cleaves ubiquitin fusion protein substrates. Binds to the herpes virus protein VMW110 which may therefore modulate its substrate specificity or …
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| CTCFL |
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CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. …
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| PIGS |
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This gene encodes a protein that is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on …
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| - |
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| - |
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| WARS2 |
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Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino …
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| USP31 |
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| TIMP1 |
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This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the …
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| Cntf |
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a cytokine involved in neuronal degeneration and adipocyte gene expression [RGD]
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| Sod1 |
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catalyzes the conversion of superoxide to hydrogen peroxide and molecular oxygen; involved in response to oxidative stress [RGD]
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| Egf |
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binds the epidermal growth factor receptor; may play a role in MAP kinase mediated signaling pathways [RGD]
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| Slc16a1 |
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transports lactic acid and other monocarboxylic acids [RGD]
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| Dut |
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precursor of thymidine nucleotides; may inhibit peroxisome proliferator-activated receptor (PPAR) activity [RGD]
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| Gtf2b |
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putative subunit of RNA polymerase II [RGD]
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| Cdk4 |
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positive regulator of the cell cycle; plays a role in cell cycle progression [RGD]
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| Igf1 |
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growth factor; plays a major role in mammalian growth [RGD]
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| Gab2 |
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adapter for transmitting various signals in response to stimuli through cytokine and growth factor receptors [RGD]
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| Zfp148 |
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Kruppel-like zinc finger protein 148 is a transcription factor; regulates the transcription of genes such as gastrin, beta enolase, and …
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| Lbr |
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nuclear localization signal (NLS) binding protein [RGD]
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| Gprk5 |
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plays a role in homologous desentization of the thyrotropin receptor [RGD]
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| Hrsp12 |
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involved in response to heat shock [RGD]
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| Mvk |
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kinase that catalyzes the ATP-dependent phosphorylation of mevalonic acid to form mevalonate 5-phosphate; involved in the cholesterol biosynthetic pathway [RGD]
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| Igbp1 |
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human homolog is a regulatory subunit of protein phosphatase 2-type phosphatases [RGD]
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| Tcp1 |
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facilitates alpha- and beta-tubulin folding and remodelling of the microtubule cytoskeleton during spermiogenesis; may play a role in heterochromatin remodelling …
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| Gnb1 |
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component of heterotrimeric G-proteins; mediates activity of effector molecules and contributes to the specificity of G-proteinreceptor interaction; mat confer preferential …
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| Ripk3 |
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mouse homolog is a RIP kinase family member involved in cell signal transduction [RGD]
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| Lamc1 |
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an extracellular matrix protein [RGD]
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| Sc4mol |
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may be involved in the repair process of nerve tissues [RGD]
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| P2rx4 |
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ATP-activated ionotropic receptor; involved in synaptic transmission in the central nervous system [RGD]
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| Masp2 |
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member of the MBL/MASPs/Map19 complex of the mannan binding lectin pathway of complement activation; catalyzes the cleavage of complement component …
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| Olr1504 |
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This probe is non-specific and may hybridize to multiple genes. GeneID:134784/olfactory receptor 1500; GeneID:170408/olfactory receptor 1504
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| Rax |
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may play a role in glial cell development [RGD]
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| Vdac1 |
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large diameter (2.53 nm) channel, permeable to ions and small molecules; molecular component of Ca2+ transport across the mitochondrial membranes …
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| Pdx1 |
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plays a role in beta cell differentiation [RGD]
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| Tmf1 |
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human homolog interacts with the androgen receptor and may act as a coactivator [RGD]
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| Slc5a2 |
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a Na(+)-coupled glucose transporter involved in reabsorption of filtered glucose in the kidney [RGD]
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| Tuba1 |
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forms heterodimers with beta-tubulin; acts as a structural component of the microtubule cytoskeleton; plays a role in microtubule-based processes [RGD]
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| Dd5 |
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may be involved in sexual maturation [RGD]
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| Fcgr3 |
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This probe is non-specific and may hybridize to multiple genes. GeneID:133283/Fc gamma receptor II beta; GeneID:135569/Fc gamma receptor II beta
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| Acsl3 |
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catalyzes initial reaction of fatty acid metabolism to produce Acyl-CoA; plays a key role in lipid metabolism; may mediate the …
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| Ptgfr |
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receptor for prostaglandin F2; activation induces signaling via increased intracellular calcium [RGD]
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| Cdc5l |
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prolactin-responsive gene; may be involved with pre-mRNA splicing [RGD]
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| Txn2 |
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involved in dithiol reducing [RGD]
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| Cav3 |
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regulates basal GTPase activity of purified heterotrimeric G-proteins and binds to and regulates the activity of endothelial nitric oxide synthase …
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| Alcam |
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human homolog is a cell adhesion molecule; involved in bone morphogenesis [RGD]
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| Af6 |
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debrisoquine 4-hydroxylase [RGD]
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| Slc29a1 |
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nucleoside transporter [RGD]
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| Grn |
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plays a role in regulation of epithelial cell growth [RGD]
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| Crry |
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membrane-bound inhibitor of complement activation; may play a role in tumor immune surveillance; exists as two different isoforms in all …
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| Pafah1b1 |
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subunit of the brain intracellular platelet-activating factor acetylhydrolase, which is composed of alpha1, alpha2, and beta subunits [RGD]
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| Mta1 |
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high expression of this protein correlates with the metastatic potential of cells; may have a role in gene regulation [RGD]
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| Map2k1 |
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kinase that activates Mapk3 (Erk1) and Mapk1 (Erk2) kinases [RGD]
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| Tsc2 |
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acts as a tumor suppressor; may play a role in cell cycle regulation; acute phase response, and negative regulation of …
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| Ahcy |
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enzyme that catalyzes the hydrolysis of S-adenosylhomocysteine to form adenosine and homocysteine [RGD]
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| - |
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| - |
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| Cpt1b |
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malonyl-CoA-insensitive form found in red muscle [RGD]
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| Ela1 |
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catalyzes the hydrolysis of elastin and other proteins [RGD]
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| Cebpe |
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basic region/leucine zipper transcriptional activator; may mediate cytokine gene expression in mature cells; may play a role in macrophage development …
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| Amph1 |
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activates dynamin GTPase activity; may play a role in clatherin mediated endocytosis in synaptic vesicles [RGD]
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| Rab5a |
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low molecular weight GTP binding protein; may play a role in regulation of vesicular transport [RGD]
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| Htr1a |
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regulates AMPA receptor channels in the prefrontal cortex; regulation is mediated via inhibition of Ca2+/calmodulin-dependent kinase II [RGD]
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| Il8ra |
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G-protein coupled receptor for interleukin 8 [RGD]
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| Sp1 |
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transcription factor that recognizes 5'-CCGCCC promoter sequence; plays a role in transcriptional regulation of many genes [RGD]
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| Tbxa2r |
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binds thromboxane and induces an increase in cytosolic Ca2+ levels; may play a role renal electrolyte metabolism; may mediate vascular …
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| Grm6 |
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has adenylate cyclase inhibiting metabotropic glutamate receptor activity; may play a role in synaptic transmission between photoreceptor cells and ON-bipolar …
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| Chrna1 |
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alpha subunit of the AChR gamma and AChR epsilon acetylcholine receptor subtypes [RGD]
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| Usf2 |
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ubiquitous transcription factor; may play a role in hormonal and dietary regulations [RGD]
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| Hspd1 |
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a stress-inducible molecular chaperone which participates in protein folding [RGD]
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| Pla2g6 |
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has Ca2+ independent phospholipase A2 activity; may play a role in regulating transmembrane ionic fluxes in pancreatic beta cells [RGD]
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| Gnai3 |
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has GTPase activity; involved in zymogen granule-plasma membrane fusion in pancreatic cells [RGD]
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| Pthr1 |
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binds parathyroid hormone (PTH) and parathyroid hormone-related peptide (PTHrP); induces both adenylate cyclase and phospholipase C signaling; involved in mineral …
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| Hsf2 |
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DNA binding protein; involved in the transcriptional regulation of heat shock protein (hsp) genes [RGD]
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| Ccl22 |
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chemoattractant for dendritic cells, natural killer (NK) cells, and the Th2 subset of peripheral blood T cells [RGD]
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| Prkab2 |
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a component of the AMPK alpha2beta2gamma1 complex which phosphorylates glycogen synthase [RGD]
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| Apoa5 |
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member of the apolipoprotein family; expression increases during liver regeneration [RGD]
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| Rab6a |
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GTP binding protein that facilitates ATPase activity of N-ethylmaleimide-sensitive fusion protein (NSF) to signal vesicle fusion [RGD]
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| Bche |
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esterase; enzyme not involved in bladder contractility [RGD]
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| Jwa |
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vitamin A responsive gene; interacts with Excitatory amino-acid carrier 1 (EAAC1) to regulate function [RGD]
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| Kcnk9 |
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an acid-sensing K(+) channel; highly sensitive to changes in extracellular pH [RGD]
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| Dffa |
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inhibitor of DFF40/CAD and caspase-dependent apoptotic DNA fragmentation [RGD]
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| Mk1 |
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potassium channel; member of the Shaker subfamily; may play a role in myelination of Schwann cells in peripheral nerves [RGD]
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| Gja6 |
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component of gap junctions; may regulate gap junction assembly [RGD]
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| Serpinb2 |
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plays a role in proteolytic degradation of extracellular matrices in tissue remodeling; mediates the entire process of periodontal wound healing …
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| Adam2 |
- |
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may play a role in sperm-oocyte binding and fusion [RGD]
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| Lyn |
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Src-related tyrosine kinase; may play a role in trophoblast giant cell differentiation [RGD]
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| Stx17 |
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member of the syntaxin family; may be involved in membrane trafficking [RGD]
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| Crx |
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an OTX-like homeobox protein; may play an important role in the retina [RGD]
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| Clock |
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member of the basic helix-loop-helix (bHLH) family of transcription factors; involved in light dependent signal transduction of the circadian clock …
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| Kcna5 |
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voltage gated potassium channel; functions as a delayed rectifier-like K+ channel [RGD]
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| Chrm5 |
- |
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M5 muscarinic receptor; stimulates phosphoinositide hydrolysis without affecting adenylyl cyclase activity [RGD]
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| Rasa1 |
- |
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may play a role in Ras GTPase mediated signal transduction; may be involved in cell proliferation and cell migration [RGD]
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| Asgr1 |
- |
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acts as a hepatic glycoprotein receptor [RGD]
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| Gnb3 |
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G-protein beta subunit expressed primarily in heart and also in brain [RGD]
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| Clcn4-2 |
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may act as a chloride channel [RGD]
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| Rab3a |
- |
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regulated synaptic vesicle endocytosis [RGD]
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| Zfp260 |
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human homolog is overexpressed in colorectal cancer, altered expression may occur at an early stage in tumor progression [RGD]
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| Epha8 |
- |
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may act as a receptor protein tyrosine kinase [RGD]
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| Kcnn1 |
- |
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voltage independent potassium channel; activated by intracellular calcium [RGD]
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| Smo |
- |
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may act as a signaling component of the Patched (Ptch) signaling pathway [RGD]
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| Gtf2a1 |
- |
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large subunit of transcription factor 2a; human homolog interacts with the TATA-binding protein to act early during preinitiation complex formation …
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| Ppp2r2b |
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may regulate the activity of protein phosphatase 2A catalytic subunit; may play a role in spermatid elongation [RGD]
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| Lep |
- |
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involved in regulation of body weight; may have a role in angiogenesis [RGD]
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| Plod1 |
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catalyzes the hydroxylation of lysine residues in procollagen to form hydroxylysine [RGD]
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| SLC7A13 |
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| Gjb3 |
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component of gap junctions; mutation of human gene associated with high-frequency hearing loss and human erythrokeratodermia variabilis, a skin disorder …
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| Ppia |
- |
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may play a role in protein folding or intracellular protein transport [RGD]
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| Rpl35a |
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ribosomal protein that binds tRNA [RGD]
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| Trp63 |
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a keratinocyte transcription factor; has possible roles in development and differentiation [RGD]
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| Rbbp7 |
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mouse homolog interacts with histone deacetylases and is a component of several co-repressor complexes [RGD]
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| Ephx1 |
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catalyzes the hydration of a wide range of xenobiotic arene oxides [RGD]
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| Tmlhe |
- |
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first enzyme in the carnitine biosynthesis pathway; plays an important role in the transport of fatty acids across the inner …
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| Neu1 |
- |
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enzyme that cleaves sialic acid from glycoproteins and glycolipids [RGD]
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| Bad |
- |
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may be involved in induction of programmed cell death [RGD]
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| Gsk3a |
- |
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protein-serine kinase; may mediate hormonal control of several regulatory proteins including glycogen synthase and the transcription factor c-jun [RGD]
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| Ifrd1 |
- |
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may have a role in signal transduction; necessary for muscle differentiation [RGD]
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| Pscd2 |
- |
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may play a role in transport from the Golgi apparatus to secretory vesicles [RGD]
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| Cd164 |
- |
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membrane protein found in lysosomal and endosomal compartments [RGD]
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| Accn2 |
- |
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forms a proton-gated ion channel that may play a role in sensory neuron function and pain perception [RGD]
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| Ppm1a |
- |
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protein phosphatase; monomeric enzyme that dephosphorylates phospho-proteins [RGD]
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| Tceb3 |
- |
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subunit A of the transcription factor B (SIII) complex (also known as elongin); frees RNA Polymerase II from transient pausing …
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| SMCX |
- |
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-
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| Nrg1 |
- |
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ligand for Erbb3 and Erbb4 receptors; gene produces many different alternative splicing isoforms; involved in neural and organ development [RGD]
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| Strn |
- |
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calmodulin-binding protein that may be involved in neuronal excitatory calcium-signaling pathways [RGD]
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| Sdfr1 |
- |
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synaptic membrane glycoprotein that is a member of the immunoglobulin (Ig) superfamily [RGD]
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| Acpp |
- |
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may catalyze the hydrolysis of an orthophosphoric monoester to form an alcohol and phosphate in prostatic fluid [RGD]
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| Chrna5 |
- |
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neuronal receptor and ion channel activated by acetylcholine; mediates release of catecholamines into bloodstream [RGD]
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| Tgfb1 |
- |
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binds the TGFbeta receptor; plays a role in regulation of cell growth and proliferation; induces synthesis of extracellular matrix proteins …
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| Lamp1 |
- |
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This probe is non-specific and may hybridize to multiple genes. GeneID:134168/lysosomal membrane glycoprotein 1; GeneID:169074/ESTs
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| Col4a1 |
- |
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This probe is non-specific and may hybridize to multiple genes. GeneID:134252/procollagen, type IV, alpha 1; GeneID:167959/fatty acid binding protein 5, …
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| Tcam1 |
- |
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interacts with growth hormone and BAF60b during gene coding [RGD]
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| Sema4f |
- |
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has axon growth-cone collapse activity [RGD]
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| Akap12 |
- |
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tumor suppressor protein that acts as a scaffolding protein and is involved in mitogen-induced cytoskeletal reorganization; binds to and is …
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| Erbb4 |
- |
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binds neuregulins; involved in epithelial-mesenchymal interactions during development; may play a role in tooth morphogenesis [RGD]
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| Ereg |
- |
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may play a role in vascular smooth muscle cell proliferation and vascular remodeling stimulated by vasoactive agonists [RGD]
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| Ppp3r1 |
- |
|
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regulatory subunit of the enzyme that catalyzes the calcium-dependent removal of serine- and threonine-bound phosphate groups [RGD]
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| Neud4 |
- |
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neurospecific gene that is developmentally regulated [RGD]
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| Slc16a3 |
- |
|
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monocarboxylate transporter; mediates efflux of glycolytically derived lactic acid from white skeletal muscle [RGD]
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| Kcnab1 |
- |
|
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beta subunit of potassium channel involved in alteration of channel activation kinetics [RGD]
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| Gpr6 |
- |
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may mediate later differentiation events within the superficial cortical layers during cerebral cortical development [RGD]
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| DNAJB7 |
- |
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Probably acts as a co-chaperone (By similarity).
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| Cyp2a1 |
- |
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has testosterone 7 alpha-hydroxylase activity; also catalyzes 3,4 epoxidation of coumarin in coumarin metabolism [RGD]
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| Slc6a9 |
- |
|
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transporter for glycine which is dependent on external Na+ and Cl- and may be involved in inhibitory glycinergic transmission [RGD]
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| Pcsk3 |
- |
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enzyme; involved in the proteolytic processing of extracellular superoxide dismutase (EC-SOD) [RGD]
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| Zfp99 |
- |
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zinc-finger protein; may act as a transcriptional repressor [RGD]
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