| USP10 |
- |
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|
Ubiquitin specific protease are required to remove ubiquitin from specific proteins or peptides to which ubiquitin is attached.
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| - |
- |
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-
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| - |
- |
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-
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| KIAA1712 |
- |
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-
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| - |
- |
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-
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| KRT25A |
- |
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-
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| RBM5 |
- |
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-
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| - |
- |
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-
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| HCG2P7 |
- |
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-
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| MULK |
- |
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-
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| PDLIM1 |
- |
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-
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| RFNG |
- |
|
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Glycosyltransferase that initiates the elongation of O- linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch …
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| RAD18 |
- |
|
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The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions …
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| Esr1 |
- |
|
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acts as a transcriptional activator when bound to estrogen; may play a role in myocardial regulation [RGD]
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| CCR4 |
- |
|
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The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC …
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| BRUNOL5 |
- |
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-
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| HEMGN |
- |
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-
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| GPR7 |
- |
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-
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| ALAS1 |
- |
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-
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| PARVG |
- |
|
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Members of the parvin family, including PARVG, are actin-binding proteins associated with focal contacts.[supplied by OMIM]
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| - |
- |
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-
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| HSPB1 |
- |
|
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Involved in stress resistance and actin organization.
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| C10orf30 |
- |
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-
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| FTS |
- |
|
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The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die …
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| C16orf28 |
- |
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-
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| HOXA11 |
- |
|
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In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, …
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| - |
- |
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-
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| TFAP4 |
- |
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Transcription factor that activates both viral and cellular genes by binding to the symmetrical DNA sequence 5'- CAGCTG-3'.
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| Anxa6 |
- |
|
|
Ca(2+)-sensitive phospholipid-binding protein that binds CRHSP-28 [RGD]
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| CD59 |
- |
|
|
Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of …
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| - |
- |
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-
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| ALDH3A1 |
- |
|
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Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in …
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| KCNH8 |
- |
|
|
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their …
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| Crhr1 |
- |
|
|
receptor that binds corticotropin-releasing hormone; involved in regulation of the hypothalamic-pituitary-adrenal cortical axis [RGD]
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| Slc15a1 |
- |
|
|
acts as a proton dependent peptide transporter; may transport oral beta-lactam antibiotics across intestinal brush borders [RGD]
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| Dpysl4 |
- |
|
|
protein that may regulate neuronal plasticity by transducing signals from semaphorins [RGD]
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| Sdc3 |
- |
|
|
mediates adhesion of Schwann cells to alpha4 type (V) collagen [RGD]
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| Akt3 |
- |
|
|
kinase that associates with both protein kinase C subspecies and beta gamma subunits of G proteins [RGD]
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| P2rx7 |
- |
|
|
an ATP receptor; may be involved in fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells [RGD]
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| Slc12a5 |
- |
|
|
neuronal specific potassium-chloride cotransporter isoform; may play a role in response to neuronal injury [RGD]
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| RUTBC3 |
- |
|
|
-
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| - |
- |
|
|
RDHE2 belongs to a family of short-chain alcohol dehydrogenases/reductases that catalyze the first and rate-limiting step that generates retinaldehyde from …
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| Psmc1 |
- |
|
|
may play a role in ATP-dependent RNA/DNA unwinding [RGD]
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| Slc6a13 |
- |
|
|
high-affinity gamma-aminobutyric acid (GABA) transporter; terminates biological actions of GABA by reuptake into cell; reuptake function utilizes sodium and chloride …
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| Nos1 |
- |
|
|
enzyme that catalyzes the production of nitric oxide [RGD]
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| Kynu |
- |
|
|
enzyme involved in the biosynthesis of NAD cofactors from tryptophan [RGD]
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| Eif2b3 |
- |
|
|
guanine nucleotide exchange factor that regulates key step in protein synthesis; restores eIF2 to its active GTP-bound state [RGD]
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| CSPG6 |
- |
|
|
This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either …
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| Cxcl10 |
- |
|
|
induces DNA synthesis, cell proliferation, and cell migration in vascular smooth muscle cells; may play a role in vascular remodeling …
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| Hsd17b1 |
- |
|
|
catalyzes the conversion between 17 beta-hydroxy- and 17-ketosteroids; plays a role in estradiol biosynthesis [RGD]
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| Cdipt |
- |
|
|
catalyzes the formation of phosphatidylinositol and CMP from CDP-diacylglycerol and myo-inositol [RGD]
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| DRD5 |
- |
|
|
This gene encodes the D5 subtype of the dopamine receptor. The D5 subtype is a G-protein coupled receptor which stimulates …
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| - |
- |
|
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-
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| PDZK1 |
- |
|
|
-
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| STOML1 |
- |
|
|
-
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| CNTN3 |
- |
|
|
Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity (By similarity).
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| Glra2 |
- |
|
|
glycine gated chloride channel; displays strychnine-sensitive ion channel activity; may play a role in synaptogenesis [RGD]
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| Cspg4 |
- |
|
|
extracellular matrix protein secreted by many cell types; member of the large chondroitin sulfate proteoglycan (CSPG) family; may be involved …
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| Oas1 |
- |
|
|
This probe is non-specific and may hybridize to multiple genes. GeneID:127767/2 ' -5 ' oligoadenylate synthetase 1I; GeneID:171043/2 ' -5 …
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| Cnga2 |
- |
|
|
cyclic nucleotide-gated ion channel involved in signal transduction; may participate in neural communication and plasticity [RGD]
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| Cdh6 |
- |
|
|
may mediate calcium dependent cell adhesion; may play a role in ovarian development [RGD]
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| Pax8 |
- |
|
|
acts as a redox regulated transcriptional activator [RGD]
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| SP110 |
- |
|
|
The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene …
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| Phkg1 |
- |
|
|
catalytic subunit of phosphorylase kinase complex; plays a role in glycogen metabolism [RGD]
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| Kcnj12 |
- |
|
|
inward rectifier potassium channel [RGD]
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| Nudc |
- |
|
|
expression is induced by prolactin; highest expression occurs during the G1/S transition phase of the cell cycle [RGD]
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| Msx2 |
- |
|
|
homeobox transcription factor [RGD]
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| Mat1a |
- |
|
|
enzyme that catalyzes the formation of S-adenosylmethionine [RGD]
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| Atp1a2 |
- |
|
|
catalytic subunit of the membrane ATPase; involved in ATP dependent transport of Na+ and K+; necessary for creating and maintaining …
|
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| MT1X |
- |
|
|
Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both …
|
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| Sncg |
- |
|
|
may play a role in the neurofilament network [RGD]
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| Foxa1 |
- |
|
|
may act as a transcription factor for hepatocyte specific gene expression [RGD]
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| Lalba |
- |
|
|
regulatory subunit of lactose synthase found in milk; involved in altering substrate specificity of galactosyltransferase [RGD]
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| Lcat |
- |
|
|
enzyme involved in the metabolism of plasma lipoproteins [RGD]
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| Nr2c2 |
- |
|
|
member of the nuclear receptor subfamily 2; involved in stress response pathway; potentially involved in neuronal differentiation [RGD]
|
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| Ascl2 |
- |
|
|
may play a role in neural crest cell development and neuronal determination [RGD]
|
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| Sod2 |
- |
|
|
manganese superoxide dismutase; intramitochondrial free radical scavenging enzyme [RGD]
|
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| Cyp3a13 |
- |
|
|
catalyzes the hydroxylation of progesterone at 6beta, 16alpha, and 21 positions [RGD]
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| Abcc1 |
- |
|
|
ATP-binding cassette (ABC) multiple drug resistance protein involved in the release of glutathione synthase during oxidative stress [RGD]
|
View
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| Ptgis |
- |
|
|
catalyzes the conversion of prostaglandin H2 to prostacyclin in prostaglandin biosynthesis [RGD]
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|
| Slc8a2 |
- |
|
|
isoform 2 of sodium/calcium exchanger; regulates intracellular calcium levels and maintains calcium homeostasis; may be important for the control of …
|
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|
| Pou3f1 |
- |
|
|
may act as a transcriptional regulator of gene expression during Schwann cell differentiation and myelination [RGD]
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| APH1B |
- |
|
|
APH1 is a multipass transmembrane protein that interacts with presenilin (see PSEN1; MIM 104311) and nicastrin (APH2; MIM 605254) as …
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| TTYH3 |
- |
|
|
This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. …
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| Abcc2 |
- |
|
|
multispecific organic anion transporter; mutation may be responsible for conjugated hyperbilirubinemia in the TR- rat, which is a model for …
|
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| Rere |
- |
|
|
atrophin-1 related protein found enriched in cerebellum and testis [RGD]
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| Ptprj |
- |
|
|
protein tyrosine phosphatase expressed in smooth muscle cells; may be involved in cell adhesion or cell-cell signaling [RGD]
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| Ucp1 |
- |
|
|
plays a role in heat production by uncoupling oxidative phosphorylation from the respiratory chain [RGD]
|
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| E2f5 |
- |
|
|
transcription factor implicated in the regulation of genes associated with cell cycle progression [RGD]
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|
| Mvd |
- |
|
|
enzyme that catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate; involved in cholesterol biosynthesis [RGD]
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| Tdo2 |
- |
|
|
rate-limiting enzyme in the catabolism of tryptophan [RGD]
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| Lrpap1 |
- |
|
|
predicted to act as a low density lipoprotein receptor associated protein [RGD]
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| Htr2a |
- |
|
|
a receptor for 5-hydroxytryptamine (serotonin); activates phospholipase C signaling pathway; involved in promoting cellular transformation [RGD]
|
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|
| Adra2b |
- |
|
|
regulates neurotransmitter release from adrenergic neurons; member of the G protein-coupled receptor superfamily; highly homologous with alpha2A and alpha2C subtypes …
|
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|
| Kcna2 |
- |
|
|
delayed-rectifier K+ channel expressed in heart and brain [RGD]
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| Pgr |
- |
|
|
receptor for progesterone; regulates glutamic acid decarboxylase expression in the hypothalamus during proestrus; may mediate production of the GnRH and …
|
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| Dmd |
- |
|
|
a vital component of a muscle sarcolemma membrane-spanning complex that connects cytoskeleton to basal lamina; plays a role in retinal …
|
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| Apoa1 |
- |
|
|
major component of high density lipoprotein (HDL) that is involved in intercellular cholesterol transport in astrocytes; cofactor for lecithin cholesterolacyltransferase …
|
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|
| Gjb4 |
- |
|
|
component of gap junctions; mutations of human gene associated with erythorokeratoderma variabilis [RGD]
|
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|
| Cyp1a1 |
- |
|
|
monooxygenase that plays a role in dioxin metabolism and detoxification which is 3-methylcholanthrene-inducible [RGD]
|
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| Drd3 |
- |
|
|
may be involved in facilitating the effects of antipsychotic drugs and drug treatments for Parkinson's disease [RGD]
|
View
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| Sod3 |
- |
|
|
This probe is non-specific and may hybridize to multiple genes. GeneID:127748/superoxide dismutase 3, extracellular; GeneID:170992/Superoxide dismutase 3
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| Scnn1g |
- |
|
|
acts as an epithelial sodium ion channel; regulates salt and fluid transport in the kidney [RGD]
|
View
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| Ptger3 |
- |
|
|
receptor that binds prostaglandins E2 and E1; may be involved in natriuresis [RGD]
|
View
|
| Gabrg1 |
- |
|
|
gamma 1 subunit of GABA A receptor; may be involved in mediating the potentiation of GABA evoked currents by benzodiazepines …
|
View
|
| Gabra5 |
- |
|
|
subunit of the GABAA receptor; may be part of distinct GABAA receptors within the olfactory bulb [RGD]
|
View
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| Mx1 |
- |
|
|
mouse homolog is an interferon inducible gene that confers influenza resistance to mice [RGD]
|
View
|
| L1cam |
- |
|
|
neural cell adhesion molecule expressed in brain; isoform L1cs is a likely alternative splice variant expressed in the peripheral nervous …
|
View
|
| PCAF |
- |
|
|
CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including …
|
View
|
| Rab11a |
- |
|
|
GTP-binding protein [RGD]
|
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|
| Pla2g4a |
- |
|
|
catalyzes the synthesis of COX-2 substrate arachidonic acid (AA); may play a role in epileptogenesis [RGD]
|
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| Amhr2 |
- |
|
|
receptor that binds Mullerian inhibiting substance; involved in testis and ovary function [RGD]
|
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|
| Grin3a |
- |
|
|
glutamate receptor subunit involved in neuronal signaling [RGD]
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|
| Mal |
- |
|
|
hydrophobic protein; may have an important role in compact myelin [RGD]
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|
| Lsamp |
- |
|
|
immunoglobulin (Ig) superfamily member; may act as a recognition molecule for the formation of neuronal connections [RGD]
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| Epha7 |
- |
|
|
receptor for members of the ephrin-A subfamily of receptor tyrosine kinases; binds with ephrin-A1, -A2, -A3, -A4 and -A5, may …
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|
| SLC7A1 |
- |
|
|
High-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues. …
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| Cma1 |
- |
|
|
connective tissue mast cell protein with proteolytic activity; may facilitate apoptosis [RGD]
|
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|
| Cckar |
- |
|
|
G-protein coupled receptor activated by cholecystokinin; may be involved in food intake and insulin regulation [RGD]
|
View
|
| Kcnj6 |
- |
|
|
inwardly-rectifying potassium channel [RGD]
|
View
|
| Lenep |
- |
|
|
lens epithelial cell gene; may be involved in lens epithelial cell differentiation [RGD]
|
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|
| Dlgh3 |
- |
|
|
human homolog is a protein with guanylate kinase activity; involved in synaptogenesis and cell proliferation [RGD]
|
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|
| Flt1 |
- |
|
|
tyrosine kinase receptor for vascular endothelial growth factor; may play a role in cell proliferation and cell survival [RGD]
|
View
|
| Scn10a |
- |
|
|
voltage-gated sodium channel that is resistant to tetrodotoxin [RGD]
|
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|
| Stat3 |
- |
|
|
transcription factor that plays a role in induction of gene expression during acute phase response [RGD]
|
View
|
| Cyb5b |
- |
|
|
a cytochrome with isoforms located in endoplasmic reticulum and mitochondrial outer membranes [RGD]
|
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|
| - |
- |
|
|
-
|
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|
| Crem |
- |
|
|
transcription factor that is involved in regulation of cAMP-induced gene transcription; exists in multiple alternatively spliced isoforms that regulate gene …
|
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|
| C9 |
- |
|
|
component of the terminal complement complex C5b-9; may be involved in inducing cleavage and activation of caspase 3 and mediating …
|
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|
| P2rx5 |
- |
|
|
an ATP-gated ion channel [RGD]
|
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|
| Ggh |
- |
|
|
catalyzes the removal of glutamate residues [RGD]
|
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|
| Ptger2 |
- |
|
|
binds prostaglandin E2 and induces increased cAMP; may play a role in skeletal growth [RGD]
|
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|
| C1orf48 |
- |
|
|
Part of the MIS12 complex, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis.
|
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|
| - |
- |
|
|
-
|
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|
| CARD15 |
- |
|
|
This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and …
|
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|
| ZNF75A |
- |
|
|
-
|
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| - |
- |
|
|
-
|
View
|
| PRRG3 |
- |
|
|
-
|
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|
| ANXA11 |
- |
|
|
This gene encodes a member of the annexin family, a group of calcium-dependent phospholipid-binding proteins. Annexins have unique N-terminal domains …
|
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|
| - |
- |
|
|
-
|
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|
| Abcb4 |
- |
|
|
energy-dependent efflux pump; may be involved in changes in bile formation in response to diabetes [RGD]
|
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|
| Pou2f3 |
- |
|
|
may play a role in epidermal development; variant Skn-1i inhibits Oct1 transactivation; variant Skn1a activates cytokeratin 10 (K10) gene expression …
|
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|
| Pou3f3 |
- |
|
|
acts as a transcriptional activator in oligodendrocytes; may play a role in regulation of neural development [RGD]
|
View
|
| Prss1 |
- |
|
|
catalyzes the cleavage of Arg-Xaa, Lys-Xaa [RGD]
|
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|
| Olr287 |
- |
|
|
member of the olfactory receptor family [RGD]
|
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|
| Pap |
- |
|
|
lectin-related secretory protein; may be involved in stress response to control bacterial proliferation during acute pancreatitis [RGD]
|
View
|
| Pspn |
- |
|
|
promotes survival of ventral midbrain dopaminergic neurons and motor neurons; may mediate increase in dopamine-dependent behavioral parameters [RGD]
|
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|
| Kcnj1 |
- |
|
|
inwardly-rectifying potassium channel that binds to CTFR to mediate potassium transport; mediates potassium transport into urine [RGD]
|
View
|
| Kcna3 |
- |
|
|
encodes a lymphocyte potassium channel [RGD]
|
View
|
| Abat |
- |
|
|
main component of the 4-aminobutyrate (GABA) shunt; major inhibitory neurotransmitter [RGD]
|
View
|
| Htr4 |
- |
|
|
receptor for serotonin; may play a role in cognition and anxiolysis [RGD]
|
View
|
| Nab1 |
- |
|
|
transcriptional repressor and an immediate-early gene [RGD]
|
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|
| Dmbt1 |
- |
|
|
putative scavenger receptor; may be involved in liver repair and differentiation [RGD]
|
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|
| Glra1 |
- |
|
|
glycine receptor strychnine binding subunit; generates glycine gated strychnine sensitive chloride current in the central nervous system [RGD]
|
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|
| Mor1 |
- |
|
|
catalyzes the conversion of pyruvate or oxaloacetate to malate [RGD]
|
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|
| Pfkfb1 |
- |
|
|
bifunctional enzyme; catalyzes synthesis and degradation of fructose 2,6-bisphosphate, a ubiquitous stimulator of glycolysis [RGD]
|
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|
| Stxbp2 |
- |
|
|
syntaxin binding protein; important for synaptic vesicle exoctyosis; may be a component of the SNARE complex; may be involved with …
|
View
|
| Anp32a |
- |
|
|
may play a role in differentiation of cerebellar neurons [RGD]
|
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|
| Pak3 |
- |
|
|
displays GTP-p21 mediated protein kinase activity [RGD]
|
View
|
| Pnlip |
- |
|
|
member of the lipase enzyme family which is involved in the hydrolysis of triglycerides to fatty acids [RGD]
|
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|
| Cplx2 |
- |
|
|
binds the assembled SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) complex; modulates synaptic vesicle exocytosis [RGD]
|
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|
| Slc28a2 |
- |
|
|
regulates adenosine transport across the blood-brain barrierinto the brain [RGD]
|
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|
| Cspg5 |
- |
|
|
proteoglycan expressed exclusively in brain and developing neurons [RGD]
|
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|
| Ace |
- |
|
|
catalyzes the conversion of angiotensin I to angiotensin II; plays a role in regulation of blood pressure [RGD]
|
View
|
| Ocm |
- |
|
|
calcium-binding protein; expression activated in a variety of tumors [RGD]
|
View
|
| Hnrpm |
- |
|
|
an RNA binding protein that interacts with carcinoembryonic antigen (CEA) [RGD]
|
View
|
| Olr1082 |
- |
|
|
member of the olfactory receptor family [RGD]
|
View
|
| Crybb3 |
- |
|
|
one of several lens beta crystallins [RGD]
|
View
|
| Cngb1 |
- |
|
|
may be involved in spermatogenesis [RGD]
|
View
|
| Dnajc5 |
- |
|
|
a component of the Hsp90 chaperone complex; involved in synaptic transmission [RGD]
|
View
|
| Gm1960 |
- |
|
|
acts as a chemoattractant for neutrophils; involved in the inflammatory response [RGD]
|
View
|
| Ton |
- |
|
|
serine protease involved in generating the octapeptide angiotensin II from precursors [RGD]
|
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|
| Tnp1 |
- |
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spermatid transitional protein; highly basic protein expressed during the brief period when histones are being replaced by protamines in the …
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| Eln |
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precursor of elastin, which is a major component of the elastic fibers of the extracellular matrix; confers elasticity to tissues …
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| Trh |
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mediates processes of vasopressin (AVP) and oxytocin (OT) biosynthesis and releases at the hypothalamo-neurohypophysial level [RGD]
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| Ugt2a1 |
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enzyme important for the elimination of potentially toxic compounds; found in the olfactory epithelium and may be involved with olfaction …
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| Vegp2 |
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may be a lipophilic-ligand carrier protein; may have a sensory function in the taste epithelium [RGD]
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| Vcsa1 |
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a prohormone-like protein [RGD]
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| Lta |
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cytokine produced by lymphocytes [RGD]
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| Fath2 |
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Drosophila and human homolog is a tumor suppressor gene [RGD]
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| TARDBPL |
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| Mep1a |
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alpha subunit of meprin metalloproteases, which form homotetramers and heterodimers with beta subunit Mep1b [RGD]
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| Mtap2 |
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regulates and organizes microtubules; may serve as a scaffolding protein for neuromodulatory activities [RGD]
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| Mog |
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a component of compact myelin of the CNS; may be involved in myelin stability [RGD]
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| Nat1 |
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enzyme that acetylates only aryl amines; may have a role in carcinogenesis [RGD]
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| Fxyd7 |
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involved in the control of ion transport; induces channel activity [RGD]
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| Olr1271 |
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member of the olfactory receptor family [RGD]
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| Gng7 |
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G-protein gamma subunit; may be component of G(olf) alpha-containing G protein that couples dopamine receptors selectively to ACST [RGD]
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| Hes2 |
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helix-loop-helix transcription factor; may act as a negative regulator of gene transcription [RGD]
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| Pamci |
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binds the cytoplasmic domain of peptidylglycine alpha-amidating monooxygenase (PAM), a peptide processing enzyme; may play a role in intracellular transport …
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| Hspb2 |
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a small heat shock protein [RGD]
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| Hpse |
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endo-beta-glucuronidase capable of cleaving heparan sulfate involved in the regulation of heparin sulfate proteoglycan function [RGD]
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| Hdgf |
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induces DNA replication in vascular smooth muscle cells [RGD]
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| Hdac3 |
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mouse homolog plays an important role in regulating cell cycle progression [RGD]
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| Fbp2 |
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last key-enzyme before the synthesis of glucose-6-phosphate of the gluconeogenic pathway [RGD]
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| Hadha |
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alpha subunit of the liver mitochondrial fatty acid oxidation multienzyme complex [RGD]
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| Bcat2 |
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mitochondrial branched-chain-amino-acid transaminase [RGD]
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| Cdh22 |
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mediates Ca2+ dependent cell adhesion; may play a role in brain and neuroendocrine organ morphogenesis [RGD]
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| Prnp |
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conformational conversion of gene product prion protein (PrP) associated with Prion diseases, fatal neurodegenerative disorders in man and animal [RGD]
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| Fxyd6 |
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involved in the control of ion transport or can induce channel activity [RGD]
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